GB8829088D0 - Compounds - Google Patents

Compounds

Info

Publication number
GB8829088D0
GB8829088D0 GB888829088A GB8829088A GB8829088D0 GB 8829088 D0 GB8829088 D0 GB 8829088D0 GB 888829088 A GB888829088 A GB 888829088A GB 8829088 A GB8829088 A GB 8829088A GB 8829088 D0 GB8829088 D0 GB 8829088D0
Authority
GB
United Kingdom
Prior art keywords
compounds
unit
2alkyl
4alkyl
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB888829088A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Priority to GB888829088A priority Critical patent/GB8829088D0/en
Publication of GB8829088D0 publication Critical patent/GB8829088D0/en
Priority to CA002004706A priority patent/CA2004706A1/en
Priority to IL92566A priority patent/IL92566A0/en
Priority to PT92531A priority patent/PT92531B/en
Priority to MYPI89001724A priority patent/MY105079A/en
Priority to DK621289A priority patent/DK621289A/en
Priority to AT89312898T priority patent/ATE113299T1/en
Priority to DE68919061T priority patent/DE68919061T2/en
Priority to ES89312898T priority patent/ES2063829T3/en
Priority to EP89312898A priority patent/EP0373852B1/en
Priority to CN89109760A priority patent/CN1044105A/en
Priority to ZW165/89A priority patent/ZW16589A1/en
Priority to AU46080/89A priority patent/AU620183B2/en
Priority to KR1019890018425A priority patent/KR900009725A/en
Priority to NO89894995A priority patent/NO894995L/en
Priority to ZA899467A priority patent/ZA899467B/en
Priority to FI895936A priority patent/FI895936A7/en
Priority to HU896510A priority patent/HU209397B/en
Priority to NZ231728A priority patent/NZ231728A/en
Priority to IE893966A priority patent/IE893966L/en
Priority to JP1323653A priority patent/JPH02212505A/en
Priority to US07/837,793 priority patent/US5441731A/en
Priority to MX9203549A priority patent/MX9203549A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C08F265/06—Polymerisation of acrylate or methacrylate esters on to polymers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C07C69/653—Acrylic acid esters; Methacrylic acid esters; Haloacrylic acid esters; Halomethacrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

Polymers of structure: <CHEM> in which X is a cross-linking unit, X<1> is a comonomer unit, R<1> is hydrogen or C1-4alkyl and R<1> and R<2> are the same or different and are each C1-2alkyl or aralkyl, or R<1> to R<3> together form a ring, compositions containing them and their use in therapy for the lowering of serum cholesterol levels.
GB888829088A 1988-12-13 1988-12-13 Compounds Pending GB8829088D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GB888829088A GB8829088D0 (en) 1988-12-13 1988-12-13 Compounds
CA002004706A CA2004706A1 (en) 1988-12-13 1989-12-06 Compounds
IL92566A IL92566A0 (en) 1988-12-13 1989-12-06 Anion exchange methacrylate copolymers,processes for their preparation and pharmaceutical compositions containing them
PT92531A PT92531B (en) 1988-12-13 1989-12-07 PROCESS OF PREPARATION OF REPLACED METACRYLATE POLYMERES
MYPI89001724A MY105079A (en) 1988-12-13 1989-12-07 Compounds.
DK621289A DK621289A (en) 1988-12-13 1989-12-08 POLYMER COMPOUNDS, PROCEDURES FOR THE MANUFACTURING THEREOF AND THEIR USE
AU46080/89A AU620183B2 (en) 1988-12-13 1989-12-11 Aminated acrylate polymers
CN89109760A CN1044105A (en) 1988-12-13 1989-12-11 Compound
DE68919061T DE68919061T2 (en) 1988-12-13 1989-12-11 Links.
ES89312898T ES2063829T3 (en) 1988-12-13 1989-12-11 COMPOUNDS.
EP89312898A EP0373852B1 (en) 1988-12-13 1989-12-11 Compounds
AT89312898T ATE113299T1 (en) 1988-12-13 1989-12-11 LINKS.
ZW165/89A ZW16589A1 (en) 1988-12-13 1989-12-11 Anion exchange polymer compounds
IE893966A IE893966L (en) 1988-12-13 1989-12-12 Compounds
ZA899467A ZA899467B (en) 1988-12-13 1989-12-12 Compounds
NO89894995A NO894995L (en) 1988-12-13 1989-12-12 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ANION EXCHANGE POLYMERS.
KR1019890018425A KR900009725A (en) 1988-12-13 1989-12-12 compound
FI895936A FI895936A7 (en) 1988-12-13 1989-12-12 Compounds
HU896510A HU209397B (en) 1988-12-13 1989-12-12 Process for production of anion-changing polimers and medical compositions containing such polimers
NZ231728A NZ231728A (en) 1988-12-13 1989-12-12 Quaternised aminoalkylacrylate polymers, preparation and pharmaceutical compositions thereof
JP1323653A JPH02212505A (en) 1988-12-13 1989-12-13 Anion exchange polymer
US07/837,793 US5441731A (en) 1988-12-13 1992-02-18 Compounds
MX9203549A MX9203549A (en) 1988-12-13 1992-06-26 COMPOUNDS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829088A GB8829088D0 (en) 1988-12-13 1988-12-13 Compounds

