GB949958A - Purified ferrimycin and process for obtaining same - Google Patents
Purified ferrimycin and process for obtaining sameInfo
- Publication number
- GB949958A GB949958A GB19076/60A GB1907660A GB949958A GB 949958 A GB949958 A GB 949958A GB 19076/60 A GB19076/60 A GB 19076/60A GB 1907660 A GB1907660 A GB 1907660A GB 949958 A GB949958 A GB 949958A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ferrimycin
- purified
- maxima
- dihydrochloride
- ultra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Crude ferrimycin, which may be obtained as described in Specification 893,880 or 912,339, may be purified by electrophoresis and/or countercurrent distribution with the use of benzyl alcohol, whereby the active substance is converted into two components ferrimycin A and ferrimycin B. Ferrimycin A may be further separated into components A1 and A2 by distribution chromatography, particularly on cellulose. Ferrimycin A dihydrochloride has the analytical composition C=48.65%, H=7.09%, N=12.95%, Fe=4.56%, Cl=6.10%, C(CH3)=1.99%, an equivalent weight of 1106 and maxima in the ultra-violet spectrum at 228 mm , 319 mm and 425 mm . Ferrimycin A1 dihydrochloride has the analytical composition C=47.63%, H=6.72%, Fe=4.88%, N=12.64%, Cl=6.40%, an equivalent weight of 1078 and maxima in the ultra-violet spectrum at 229 mm , 319 mm and 425 mm . Ferrimycin A2 dihydrochloride has the analytical composition C=48.78%, H=6.77%, Fe=5.29%, N=12.75%, Cl=6.23%, an equivalent weight of 984 and maxima in the ultra-violet spectrum at 227 mm , 319 mm and 425 mm .
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH7375559 | 1959-05-29 | ||
| CH306260A CH437638A (en) | 1960-03-18 | 1960-03-18 | Method of Purification of Ferrimycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB949958A true GB949958A (en) | 1964-02-19 |
Family
ID=25692071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19076/60A Expired GB949958A (en) | 1959-05-29 | 1960-05-30 | Purified ferrimycin and process for obtaining same |
Country Status (5)
| Country | Link |
|---|---|
| ES (1) | ES258439A1 (en) |
| FR (1) | FR352M (en) |
| GB (1) | GB949958A (en) |
| NL (1) | NL6811910A (en) |
| SE (1) | SE320762B (en) |
-
1960
- 1960-05-28 SE SE5286/60A patent/SE320762B/xx unknown
- 1960-05-28 ES ES0258439A patent/ES258439A1/en not_active Expired
- 1960-05-30 GB GB19076/60A patent/GB949958A/en not_active Expired
- 1960-08-29 FR FR836985A patent/FR352M/en active Active
-
1968
- 1968-08-21 NL NL6811910A patent/NL6811910A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6811910A (en) | 1968-10-25 |
| FR352M (en) | 1961-03-27 |
| ES258439A1 (en) | 1960-12-01 |
| SE320762B (en) | 1970-02-16 |
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