GB734624A - Bactericidal and similar compositions comprising cellulose ether carrier material - Google Patents

Bactericidal and similar compositions comprising cellulose ether carrier material

Info

Publication number
GB734624A
GB734624A GB4314/53A GB431453A GB734624A GB 734624 A GB734624 A GB 734624A GB 4314/53 A GB4314/53 A GB 4314/53A GB 431453 A GB431453 A GB 431453A GB 734624 A GB734624 A GB 734624A
Authority
GB
United Kingdom
Prior art keywords
water
cellulose ether
ether
cellulose
insoluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4314/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mo och Domsjo AB
Original Assignee
Mo och Domsjo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mo och Domsjo AB filed Critical Mo och Domsjo AB
Publication of GB734624A publication Critical patent/GB734624A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A fungicidal or bactericidal substance which can be dissolved, emulsified or dispersed in water at above 50 DEG C. is applied to a solid cellulose ether, of the type which is soluble in water or aqueous alkali at normal temperature but insoluble in water above 50 DEG C., by treating the solid cellulose ether with a solution, emulsion or dispersion of the substance in water at a temperature at which the cellulose ether is insoluble, preferably 80-100 DEG C. Particularly suitable cellulose ethers are methyl, ethyl, methyl ethyl, methyl hydroxyethyl, ethyl hydroxyethyl, methyl carboxymethyl and ethyl carboxymethyl cellulose. The cellulose ether may be of fibrous structure, and this structure may be maintained during the process. The substances applied to the cellulose ether may be antibiotic materials produced by micro-organisms and which prevent the growth of, or kill, certain other micro-organisms, or such fungicidal, fungistatic, bactericidal, bacteriostatic and virus-killing substances as are not regarded as antibiotics. If the active substance is insoluble in water and difficult to disperse or emulsify therein, even in the presence of emulsifying agents, it may be dissolved in a water-soluble organic solvent, e.g. methanol, ethanol or acetone, and the solution added to a larger volume of water. In certain cases it may be preferable to remove the solvent from the emulsion or dispersion before applying the latter to the cellulose ether. The emulsion or dispersion may be prepared at a temperature below that at which the cellulose ether is insoluble in water and heated, immediately before its application to the cellulose ether, to a temperature above that at which the cellulose ether is insoluble. If the cellulose ether is dry, it may be preheated to about the same temperature as the solution &c., to avoid gel-formation on the surface of the ether due to local cooling of the first added water. The cellulose ether may be a crude product containing salts and other by-products formed during its production, and the process of the invention may then be combined with the step of washing the ether with water near the boiling point without previous drying and possibly grinding of the ether. When the active substance is capable of being adsorbed in the cellulose ether, the washing step may be followed by removal of the waste liquor by filtration or centrifuging, the ether redispersed in hot water, and the aqueous solution &c. of the active material added. When adsorption equilibrium has been established, the water is again removed and the residue dried. When the active substance has no adsorptive affinity for the carrier, the hot moist mass of cellulose ether left after the removal of the wash liquor is sprayed with a hot aqueous solution &c., of the active material and the moist product is dried. The cellulose ether, whether moist or dry, may be sprayed with a solution &c., of the active material in a shredder or kneader simultaneously with mechanical treatment. The solubility of the cellulose ether in water at the operating temperature may be lowered by the addition to the water of water-soluble salts such as sodium fluoride, sodium sulphate or another water-soluble sulphate. In an example, 50 g. of ethylhydroxyethyl cellulose, in which the degrees of substitution with regard to ethyl and hydroxyethyl are about 1.3 and 0.7 respectively, is suspended in boiling water to give an 8 per cent suspension and vacuum filtered to give a mat containing about 50 per cent solids. A solution of 10 g. of lactic acid and 25 g. of sodium lauryl sulphate in 500 ml. of water with pH adjusted to about 3.5 with disodium hydrogen phosphate is poured almost at boiling point over the mat with application of suction. The product is dried and, by defibration, given a loose woollen-like structure.ALSO:A bactericidal or fungicidal substance which can be dissolved, emulsified or dispersed in water at above 50 DEG C. is applied to a solid cellulose ether, of the type which is soluble in water or aqueous alkali at normal temperature but insoluble in water above 50 DEG C., by treating the solid cellulose ether with a solution, emulsion or dispersion of the substance in water at a temperature at which the cellulose ether is insoluble, preferably 80-100 DEG C. Particularly suitable cellulose ethers are methyl, ethyl, methyl ethyl, methyl hydroxyethyl, ethyl hydroxyethyl, methyl carboxymethyl and ethyl carboxymethyl cellulose. The cellulose ether may be of fibrous structure and this structure may be maintained during the process. The substances applied to the cellulose ether may be antibiotic materials produced by micro-organisms and which prevent the growth of, or kill, certain other micro-organisms, or such fungicidal, fungistatic, bactericidal, bacteriostatic and virus-killing substances as are not regarded as antibiotics. If the active substance is insoluble in water and difficult to disperse or emulsify therein, even in the presence of emulsifying agents, it may be dissolved in a water-soluble organic solvent, e.g. methanol, ethanol or acetone, and the solution added to a larger volume of water. In certain cases it may be preferable to remove the solvent from the emulsion or dispersion before applying the latter to the cellulose ether. The emulsion or dispersion may be prepared at a temperature below that at which the cellulose ether is insoluble in water and heated, immediately before its application to the cellulose ether, to a temperature above that at which the cellulose ether is insoluble. If the cellulose ether is dry it may be preheated to about the same temperature as the solution &c. to avoid gel-formation on the surface of the ether due to local cooling of the first added water. The cellulose ether may be a crude product containing salts and other by-products formed during its production, and the process of the invention may then be combined with the step of washing the ether with water near the boiling point without previous drying and possibly grinding of the ether. When the active substance is capable of being adsorbed on the cellulose ether, the washing step may be followed by removal of the wash liquor by filtration or centrifuging, the ether redispersed in hot water, and the aqueous solution &c. of the active material added. When adsorption equilibrium has been established, the water is again removed and the residue dried. When the active substance has no adsorptive affinity for the carrier, the hot moist mass of cellulose ether left after the removal of the wash liquor is sprayed with a hot aqueous solution &c. of the active material and the moist product is dried. The cellulose ether, whether moist or dry, may be sprayed with a solution, &c. of the active material in a shredder or kneader simultaneously with mechanical treatment. The solubility of the cellulose ether in water at the operating temperature may be lowered by the addition to the water of water-soluble salts such as sodium fluoride, sodium sulphate or another water-soluble sulphate. In an example, 50 g. of ethylhydroxyethyl cellulose, in which the degrees of substitution with regard to ethyl and hydroxyethyl are about 1.3 and 0.7 respectively, is suspended in boiling water to give an 8 per cent suspension and vacuum-filtered to give a mat containing about 50 per cent solids. A solution of 10 g. of lactic acid and 25 g. of sodium lauryl sulphate in 500 ml. of water with pH adjusted to about 3.5 with disodium hydrogen phosphate, is poured almost at boiling point over the mat with application of suction. The product is dried and, by defibration, given a loose woollen-like structure.
GB4314/53A 1952-11-21 1953-02-16 Bactericidal and similar compositions comprising cellulose ether carrier material Expired GB734624A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE734624X 1952-11-21

