GB805843A - Collagen strands and method of treating - Google Patents
Collagen strands and method of treatingInfo
- Publication number
- GB805843A GB805843A GB870056A GB870056A GB805843A GB 805843 A GB805843 A GB 805843A GB 870056 A GB870056 A GB 870056A GB 870056 A GB870056 A GB 870056A GB 805843 A GB805843 A GB 805843A
- Authority
- GB
- United Kingdom
- Prior art keywords
- collagen
- solution
- dextran
- strands
- corium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Artificial Filaments (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Abstract
Collagen, from which a strand bonded by dextran is formed, is prepared from kid skin or sheep's intestines. The corium of kid skin is cut into pieces and covered at 10-30 DEG C. with dilute 0.05-0.10 N formic acid solution having a pH of 2-4. After swelling of the corium, excess liquid is drained off and the corium is shredded to facilitate dissolution of collagen. Dissolved collagen is separated under heating and then centrifuged to remove traces of undissolved collagen, hair, &c. The resulting collagen solution is filtered through cotton batting pads. After dissolving the prepared collagen solution in dilute acetic acid, it is extruded through a spinneret into a coagulating and dehydrating bath of ammonium sulphate solution or magnesium sulphate solution buffered with triethanolamine. The resulting strands are passed through a 3 per cent solution of dextran and dried. Sheep's intestines are hydrated in water, split into ribbons, washed in sodium bicarbonate water and scraped clean. Two such ribbons are plied together, tanned in a formaldehyde bath, immersed in dextran solution, spun and dried.ALSO:A surgical suture is formed from a plurality of continuous collagen filaments or a multiplicity of discontinuous collagen fibres which are bonded together by dextran. Collagen, which may be obtained from kid skin by treating with formic acid and is dissolved in acetic acid, is formed into strands by extrusion through a spinneret or long spinning tube into a coagulating and dehydrating bath of ammonium sulphate solution or of magnesium sulphate solution buffered with triethanolamine. The strands, which may then be twisted, are passed through a 3 or 5 per cent solution of B-512 dextran and are then dried under tension. Alternatively, cleaned submucosal ribbons formed by splitting sheep's intestines are plied together, tanned with formaldehyde, immersed in a 5 per cent aqueous solution of B-512 dextran, spun, dried under tension and polished. Dextran may be applied to the strands by spraying. The finished strands are used as sutures or tennis racquet strings.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB870056A GB805843A (en) | 1956-03-20 | 1956-03-20 | Collagen strands and method of treating |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB870056A GB805843A (en) | 1956-03-20 | 1956-03-20 | Collagen strands and method of treating |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB805843A true GB805843A (en) | 1958-12-17 |
Family
ID=9857571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB870056A Expired GB805843A (en) | 1956-03-20 | 1956-03-20 | Collagen strands and method of treating |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB805843A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2129307A (en) * | 1982-10-29 | 1984-05-16 | Jon C Garito | Placement devices for dental splints or retainers |
| EP1674116A2 (en) * | 2004-12-22 | 2006-06-28 | DePuy Products, Inc. | Self-assembling protein matrix prepared from natural extracellular matrices |
| US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
| US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
-
1956
- 1956-03-20 GB GB870056A patent/GB805843A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2129307A (en) * | 1982-10-29 | 1984-05-16 | Jon C Garito | Placement devices for dental splints or retainers |
| US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
| EP1674116A2 (en) * | 2004-12-22 | 2006-06-28 | DePuy Products, Inc. | Self-assembling protein matrix prepared from natural extracellular matrices |
| EP1674116A3 (en) * | 2004-12-22 | 2006-09-06 | DePuy Products, Inc. | Self-assembling protein matrix prepared from natural extracellular matrices |
| US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
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