GB971041A - New phenylpiperazine compounds - Google Patents
New phenylpiperazine compoundsInfo
- Publication number
- GB971041A GB971041A GB3728/60A GB372860A GB971041A GB 971041 A GB971041 A GB 971041A GB 3728/60 A GB3728/60 A GB 3728/60A GB 372860 A GB372860 A GB 372860A GB 971041 A GB971041 A GB 971041A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- nitro
- groups
- acylamido
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical class C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- XYVMOLOUBJBNBF-UHFFFAOYSA-N 3h-1,3-oxazol-2-one Chemical group OC1=NC=CO1 XYVMOLOUBJBNBF-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- -1 acylamido Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- FZERHIULMFGESH-UHFFFAOYSA-N N-phenylacetamide Chemical compound CC(=O)NC1=CC=CC=C1 FZERHIULMFGESH-UHFFFAOYSA-N 0.000 abstract 2
- 125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WNPSMKHXUKDOBN-UHFFFAOYSA-N 4-(2-bromoethyl)aniline Chemical compound NC1=CC=C(CCBr)C=C1 WNPSMKHXUKDOBN-UHFFFAOYSA-N 0.000 abstract 1
- CDIIZULDSLKBKV-UHFFFAOYSA-N 4-chlorobutanoyl chloride Chemical compound ClCCCC(Cl)=O CDIIZULDSLKBKV-UHFFFAOYSA-N 0.000 abstract 1
- 229960001413 acetanilide Drugs 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- QARBMVPHQWIHKH-UHFFFAOYSA-N methanesulfonyl chloride Chemical compound CS(Cl)(=O)=O QARBMVPHQWIHKH-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- PTEMXZYFVMYQKW-UHFFFAOYSA-N n-[4-(2-bromoethyl)phenyl]methanesulfonamide Chemical compound CS(=O)(=O)NC1=CC=C(CCBr)C=C1 PTEMXZYFVMYQKW-UHFFFAOYSA-N 0.000 abstract 1
- BVUUWWFHQIFUNM-UHFFFAOYSA-N n-[4-(4-chlorobutanoyl)phenyl]acetamide Chemical compound CC(=O)NC1=CC=C(C(=O)CCCCl)C=C1 BVUUWWFHQIFUNM-UHFFFAOYSA-N 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3728/60A GB971041A (en) | 1960-02-02 | 1960-02-02 | New phenylpiperazine compounds |
| LU39711D LU39711A1 (en:Method) | 1960-02-02 | 1961-01-30 | |
| ES0264470A ES264470A1 (es) | 1960-02-02 | 1961-01-31 | Procedimiento de preparaciën de compuestos de n-fenilpiperacina |
| BE599763A BE599763A (fr) | 1960-02-02 | 1961-02-01 | Nouveaux derives de la piperazine |
| FR851367A FR1421210A (fr) | 1960-02-02 | 1961-02-01 | Nouveaux dérivés de la pipérazine |
| CH122761A CH398614A (fr) | 1960-02-02 | 1961-02-02 | Procédé de préparation de nouveaux dérivés de la pipérazine |
| DEM47904A DE1201843B (de) | 1960-02-02 | 1961-02-02 | Verfahren zur Herstellung von N-Phenyl-piperazinderivaten |
| FR854365A FR1086M (fr) | 1960-02-02 | 1961-03-02 | Nouveaux dérivés de la n-phénylpipérazine. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3728/60A GB971041A (en) | 1960-02-02 | 1960-02-02 | New phenylpiperazine compounds |
| GB3121860 | 1960-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB971041A true GB971041A (en) | 1964-09-30 |
Family
ID=26238547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3728/60A Expired GB971041A (en) | 1960-02-02 | 1960-02-02 | New phenylpiperazine compounds |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE599763A (en:Method) |
| CH (1) | CH398614A (en:Method) |
| DE (1) | DE1201843B (en:Method) |
| ES (1) | ES264470A1 (en:Method) |
| FR (1) | FR1086M (en:Method) |
| GB (1) | GB971041A (en:Method) |
| LU (1) | LU39711A1 (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2515648A1 (fr) * | 1981-11-03 | 1983-05-06 | Cortial | Nouvelles (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique |
| FR2531082A1 (fr) * | 1982-07-29 | 1984-02-03 | Cortial | Nouvelles ((phenyl-4 piperazinylethyl)-2-anilino)-3 isobenzofurannones, leur methode de preparation et leur application therapeutique |
-
1960
- 1960-02-02 GB GB3728/60A patent/GB971041A/en not_active Expired
-
1961
- 1961-01-30 LU LU39711D patent/LU39711A1/xx unknown
- 1961-01-31 ES ES0264470A patent/ES264470A1/es not_active Expired
- 1961-02-01 BE BE599763A patent/BE599763A/fr unknown
- 1961-02-02 DE DEM47904A patent/DE1201843B/de active Pending
- 1961-02-02 CH CH122761A patent/CH398614A/fr unknown
- 1961-03-02 FR FR854365A patent/FR1086M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| LU39711A1 (en:Method) | 1961-03-30 |
| FR1086M (fr) | 1962-01-29 |
| BE599763A (fr) | 1961-05-29 |
| ES264470A1 (es) | 1961-04-16 |
| CH398614A (fr) | 1966-03-15 |
| DE1201843B (de) | 1965-09-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8207508A1 (es) | Un procedimiento para la preparacion dle derivados de un acido hidroxamico. | |
| GB1325192A (en) | Phloroglucinol derivatives | |
| GB925429A (en) | Indole derivatives | |
| ES444804A1 (es) | Procedimiento para la obtencion de derivados de tetrahidroi-soquinolina. | |
| GB1069797A (en) | ª-aminoketone derivatives | |
| GB971041A (en) | New phenylpiperazine compounds | |
| GB1028805A (en) | Novel hydroxy-amines | |
| US3905968A (en) | Preparation of 1,2-dichloro-3-amino propane derivatives | |
| GB1061946A (en) | Novel dibenzocycloheptene derivatives and a process for the manufacture thereof | |
| GB1460427A (en) | Phenothiazine derivatives | |
| GB858792A (en) | New pyridazine derivatives and processes for their manufacture | |
| ES8200689A1 (es) | Un procedimiento para la produccion de analogos de cefalosporina. | |
| US2759943A (en) | Derivatives of 2-n-methyl-1, 2, 3, 4-tetrahydro-gamma-carbolines | |
| US2828340A (en) | Hydroxy-lower-alkyl-bis(cyclohexylpropyl) amines, salts thereof, and preparation thereof | |
| US3167564A (en) | New process for the preparation of thiazole compounds | |
| GB959993A (en) | Camphor derivatives | |
| GB951026A (en) | The manufacture of sulphonamides | |
| US2762804A (en) | 3-methyl-5-phenyl-2, 6-piperazinedione and derivatives thereof and method of preparing same | |
| GB1205687A (en) | Aminoalkanol esters and their pharmaceutically acceptable acid-addition salts, and production thereof | |
| IE58684B1 (en) | Aminobenzamide derivatives | |
| GB1088224A (en) | Acetamidine derivatives | |
| GB1124663A (en) | New iminodibenzyls and a process for their preparation | |
| GB996702A (en) | Improvements in or relating to n-phenylpiperazine derivatives | |
| GB915964A (en) | New pyrazolidine derivatives and process for their manufacture | |
| GB887700A (en) | Improvements in and relating to benzo-1:3-thiazinediones-(2:4) |