Publications (1)

Publication Number Publication Date
GB734624A true GB734624A (en) 1955-08-03

Family

ID=20319642

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4314/53A Expired GB734624A (en) 1952-11-21 1953-02-16 Bactericidal and similar compositions comprising cellulose ether carrier material

Country Status (1)

Country Link
GB (1) GB734624A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2887440A (en) * 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
US2890151A (en) * 1956-02-23 1959-06-09 Cleveland J White Therapeutic composition comprising powdered maize cob
EP0121712A1 (en) * 1983-03-03 1984-10-17 The Dow Chemical Company Sustained release compositions from cellulose ethers
EP0145846A2 (en) * 1983-12-01 1985-06-26 ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) Polyhdroxy polymer delivery system
US9750755B2 (en) 2006-09-08 2017-09-05 Delaval Holding Ab Antimicrobial compositions and related methods

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2890151A (en) * 1956-02-23 1959-06-09 Cleveland J White Therapeutic composition comprising powdered maize cob
US2887440A (en) * 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
EP0121712A1 (en) * 1983-03-03 1984-10-17 The Dow Chemical Company Sustained release compositions from cellulose ethers
AU569277B2 (en) * 1983-03-03 1988-01-28 Dow Chemical Company, The Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents
EP0145846A2 (en) * 1983-12-01 1985-06-26 ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) Polyhdroxy polymer delivery system
EP0145846A3 (en) * 1983-12-01 1987-11-19 Pennwalt Corporation Polyhdroxy polymer delivery system
US9750755B2 (en) 2006-09-08 2017-09-05 Delaval Holding Ab Antimicrobial compositions and related methods

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