GB900640A - A process for the production of an antibiotic - Google Patents
A process for the production of an antibioticInfo
- Publication number
- GB900640A GB900640A GB23642/58A GB2364258A GB900640A GB 900640 A GB900640 A GB 900640A GB 23642/58 A GB23642/58 A GB 23642/58A GB 2364258 A GB2364258 A GB 2364258A GB 900640 A GB900640 A GB 900640A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propionibacterium
- antibiotic
- cytostatic
- carbohydrates
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Abstract
An antibiotic, which is cytostatic, is produced by the anaerobic fermentation of bacteria which are capable of forming propionic acid by the degradation of carbohydrates in a nutrient medium containing carbohydrates and having a pH of 6.8 to 7.2, the cultivation being continued for 3 to 5 days at a temperature of 20-40 DEG C. and thereafter isolating the antibiotic from the fermentation broth. The broth is preferably clarified and extracted with an organic solvent such as ethyl ether, the antibiotic being recovered by evaporating the solvent in vacuo. Specified bacteria are Propionibacterium freudenreichii, Propionibacterium rubrum, Propionibacterium technicum and Clostridium propionicum. The antibiotic may be used medicinally as a cytostatic or for the treatment of rumenatony in ruminants (see Group VI).ALSO:An oral or rectal preparation or injection comprises as an essential ingredient thereof the cytostatic substance isolated from a culture broth in which has been anaerobically fermented bacteria capable of forming propionic acid by the degradation of carbohydrates especially Propionibacterium freudenreichii, Propionibacterium rubrum, Propionibacterium technicum and Clastridium propionicum. The culture medium may be used for the treatment of rumenatony in ruminants. Sterile aqueous or aqueous alcoholic suspensions may be used for injection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB23642/58A GB900640A (en) | 1958-07-23 | 1958-07-23 | A process for the production of an antibiotic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB23642/58A GB900640A (en) | 1958-07-23 | 1958-07-23 | A process for the production of an antibiotic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB900640A true GB900640A (en) | 1962-07-11 |
Family
ID=10198940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB23642/58A Expired GB900640A (en) | 1958-07-23 | 1958-07-23 | A process for the production of an antibiotic |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB900640A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106831127A (en) * | 2017-01-25 | 2017-06-13 | 云南顺丰洱海环保科技股份有限公司 | A kind of organic fertilizer |
-
1958
- 1958-07-23 GB GB23642/58A patent/GB900640A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106831127A (en) * | 2017-01-25 | 2017-06-13 | 云南顺丰洱海环保科技股份有限公司 | A kind of organic fertilizer |
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