GB916455A - Non-toxic antigens and process for producing same - Google Patents

Non-toxic antigens and process for producing same

Info

Publication number
GB916455A
GB916455A GB25289/61A GB2528961A GB916455A GB 916455 A GB916455 A GB 916455A GB 25289/61 A GB25289/61 A GB 25289/61A GB 2528961 A GB2528961 A GB 2528961A GB 916455 A GB916455 A GB 916455A
Authority
GB
United Kingdom
Prior art keywords
toxic
protein
antigen
producing same
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25289/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of GB916455A publication Critical patent/GB916455A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A synthetic non-toxic antigen, which when used to inoculate a living organism is effective in producing antibodies against Gram-negative bacteria, has as a constituent of a determinant group thereof at least one 3,6-didesoxyhexose coupled to a protein which is physiologically acceptable by the organism to be inoculated. The 3,6-didesoxy-hexose may be abequose, colitose, tyvelose, paratose or ascarylose, and the protein may be serum albumin or serum globulin. The synthetic antigen may be applied together with a non-toxic pharmaceutical carrier such as a sterile isotonic aqueous solution containing a preservative. Specification 725,938 is referred to.
GB25289/61A 1960-07-12 1961-07-12 Non-toxic antigens and process for producing same Expired GB916455A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH793560A CH396316A (en) 1960-07-12 1960-07-12 Process for the manufacture of vaccines

Publications (1)

Publication Number Publication Date
GB916455A true GB916455A (en) 1963-01-23

Family

ID=4332624

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25289/61A Expired GB916455A (en) 1960-07-12 1961-07-12 Non-toxic antigens and process for producing same

Country Status (4)

Country Link
CH (1) CH396316A (en)
ES (1) ES268958A1 (en)
FR (1) FR1175M (en)
GB (1) GB916455A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123114A1 (en) * 1983-03-28 1984-10-31 Miles Laboratories, Inc. Urea-linked immunogens, antibodies, and preparative method
EP0097407B1 (en) * 1982-06-22 1987-05-13 Rijksuniversiteit Utrecht Vaccines against diseases causing bacteria with capsular polysaccharides and process of preparing them
EP0306607A1 (en) * 1983-03-14 1989-03-15 Miles Inc. Vaccines for gram-negative bacteria

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097407B1 (en) * 1982-06-22 1987-05-13 Rijksuniversiteit Utrecht Vaccines against diseases causing bacteria with capsular polysaccharides and process of preparing them
EP0306607A1 (en) * 1983-03-14 1989-03-15 Miles Inc. Vaccines for gram-negative bacteria
EP0123114A1 (en) * 1983-03-28 1984-10-31 Miles Laboratories, Inc. Urea-linked immunogens, antibodies, and preparative method

Also Published As

Publication number Publication date
FR1175M (en) 1962-03-12
CH396316A (en) 1965-07-31
ES268958A1 (en) 1961-12-16

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