Publications (1)

Publication Number Publication Date
GB8829088D0 true GB8829088D0 (en) 1989-01-25

Family

ID=10648421

Family Applications (1)

Application Number Title Priority Date Filing Date
GB888829088A Pending GB8829088D0 (en) 1988-12-13 1988-12-13 Compounds

Country Status (21)

Country Link
US (1) US5441731A (en)
EP (1) EP0373852B1 (en)
JP (1) JPH02212505A (en)
KR (1) KR900009725A (en)
CN (1) CN1044105A (en)
AT (1) ATE113299T1 (en)
AU (1) AU620183B2 (en)
CA (1) CA2004706A1 (en)
DE (1) DE68919061T2 (en)
DK (1) DK621289A (en)
ES (1) ES2063829T3 (en)
FI (1) FI895936A7 (en)
GB (1) GB8829088D0 (en)
HU (1) HU209397B (en)
IE (1) IE893966L (en)
MY (1) MY105079A (en)
NO (1) NO894995L (en)
NZ (1) NZ231728A (en)
PT (1) PT92531B (en)
ZA (1) ZA899467B (en)
ZW (1) ZW16589A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0622078B1 (en) * 1992-01-14 1999-09-01 Hisamitsu Pharmaceutical Co., Inc. Cholesterol level depressant
US5556619A (en) * 1992-08-20 1996-09-17 The Du Pont Merck Pharmaceutical Company Crosslinked polymeric ammonium salts
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
JPH09500368A (en) * 1993-06-02 1997-01-14 ジェルテックス ファーマシューティカルズ，インコーポレイテッド Compositions and methods for removing bile salts
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
ZA95390B (en) * 1994-01-18 1996-07-18 Du Pont Crosslinked polymeric ammonium salts
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
IL139728A (en) * 1995-01-09 2003-06-24 Penwest Pharmaceuticals Compan Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5936003A (en) * 1997-03-03 1999-08-10 Dionex Corporation Hydrolytically stable resins for use in anion-exchange chromatography
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
KR100381512B1 (en) * 2000-09-21 2003-04-26 굿젠 주식회사 Cationic lipids and use thereof
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
EP2269589B1 (en) 2004-03-30 2013-12-25 Relypsa, Inc. Ion binding polymers and uses thereof
JP5000480B2 (en) 2004-03-30 2012-08-15 レリプサ， インコーポレイテッド Methods and compositions for treatment of ion balance abnormalities
DE112006002617T5 (en) 2005-09-30 2008-08-28 Ilypsa Inc., Santa Clara Process for the preparation of core-shell composites or core-shell composites with crosslinked shells and resulting core-shell composites
BRPI0616604A2 (en) 2005-09-30 2012-12-25 Ilypsa Inc Method for Removing and Composition for Selectively Removing Potassium Ion from a Mammal's Gastrointestinal Tract, Method for Selectively Removing Potassium Ion from an Environment, Pharmaceutical Composition, Core-Wrap Particle, and, Uses of a Core-Wrap Particle and a pharmaceutical composition
EP2957286B1 (en) † 2008-08-22 2018-11-21 Vifor (International) Ltd. Compositions comprising crosslinked cation exchange polymers and use in treating hyperkalemia

