GB886035A - ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine - Google Patents

ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine

Info

Publication number
GB886035A
GB886035A GB1393559A GB1393559A GB886035A GB 886035 A GB886035 A GB 886035A GB 1393559 A GB1393559 A GB 1393559A GB 1393559 A GB1393559 A GB 1393559A GB 886035 A GB886035 A GB 886035A
Authority
GB
United Kingdom
Prior art keywords
phenyl
methyl
propiophenone
hydroxyethylamino
diethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1393559A
Inventor
Raffaello Fusco
Giuseppe Bianchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Industria Chimica Profarmaco SpA
Original Assignee
Industria Chimica Profarmaco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Industria Chimica Profarmaco SpA filed Critical Industria Chimica Profarmaco SpA
Priority to GB1393559A priority Critical patent/GB886035A/en
Publication of GB886035A publication Critical patent/GB886035A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Abstract

The invention comprises a -(b -hydroxyethylamino)-propiophenone and the preparation thereof by reacting a -bromo-propiophenone and monoethanolamine, and the preparation of b -phenyl-a -methyl-diethanolamine by reducing a - (b - hydroxyethylamino) - propiophenone with sodium borohydride with the optional further step of cyclizing the diethanolamine to form 2-phenyl-3-methyl-morpholine, e.g. with sulphuric acid. Detailed examples are given.
GB1393559A 1959-04-23 1959-04-23 ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine Expired GB886035A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1393559A GB886035A (en) 1959-04-23 1959-04-23 ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1393559A GB886035A (en) 1959-04-23 1959-04-23 ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine

Publications (1)

Publication Number Publication Date
GB886035A true GB886035A (en) 1962-01-03

Family

ID=10032048

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1393559A Expired GB886035A (en) 1959-04-23 1959-04-23 ª--(ª--hydroxyethylamino)-propiophenone, its production and its conversion into ª--phenyl-ª--methyl-diethanolamine and 2-phenyl-3-methyl-morpholine

Country Status (1)

Country Link
GB (1) GB886035A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2626879A1 (en) * 1988-02-10 1989-08-11 Lafon Labor 1-(Aminophenyl)-2-(N-2-hydroxyethylamino)propanone derivatives, process of preparation and use in therapeutics
JP2013049680A (en) * 2006-03-09 2013-03-14 Biocopea Ltd Use of beta-aminoalcohol in treatment of inflammatory disease and pain

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2626879A1 (en) * 1988-02-10 1989-08-11 Lafon Labor 1-(Aminophenyl)-2-(N-2-hydroxyethylamino)propanone derivatives, process of preparation and use in therapeutics
JP2013049680A (en) * 2006-03-09 2013-03-14 Biocopea Ltd Use of beta-aminoalcohol in treatment of inflammatory disease and pain

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