GB8519418D0 - Indole derivative - Google Patents

Indole derivative

Info

Publication number
GB8519418D0
GB8519418D0 GB858519418A GB8519418A GB8519418D0 GB 8519418 D0 GB8519418 D0 GB 8519418D0 GB 858519418 A GB858519418 A GB 858519418A GB 8519418 A GB8519418 A GB 8519418A GB 8519418 D0 GB8519418 D0 GB 8519418D0
Authority
GB
United Kingdom
Prior art keywords
indole derivative
indole
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB858519418A
Other versions
GB2162522B (en
GB2162522A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848419575A external-priority patent/GB8419575D0/en
Priority claimed from GB848419550A external-priority patent/GB8419550D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GB08519418A priority Critical patent/GB2162522B/en
Publication of GB8519418D0 publication Critical patent/GB8519418D0/en
Publication of GB2162522A publication Critical patent/GB2162522A/en
Priority to MYPI87002751A priority patent/MY102564A/en
Application granted granted Critical
Publication of GB2162522B publication Critical patent/GB2162522B/en
Priority to CY1475A priority patent/CY1475A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08519418A 1984-08-01 1985-08-01 An indole derivative Expired GB2162522B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB08519418A GB2162522B (en) 1984-08-01 1985-08-01 An indole derivative
MYPI87002751A MY102564A (en) 1984-08-01 1987-10-01 An indole derivative
CY1475A CY1475A (en) 1984-08-01 1989-07-21 An indole derivative

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848419575A GB8419575D0 (en) 1984-08-01 1984-08-01 Chemical compounds
GB848419550A GB8419550D0 (en) 1984-08-01 1984-08-01 Automobile invalid seat
GB08519418A GB2162522B (en) 1984-08-01 1985-08-01 An indole derivative

Publications (3)

Publication Number Publication Date
GB8519418D0 true GB8519418D0 (en) 1985-09-04
GB2162522A GB2162522A (en) 1986-02-05
GB2162522B GB2162522B (en) 1988-02-24

Family

ID=27262427

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08519418A Expired GB2162522B (en) 1984-08-01 1985-08-01 An indole derivative

Country Status (2)

Country Link
CY (1) CY1475A (en)
GB (1) GB2162522B (en)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601959D0 (en) * 1986-01-28 1986-03-05 Glaxo Group Ltd Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB2208646B (en) * 1987-08-13 1991-06-26 Glaxo Group Ltd Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
US5155218A (en) 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
CA2043709C (en) * 1990-06-29 2002-01-22 David W. Smith Antimigraine alkoxypyrimidine derivatives
US5077293A (en) * 1990-06-29 1991-12-31 Bristol-Myers Squibb Co. 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
GB9026998D0 (en) * 1990-12-12 1991-01-30 Glaxo Group Ltd Medicaments
US5468504A (en) * 1990-12-21 1995-11-21 Laboratoires Glaxo S.A. Effervescent pharmaceutical compositions
GB9027827D0 (en) * 1990-12-21 1991-02-13 Glaxo Laboratoires Pharmaceutical compositions
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
GB9104890D0 (en) * 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
GB9201038D0 (en) * 1992-01-16 1992-03-11 Glaxo Group Ltd Chemical compounds
FR2686339B1 (en) * 1992-01-22 1994-03-11 Adir Cie NOVEL NAPHTHALENIC AMIDES AND SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9211276D0 (en) * 1992-05-28 1992-07-15 Glaxo Lab Sa Pharmaceutical compositions
EP0574624B1 (en) * 1992-06-17 1997-09-10 Laboratoires Glaxo Sa Pharmaceutical compositions
ES2059236B1 (en) * 1992-06-18 1995-06-16 Imidex S A PROCEDURE FOR THE SYNTHESIS OF 3- (2-DIMETILAMINO) ETIL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE.
ES2055651B1 (en) * 1992-07-20 1995-03-01 Vita Invest Sa PROCEDURE FOR THE OBTAINING OF NEW AMIDINES DERIVED FROM 3-AMINOETILINDOLES.
DE4314976C1 (en) * 1993-05-06 1994-10-06 Lohmann Therapie Syst Lts Transdermal therapeutic systems for the administration of drugs, process for their production and their use
US5382592A (en) * 1993-09-16 1995-01-17 Bristol-Myers Squibb Company Antimigraine cyclobutenedione derivatives of tryptamines
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
US5618816A (en) * 1995-03-02 1997-04-08 Bristol-Myers Squibb Company Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines
AU2104097A (en) * 1996-03-13 1997-10-01 Glaxo Group Limited Medicaments comprising 5ht1-like receptor agonists with an increased absorption
FR2749846B1 (en) * 1996-06-17 1998-09-11 Pf Medicament METHANESULFONATE SALT OF ARYLPIPERAZINE DERIVED FROM TRYPTAMINE AND ITS SOLVATES FOR PHARMACEUTICAL USE
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US6586458B1 (en) 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
AU2003243605A1 (en) * 2002-06-13 2003-12-31 Dr. Reddy's Laboratories Limited 3-'2-(dimethylamino) ethyl!-n-methyl-1h-indole-5-methanesulfonamide and the succinate thereof
MXPA05006954A (en) 2002-12-26 2005-09-22 Pozen Inc Multilayer Dosage Forms Containing NSAIDs and Triptans.
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
WO2004099140A1 (en) * 2003-05-08 2004-11-18 Hetero Drugs Limited Novel crystalline forms of sumatriptan succinate
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
WO2009143571A1 (en) 2008-05-27 2009-12-03 Biota Scientific Management Pty Ltd Antiviral salts
CA2775404C (en) 2009-09-25 2017-01-03 Dr. Reddy's Laboratories Limited Formulations comprising triptan compounds
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
BR112012007087A2 (en) * 2009-09-25 2020-08-11 Dr. Reddy's Laboratoires Limited pharmaceutical compositions comprising triptan compounds and their use for the preparation of a medicament to treat conditions associated with headache
JP7126260B2 (en) 2016-01-27 2022-08-26 インスター テクノロジーズ アクチオヴァ スプルチュノスト Oral Mucosal Nanofiber Carriers for Therapeutic Treatment

Also Published As

Publication number Publication date
GB2162522B (en) 1988-02-24
CY1475A (en) 1989-07-21
GB2162522A (en) 1986-02-05

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Legal Events

Date Code Title Description
CTFF Supplementary protection certificate filed

Free format text: SPC/GB93/071, 930617

CTFA Application for supplementary protection certificate granted

Free format text: SPC/GB93/071, 931005, EXPIRES:20060515

CTFE Supplementary protection certificate entered into force

Free format text: SPC/GB93/071: 20050801, EXPIRES: 20060515

Spc suppl protection certif: SPC/GB93/071

Filing date: 20050801

Expiry date: 20060515

PE20 Patent expired after termination of 20 years

Effective date: 20050731

SPCE Supplementary protection certificate expired

Free format text: SPC/GB93/071:, EXPIRES: 20060515

Spc suppl protection certif: SPC/GB93/071

Expiry date: 20060515