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843573A (en) * 1955-03-21 1958-07-15 Rohm & Haas New quaternary ammonium compounds in which the nitrogen atom carries an alkoxymethyl group
DE1065181B (en) * 1956-11-28 1959-09-10 Rohm S. Haas Company, Philadelphia, Pa. (V. St. A.) Process for the production of a weakly basic anion-adsorbing as well as strongly basic, quaternary ammonium group-containing anion exchange resin
DE1233604B (en) * 1961-09-08 1967-02-02 Du Pont Process for the production of copolymers containing amine oxide groups
BE756035A (en) * 1969-09-12 1971-03-11 Inveresk Res Int POLYMERS BRIDGES
GB1309496A (en) * 1970-05-20 1973-03-14 Mitsubishi Gas Chemical Co Process for producing cationic synthetic latex
CS171962B1 (en) * 1974-02-01 1976-11-29
JPS50110482A (en) * 1974-02-13 1975-08-30
JPS52127995A (en) * 1976-04-19 1977-10-27 Johnson & Johnson Hydrophilic random copolymers composition and process for producing same
US4393145A (en) * 1979-05-01 1983-07-12 Etablissement Texcontor Anionic ion exchange resins with cholesterol-decreasing properties
JPS58154709A (en) * 1982-03-09 1983-09-14 Kyoritsu Yuki Kogyo Kenkyusho:Kk Production of cationic, highly water-absorptive resin
DE3587419T2 (en) * 1985-01-07 1993-12-16 Rhone Poulenc Spec Chim Polymers containing carboxyl groups, process for their preparation and their use.
US4621120A (en) * 1985-04-01 1986-11-04 Eastman Kodak Company Polymeric antibacterial compositions
JPH075683B2 (en) * 1986-09-09 1995-01-25 三菱レイヨン株式会社 Method for producing methacrylic resin cast plate excellent in antistatic property
US4981936A (en) * 1989-04-14 1991-01-01 Polypure, Inc. Terpolymer of oxyalkyene acrylates, acrylamides and quaternary monomers

Also Published As

Publication number Publication date
HU896510D0 (en) 1990-02-28
CN1044105A (en) 1990-07-25
US5441731A (en) 1995-08-15
ES2063829T3 (en) 1995-01-16
PT92531B (en) 1995-08-09
MY105079A (en) 1994-07-30
PT92531A (en) 1990-06-29
DE68919061T2 (en) 1995-04-06
ZA899467B (en) 1991-07-31
ATE113299T1 (en) 1994-11-15
EP0373852A2 (en) 1990-06-20
IE893966L (en) 1990-06-13
HUT53135A (en) 1990-09-28
EP0373852B1 (en) 1994-10-26
NO894995L (en) 1990-06-14
DK621289D0 (en) 1989-12-08
FI895936A0 (en) 1989-12-12
AU4608089A (en) 1990-06-21
DE68919061D1 (en) 1994-12-01
ZW16589A1 (en) 1990-10-10
KR900009725A (en) 1990-07-05
HU209397B (en) 1994-05-30
EP0373852A3 (en) 1991-12-27
JPH02212505A (en) 1990-08-23
AU620183B2 (en) 1992-02-13
NZ231728A (en) 1992-03-26
FI895936A7 (en) 1990-06-14
NO894995D0 (en) 1989-12-12
CA2004706A1 (en) 1990-06-13
DK621289A (en) 1990-06-14

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