GB933826A - Production of 5'-nucleotides and of nucleosides - Google Patents

Production of 5'-nucleotides and of nucleosides

Info

Publication number
GB933826A
GB933826A GB23287/60A GB2328760A GB933826A GB 933826 A GB933826 A GB 933826A GB 23287/60 A GB23287/60 A GB 23287/60A GB 2328760 A GB2328760 A GB 2328760A GB 933826 A GB933826 A GB 933826A
Authority
GB
United Kingdom
Prior art keywords
phosphomonoesterase
nucleotides
living cells
enzyme system
produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23287/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of GB933826A publication Critical patent/GB933826A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/23—Synthetic spices, flavouring agents or condiments containing nucleotides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

51-Nucleotides and/or nucleosides are produced by bringing a ribonucleic acid and/or oligoribonucleotide and/or a 21-desoxy compound thereof into contact at a pH between 4 and 10 with living cells of, or an enzyme system produced by, a microorganism belonging to the order Sphaeriales, said enzyme system containing or living cells producing phosphodiesterase, with or without phosphomonoesterase and/or adenylic deaminase. Suitable microorganisms include those of genera Anixiella, Botryosphaeria, Chaetomidium, Glomerella, Neurospora, Ophiobolus, Ophiostoma, Sordaria and Tilachlidium. Phosphomonoesterase inhibitors may be present as may accelerators such as magnesium salts. Phosphomonoesterase may also be inactivated by heating for about 5 minutes at about 60 DEG C. and pH 4-7. The nucleotides may be isolated as salts, e.g. with Ba, Ca, K, NH4, amino acids, cyclohexylamine or brucine. The nucleotides may be used in seasonings (Group VI).ALSO:A seasoning comprises, together with an inert carrier, a 51-nucleotide which has been produced by bringing a ribonucleic acid and/or oligoribonucleotide and/or a 21-desoxy compound thereof into contact, at a pH between 4 and 10, with living cells of, or an enzyme system produced by, a micro-organism belonging to the order Sphaeriales, e.g. genera Anixiella, Botryosphaeria, Chaetomidium, Glomerella, Neurospora, Ophiobolus, Ophiostoma, Sordaria or Tilachlidium, said enzyme system containing, or the living cells producing, phosphodiesterase, with or without phosphomonoesterase and/or adenylic deaminase.
GB23287/60A 1959-07-04 1960-07-04 Production of 5'-nucleotides and of nucleosides Expired GB933826A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2188459 1959-07-04

Publications (1)

Publication Number Publication Date
GB933826A true GB933826A (en) 1963-08-14

Family

ID=12067529

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23287/60A Expired GB933826A (en) 1959-07-04 1960-07-04 Production of 5'-nucleotides and of nucleosides

Country Status (3)

Country Link
CH (1) CH479593A (en)
DE (1) DE1445158A1 (en)
GB (1) GB933826A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068002A1 (en) * 2002-02-12 2003-08-21 Norferm Da Bacterial hydrolysate
US7700140B2 (en) 2002-02-12 2010-04-20 Statoil Asa Bacterial autolysate

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068002A1 (en) * 2002-02-12 2003-08-21 Norferm Da Bacterial hydrolysate
US7687091B2 (en) 2002-02-12 2010-03-30 Statoil Asa Bacterial hydrolystate
US7700140B2 (en) 2002-02-12 2010-04-20 Statoil Asa Bacterial autolysate

Also Published As

Publication number Publication date
CH479593A (en) 1969-10-15
DE1445158A1 (en) 1969-10-09

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