GB9305466D0 - Substitued cephalosporin sulfones useful in the treatment of cancer - Google Patents

Substitued cephalosporin sulfones useful in the treatment of cancer

Info

Publication number
GB9305466D0
GB9305466D0 GB939305466A GB9305466A GB9305466D0 GB 9305466 D0 GB9305466 D0 GB 9305466D0 GB 939305466 A GB939305466 A GB 939305466A GB 9305466 A GB9305466 A GB 9305466A GB 9305466 D0 GB9305466 D0 GB 9305466D0
Authority
GB
United Kingdom
Prior art keywords
substitued
cancer
treatment
cephalosporin sulfones
sulfones useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB939305466A
Other versions
GB2266525A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB9305466D0 publication Critical patent/GB9305466D0/en
Publication of GB2266525A publication Critical patent/GB2266525A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9305466A 1992-03-17 1993-03-17 Substituted cephalosporin sulfone compositions useful in the treatment of leukemia Withdrawn GB2266525A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85259092A 1992-03-17 1992-03-17

Publications (2)

Publication Number Publication Date
GB9305466D0 true GB9305466D0 (en) 1993-05-05
GB2266525A GB2266525A (en) 1993-11-03

Family

ID=25313731

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9305466A Withdrawn GB2266525A (en) 1992-03-17 1993-03-17 Substituted cephalosporin sulfone compositions useful in the treatment of leukemia

Country Status (1)

Country Link
GB (1) GB2266525A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314562D0 (en) * 1993-07-14 1993-08-25 Erba Carlo Spa Use of cephem derivatives as anti-metastatic agents
WO1997008174A1 (en) * 1995-08-31 1997-03-06 Smithkline Beecham Corporation Interleukin converting enzyme and apoptosis
JPH11514345A (en) * 1995-08-31 1999-12-07 スミスクライン・ビーチャム・コーポレイション Interleukin converting enzyme and apoptosis
EP0834556A1 (en) * 1996-09-25 1998-04-08 Academisch Ziekenhuis Leiden Methods for culturing cells
US7151092B2 (en) 2002-10-31 2006-12-19 Metabasis Therapeutics, Inc. Cytarabine monophosphate prodrugs
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
EP3164136A4 (en) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
AU2019207625A1 (en) 2018-01-09 2020-07-30 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267723B1 (en) * 1986-11-12 1996-02-07 Merck & Co. Inc. New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents

Also Published As

Publication number Publication date
GB2266525A (en) 1993-11-03

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)