GB678589A - Improvements in the synthesis of beta-phenylethyl alcohol - Google Patents
Improvements in the synthesis of beta-phenylethyl alcoholInfo
- Publication number
- GB678589A GB678589A GB10498/50A GB1049850A GB678589A GB 678589 A GB678589 A GB 678589A GB 10498/50 A GB10498/50 A GB 10498/50A GB 1049850 A GB1049850 A GB 1049850A GB 678589 A GB678589 A GB 678589A
- Authority
- GB
- United Kingdom
- Prior art keywords
- styrene oxide
- phenylethyl alcohol
- palladium
- platinum
- alkali metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
b -Phenylethylalcohol is prepared by a method which comprises subjecting styrene oxide in liquid phase to the action of hydrogen at room or ambient temperature and moderately super-atmospheric pressure in the presence of a hydrogenation catalyst and a low alkanol which is a solvent for the styrene oxide and resulting b -phenyl ethyl alcohol and thereby effecting conversion of the styrene oxide to b -phenylethyl alcohol. Hydrogenation catalysts mentioned include nickel, e.g. in the form of Raney nickel, palladium or platinum and compounds of palladium and platinum. Preferably the reaction is carried out in the presence of an alkaline-reacting material which suppresses catalyst poisoning caused for example by thiophenic impurities in the styrene oxide. Preferred alkaline reacting materials include alkali metal hydroxide such as sodium hydroxide though alkali metal carbonates such as sodium carbonate may be used. The reaction may be carried out by a batch or continuous process. In examples styrene oxide in ethyl alcohol solution in the presence of sodium hydroxide and Raney nickel is treated with hydrogen under pressure at room temperature. The product is neutralized with hydrochloric acid and extracted with ether and b -phenylethyl alcohol is separated by distillation. Specification 320,424, [Class 2 (iii)], is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US678589XA | 1949-06-18 | 1949-06-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB678589A true GB678589A (en) | 1952-09-03 |
Family
ID=22078896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB10498/50A Expired GB678589A (en) | 1949-06-18 | 1950-04-28 | Improvements in the synthesis of beta-phenylethyl alcohol |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB678589A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2794055A (en) * | 1957-05-28 | Catalytic hydrogenation of styrene | ||
| US2822403A (en) * | 1954-12-07 | 1958-02-04 | Pittsburgh Coke & Chemical Co | Process for the preparation of beta-phenyl ethyl alcohol |
| US4943667A (en) * | 1988-01-16 | 1990-07-24 | Basf Aktiengesellschaft | Preparation of phenylethanols |
| US6166269A (en) * | 1998-12-24 | 2000-12-26 | Council Of Scientific And Industrial Resesearch | Process for the preparation of 2-phenyl ethanol |
| US9040755B2 (en) | 2011-12-15 | 2015-05-26 | Council Of Scientific And Industrial Research | Hydrogenation of styrene oxide forming 2-phenyl ethanol |
-
1950
- 1950-04-28 GB GB10498/50A patent/GB678589A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2794055A (en) * | 1957-05-28 | Catalytic hydrogenation of styrene | ||
| US2822403A (en) * | 1954-12-07 | 1958-02-04 | Pittsburgh Coke & Chemical Co | Process for the preparation of beta-phenyl ethyl alcohol |
| US4943667A (en) * | 1988-01-16 | 1990-07-24 | Basf Aktiengesellschaft | Preparation of phenylethanols |
| US6166269A (en) * | 1998-12-24 | 2000-12-26 | Council Of Scientific And Industrial Resesearch | Process for the preparation of 2-phenyl ethanol |
| US9040755B2 (en) | 2011-12-15 | 2015-05-26 | Council Of Scientific And Industrial Research | Hydrogenation of styrene oxide forming 2-phenyl ethanol |
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