GB935672A - Sustained release tablet - Google Patents

Sustained release tablet

Info

Publication number
GB935672A
GB935672A GB25563/61A GB2556361A GB935672A GB 935672 A GB935672 A GB 935672A GB 25563/61 A GB25563/61 A GB 25563/61A GB 2556361 A GB2556361 A GB 2556361A GB 935672 A GB935672 A GB 935672A
Authority
GB
United Kingdom
Prior art keywords
hydrochloride
optionally
medicaments
sustained release
release tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25563/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of GB935672A publication Critical patent/GB935672A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical sustained release tablet is composed of a solid medicament uniformly distributed in a matrix composed essentially of zein (preferably 45-75% by weight) and a solid hexitan tri-ester of a higher aliphatic acid, e.g. sorbitan tristearate (preferably 25-55%). Optionally there may also be present about 1-3% of a tableting lubricant and up to 33% (of the matrix) of an inert diluent. Specified medicaments are antispasmodics, e.g. penthienate bromide, atropine and hyoscyamine; barbiturates, e.g. phenobarbital, mephobarbital and talbutal; tranquilizers, e.g. meprobamate; antihistamines, e.g. dethylandiamine hydrochloride and thonzylamine hydrochloride; antibiotics, e.g. tetracycline and procaine penicillin; vasodilators, e.g. pentaerythritol tetranitrate; vasopressors, e.g. levarterenol bitartrate, phenylephrine hydrochloride and isoproterenol hydrochloride; muscle relaxants, e.g. chlormethazanone; analgesics, e.g. meperidine hydrochloride, acetyl salicylic acid and salicylamide; vitamins, hormones and anti-infective, sedative and hypnotic agents. The tablets may optionally be coated and the coatings may contain the same or other medicaments to the core.
GB25563/61A 1960-07-19 1961-07-14 Sustained release tablet Expired GB935672A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4374060A 1960-07-19 1960-07-19

Publications (1)

Publication Number Publication Date
GB935672A true GB935672A (en) 1963-09-04

Family

ID=21928651

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25563/61A Expired GB935672A (en) 1960-07-19 1961-07-14 Sustained release tablet

Country Status (3)

Country Link
BE (1) BE606331A (en)
FR (1) FR1314M (en)
GB (1) GB935672A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158277A2 (en) * 1984-04-11 1985-10-16 Hoechst Aktiengesellschaft Implantable controlled-release preparations of regulatory peptides, and process for their preparation
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
WO2002043706A2 (en) * 2000-12-01 2002-06-06 Labopharm Inc. Prolamin-based sustained-release compositions and delayed-onset compositions
CN101669899B (en) * 2009-09-29 2011-02-02 河北科技大学 Sustained-release implant taking maize protein as main framework material or matrix and use thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4137300A (en) * 1976-08-20 1979-01-30 Ciba-Geigy Corporation Sustained action dosage forms

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158277A2 (en) * 1984-04-11 1985-10-16 Hoechst Aktiengesellschaft Implantable controlled-release preparations of regulatory peptides, and process for their preparation
EP0158277A3 (en) * 1984-04-11 1987-04-29 Hoechst Aktiengesellschaft Implantable controlled-release preparations of regulatory peptides, and process for their preparation
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
WO1993012772A1 (en) * 1991-12-31 1993-07-08 Abbott Laboratories System for delivering an active substance for sustained release
WO2002043706A2 (en) * 2000-12-01 2002-06-06 Labopharm Inc. Prolamin-based sustained-release compositions and delayed-onset compositions
WO2002043706A3 (en) * 2000-12-01 2003-03-27 Labopharm Inc Prolamin-based sustained-release compositions and delayed-onset compositions
CN101669899B (en) * 2009-09-29 2011-02-02 河北科技大学 Sustained-release implant taking maize protein as main framework material or matrix and use thereof

Also Published As

Publication number Publication date
BE606331A (en) 1962-01-19
FR1314M (en) 1962-05-14

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