GB667010A - Process for the production of preparations intended for medicinal injection - Google Patents

Process for the production of preparations intended for medicinal injection

Info

Publication number
GB667010A
GB667010A GB2885/50A GB288550A GB667010A GB 667010 A GB667010 A GB 667010A GB 2885/50 A GB2885/50 A GB 2885/50A GB 288550 A GB288550 A GB 288550A GB 667010 A GB667010 A GB 667010A
Authority
GB
United Kingdom
Prior art keywords
drug
salol
thymol
mixtures
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2885/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Publication of GB667010A publication Critical patent/GB667010A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

667,010. Medicines for injection. NAAMLOOZE VENNOOTSCHAP ORGANON. Feb. 3, 1950 [Feb. 18, 1949], No. 2885/50. Drawings to Specification. Class 81 (i). A medicine for injection is prepared from a sparingly water-soluble or water-insoluble drug by making an aqueous emulsion of a solution of the drug in an organic solvent, the solvent having a great dissolving capacity for the drug but a limited solubility in aqueous liquids although far exceeding that of the drug, and the concentration of the drug in the solvent being such that on dilution of the emulsion with water a separation of the drug in solid form occurs. Specified drugs are testosterone propionate, progesterone, desoxycorticosterone or its acetate, oestradiol benzoate, and stilboesterol. Specified organic solvents are benzyl alcohol, mixtures of benzyl alcohol with salol or thymol, mixtures of salol and thymol, and mixtures of camphor with salol, thymol or menthol. Emulsifying agents such as polyoxy alkylene derivatives of hexitol mono-esters of higher fatty acids, sodium longchain alkylsulphates, triethanol aminocaseinate and Turkey red oil may be added. These emulsions may be sterilized by heat in the ampoules containing them. The order in which the components of the emulsion are mixed may be varied. Specification 417,715 is referred to.
GB2885/50A 1949-02-18 1950-02-03 Process for the production of preparations intended for medicinal injection Expired GB667010A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL667010X 1949-02-18

Publications (1)

Publication Number Publication Date
GB667010A true GB667010A (en) 1952-02-20

Family

ID=19798782

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2885/50A Expired GB667010A (en) 1949-02-18 1950-02-03 Process for the production of preparations intended for medicinal injection

Country Status (2)

Country Link
GB (1) GB667010A (en)
NL (2) NL69010C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1140667B (en) * 1961-06-28 1962-12-06 Schering Ag Process for the production of highly concentrated steroid solutions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1140667B (en) * 1961-06-28 1962-12-06 Schering Ag Process for the production of highly concentrated steroid solutions

Also Published As

Publication number Publication date
NL144941B (en)
NL69010C (en)

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