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Expired
Application number
GB39031/60A
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Laboratoires Francais de Chimiotherapie SA
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Laboratoires Francais de Chimiotherapie SA
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Publication of GB890774ApublicationCriticalpatent/GB890774A/en
C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
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Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Health & Medical Sciences
(AREA)
General Health & Medical Sciences
(AREA)
Steroid Compounds
(AREA)
Abstract
The invention comprises 2-bromo-testosterone and a process for the preparation thereof by reacting 2-methoxyoxalyl- or 2-ethoxyoxalyl-testosterone having the formula <FORM:0890774/IV (b)/1> in which R represents either a methyl or an ethyl group, with bromine in an alkaline medium. Subsequently HBr may be eliminated from the product to obtain D 1-testosterone, e.g. using a lithium bromide, lithium carbonate couple.
GB39031/60A1959-11-241960-11-14A new steroid derivative, its preparation and conversion into therapeutically useful compounds
ExpiredGB890774A
(en)
A new octadecapeptide of the formula l-asparaginyl-l-seryl-glycol-l-propyl-l-tyrosyl-l-lysyl-l-methionyl-l-glutaminyl-l-histidyl-l-phenyl-alanyl-l-arginyl-l-tryptophyl-glycyl-l-seryl-l-prolyl-l-prolyl-l-lysyl-l-asparaginio acid