GB849137A - Phenothiazine derivatives and their preparation - Google Patents
Phenothiazine derivatives and their preparationInfo
- Publication number
- GB849137A GB849137A GB26612/58A GB2661258A GB849137A GB 849137 A GB849137 A GB 849137A GB 26612/58 A GB26612/58 A GB 26612/58A GB 2661258 A GB2661258 A GB 2661258A GB 849137 A GB849137 A GB 849137A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- hydroxy
- alkyl
- acyloxysubstituted
- antipyretics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 title 1
- 229940066767 systemic antihistamines phenothiazine derivative Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 abstract 2
- 239000002220 antihypertensive agent Substances 0.000 abstract 2
- 239000002221 antipyretic Substances 0.000 abstract 2
- 229940125716 antipyretic agent Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 229940125723 sedative agent Drugs 0.000 abstract 2
- 239000000932 sedative agent Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- -1 antinanseants Substances 0.000 abstract 1
- 239000002579 antinauseant Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- LKPFBGKZCCBZDK-UHFFFAOYSA-N n-hydroxypiperidine Chemical compound ON1CCCCC1 LKPFBGKZCCBZDK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US680020A US3094526A (en) | 1957-08-23 | 1957-08-23 | 10-[(3-and 4-hydroxy-1-piperidyl) loweralkyl phenothiazines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB849137A true GB849137A (en) | 1960-09-21 |
Family
ID=24729317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB26612/58A Expired GB849137A (en) | 1957-08-23 | 1958-08-19 | Phenothiazine derivatives and their preparation |
Country Status (3)
Country | Link |
---|---|
US (1) | US3094526A (US06623731-20030923-C00052.png) |
BE (1) | BE561550A (US06623731-20030923-C00052.png) |
GB (1) | GB849137A (US06623731-20030923-C00052.png) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3305547A (en) * | 1961-11-25 | 1967-02-21 | Boehringer & Soehne Gmbh | Alkoxypiperidine derivatives and their salts |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1212031A (fr) * | 1957-10-21 | 1960-03-21 | Rhone Poulenc Sa | Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation |
DE1184765B (de) * | 1958-07-07 | 1965-01-07 | Sterling Drug Inc | Verfahren zur Herstellung von 10-Piperidinoalkylphenthiazinderivaten |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2534237A (en) * | 1950-12-19 | B-haloxanthine salts of aminoalkyl | ||
US2838505A (en) * | 1958-06-10 | Ocochzchj | ||
US2645640A (en) * | 1953-07-14 | Phenthiazine derivatives | ||
US2534235A (en) * | 1949-01-19 | 1950-12-19 | Searle & Co | 8-haloxanthine salts of dialkylaminoalkyl type antihistamine bases |
US2676971A (en) * | 1951-04-21 | 1954-04-27 | Searle & Co | Quaternary ammonium derivatives of aminoalkylxanthenes and aminoalkylthiaxanthenes |
US2943086A (en) * | 1955-07-26 | 1960-06-28 | Olin Mathieson | Pharmaceutical compounds |
BE558008A (US06623731-20030923-C00052.png) * | 1956-06-21 |
-
0
- BE BE561550D patent/BE561550A/xx unknown
-
1957
- 1957-08-23 US US680020A patent/US3094526A/en not_active Expired - Lifetime
-
1958
- 1958-08-19 GB GB26612/58A patent/GB849137A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3305547A (en) * | 1961-11-25 | 1967-02-21 | Boehringer & Soehne Gmbh | Alkoxypiperidine derivatives and their salts |
Also Published As
Publication number | Publication date |
---|---|
US3094526A (en) | 1963-06-18 |
BE561550A (US06623731-20030923-C00052.png) |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR002240A1 (es) | Derivado de 2,4-oxazolidinadiona, composicion farmaceutica que lo comprende y metodo de preparacion del mismo. | |
DK499088D0 (da) | 1-oe(2-pyrimidinyl)-aminoalkylaapiperidinderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende saadanne derivater | |
ES431516A1 (es) | Procedimiento para la preparacion de 2-(heterdanilmetilo 5,9-beta-dialcohil-6,7- benzonortanos. | |
SE7714374L (sv) | 1,4-dihydropyridinforbindelser | |
SE8006498L (sv) | Karbostyrilderivat samt forfarande for framstellning av dem | |
FR2404634A1 (fr) | Composes de thiazole et compositions pharmaceutiques en contenant | |
GB849137A (en) | Phenothiazine derivatives and their preparation | |
GB930040A (en) | Improvements in or relating to pyridinium salts | |
ES371297A1 (es) | Procedimiento para la obtencion de 4-ciano-4-fenil-aminoci-clohexanos. | |
FR2410649A1 (fr) | 1-phenyl-2-pyrrolidin-2-yl-ethanols substitues, leur procede de preparation, leurs applications et medicaments les contenant | |
NO158622C (no) | Analogifremgangsmaate for fremstilling av benzosyrederivater med antimikrobiell aktivitet. | |
SE8602524D0 (sv) | Novel quinoline derivatives, pharmaceutical compositions containing them and process for the preparation thereof | |
DE69110217D1 (de) | Derivate der Kaffeinsäure und sie enthaltende pharmazeutische Zusammensetzungen. | |
ES2053755T3 (es) | Un procedimiento para preparar compuestos heterociclicos. | |
ES482138A1 (es) | Procedimiento para la obtencion de 1-bencil -fenil-piperidi-nas. | |
GB843118A (en) | Pharmaceutical compositions containing piperidine derivatives | |
ES481855A1 (es) | Procedimiento para la preparacion de nuevos revidados de 6- metoxi-2-acetilnaftaleno oxima con actividad analgesica. | |
FR2407211A1 (fr) | Nouveaux derives de 3-(1-pyrazolyl)-pyridazine, leurs procedes de preparation et medicaments contenant ces nouveaux derives | |
GB922187A (en) | Phenothiazines and their preparation | |
GB1158473A (en) | Derivatives of Benzothiopyrone and process for preparing them | |
ES445343A1 (es) | Procedimiento para la preparacion de derivados cuaternarios de xantinil-alcohil-nortropina. | |
DK0433167T3 (da) | Hidtil ukendte piperidinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem | |
GB678626A (en) | Improvements in or relating to carbocyanine dyes | |
ES341732A1 (es) | Procedimiento para la produccion de nuevos compuestos orga-nicos relacionados con 1,3-amino alcoholes, sus intermedia- rios y derivados. | |
FR2451380A1 (fr) | Nouveaux derives du dithiepinno (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent |