GB9300960D0 - Multivalent anti-cytokine immunoglobulins - Google Patents

Multivalent anti-cytokine immunoglobulins

Info

Publication number
GB9300960D0
GB9300960D0 GB939300960A GB9300960A GB9300960D0 GB 9300960 D0 GB9300960 D0 GB 9300960D0 GB 939300960 A GB939300960 A GB 939300960A GB 9300960 A GB9300960 A GB 9300960A GB 9300960 D0 GB9300960 D0 GB 9300960D0
Authority
GB
United Kingdom
Prior art keywords
multivalent anti
immunoglobulins
cytokine
cytokine immunoglobulins
multivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB939300960A
Other versions
GB2261666A (en
GB2261666B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of GB9300960D0 publication Critical patent/GB9300960D0/en
Publication of GB2261666A publication Critical patent/GB2261666A/en
Application granted granted Critical
Publication of GB2261666B publication Critical patent/GB2261666B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
GB9300960A 1990-07-19 1993-01-19 Multivalent anti-cytokine immunoglobulins Expired - Fee Related GB2261666B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909015908A GB9015908D0 (en) 1990-07-19 1990-07-19 Multivalent immunoglobulin
PCT/GB1991/001216 WO1992001472A1 (en) 1990-07-19 1991-07-19 Multivalent anti-cytokine immunoglobulins

Publications (3)

Publication Number Publication Date
GB9300960D0 true GB9300960D0 (en) 1993-03-17
GB2261666A GB2261666A (en) 1993-05-26
GB2261666B GB2261666B (en) 1994-07-27

Family

ID=10679355

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909015908A Pending GB9015908D0 (en) 1990-07-19 1990-07-19 Multivalent immunoglobulin
GB9300960A Expired - Fee Related GB2261666B (en) 1990-07-19 1993-01-19 Multivalent anti-cytokine immunoglobulins

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909015908A Pending GB9015908D0 (en) 1990-07-19 1990-07-19 Multivalent immunoglobulin

Country Status (7)

Country Link
EP (1) EP0539455A1 (en)
JP (1) JPH06501840A (en)
KR (1) KR930701192A (en)
AU (1) AU8238191A (en)
CA (1) CA2087541A1 (en)
GB (2) GB9015908D0 (en)
WO (1) WO1992001472A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192584B2 (en) 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
US6277969B1 (en) 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US6284471B1 (en) 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
US6180377B1 (en) * 1993-06-16 2001-01-30 Celltech Therapeutics Limited Humanized antibodies
US5478753A (en) * 1993-06-29 1995-12-26 Pb Diagnostic Systems, Inc. Positive calibrator/control composition for an IgM serology assay and an IgM serology assay
FR2707882B1 (en) * 1993-07-23 1997-08-01 Immunotech Sa New protein anti-mediator therapeutic kits, preparation process and pharmaceutical compositions containing them.
GB2281300A (en) * 1993-08-26 1995-03-01 Merck & Co Inc Anti-HIV antibody oligomer
PL318501A1 (en) * 1994-07-22 1997-06-23 Hoffmann La Roche Pharmaceutic compositions containing a tnc bonding chimeric protein
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
DE69724451T2 (en) 1996-12-06 2004-03-18 Amgen Inc., Thousand Oaks COMBINATION THERAPY WITH A TNF-BINDING PROTEIN FOR TREATING DISEASES CAUSED BY TNF
US20040220103A1 (en) 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
AU3082401A (en) * 1999-11-24 2001-06-04 Centocor Inc. Therapy of psoriasis
TWI327597B (en) 2001-08-01 2010-07-21 Centocor Inc Anti-tnf antibodies, compositions, methods and uses
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
JP7179464B2 (en) 2015-01-20 2022-11-29 アイジーエム バイオサイエンシズ インコーポレイテッド Tumor necrosis factor (TNF) superfamily receptor-binding molecules and their uses
WO2017040195A1 (en) * 2015-08-28 2017-03-09 The Trustees Of The University Of Pennsylvania Methods and compositions for cells expressing a chimeric intracellular signaling molecule
CN108135932A (en) 2015-08-28 2018-06-08 宾夕法尼亚大学董事会 Express the method and composition of the cell of signal transduction molecule in chimeric cell
US10465003B2 (en) 2016-02-05 2019-11-05 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3834589A (en) * 1988-05-31 1990-01-05 Schering Biotech Corporation Method of treating myeloid leukemias
AU4035189A (en) * 1988-08-19 1990-03-23 Upjohn Company, The Renin inhibitory peptides containing suleptanic acid or derivatives thereof
EP0355067A1 (en) * 1988-08-19 1990-02-21 Celltech Limited Pharmaceutical products for anti-neoplastic therapy
FR2640146B1 (en) * 1988-12-08 1993-12-24 Commissariat A Energie Atomique ANTI-INTERLEUKIN MONOCLONAL ANTIBODIES 1 (ALPHA) AND 1 (BETA), THEIR PRODUCTION METHOD AND APPLICATIONS OF SAID ANTIBODIES TO DETECTION OF INTERLEUKINS 1 (ALPHA) AND 1 (BETA) AND THERAPEUTICS
FR2640143B1 (en) * 1988-12-13 1991-03-15 Maes Ludo POLYMERIZED ANTIBODIES, DIRECTED AGAINST IMMUNOGLOBULINS - THEIR USE IN DIAGNOSTIC TESTS
EP0462246A4 (en) * 1989-11-07 1992-11-25 Bristol-Myers Squibb Company Oligomeric immunoglobulins

Also Published As

Publication number Publication date
EP0539455A1 (en) 1993-05-05
CA2087541A1 (en) 1992-01-20
GB9015908D0 (en) 1990-09-05
WO1992001472A1 (en) 1992-02-06
GB2261666A (en) 1993-05-26
KR930701192A (en) 1993-06-11
AU8238191A (en) 1992-02-18
JPH06501840A (en) 1994-03-03
GB2261666B (en) 1994-07-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950719