GB851789A - Improvements in or relating to the resolution of tropic acid - Google Patents

Improvements in or relating to the resolution of tropic acid

Info

Publication number
GB851789A
GB851789A GB10912/59A GB1091259A GB851789A GB 851789 A GB851789 A GB 851789A GB 10912/59 A GB10912/59 A GB 10912/59A GB 1091259 A GB1091259 A GB 1091259A GB 851789 A GB851789 A GB 851789A
Authority
GB
United Kingdom
Prior art keywords
resolution
acid
tropic acid
relating
threo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10912/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyesult Gyogyszer es Tapszergyar, Egyt Gyogyszervegyeszeti Gyar filed Critical Egyesult Gyogyszer es Tapszergyar
Publication of GB851789A publication Critical patent/GB851789A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises a process for the resolution of racemic tropic acid by reacting an optically active form of threo-1-(p-nitrophenyl)-2-amino-1:3 propanediol with the tropic acid and separating the resulting diastereoisomeric salts, by difference in solubility thereof, e.g. by treating with a base such as ammonia, and then with an acid such as hydrochloric acid. The compounds D(-) -threo-1-(p nitrophenyl)-2-amino-1:3 propanediol-L(-)-tropate and the corresponding L(+) dextrotatory isomer are described and claimed.
GB10912/59A 1958-03-31 1959-03-31 Improvements in or relating to the resolution of tropic acid Expired GB851789A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851789X 1958-03-31

Publications (1)

Publication Number Publication Date
GB851789A true GB851789A (en) 1960-10-19

Family

ID=10980640

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10912/59A Expired GB851789A (en) 1958-03-31 1959-03-31 Improvements in or relating to the resolution of tropic acid

Country Status (1)

Country Link
GB (1) GB851789A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103387534A (en) * 2012-05-09 2013-11-13 北大方正集团有限公司 Method for separating tropicamide raceme

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103387534A (en) * 2012-05-09 2013-11-13 北大方正集团有限公司 Method for separating tropicamide raceme
CN103387534B (en) * 2012-05-09 2015-02-18 北大方正集团有限公司 Method for separating tropicamide raceme

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