GB613030A - A process for working up the pancreas of mammals - Google Patents
A process for working up the pancreas of mammalsInfo
- Publication number
- GB613030A GB613030A GB24961/45A GB2496145A GB613030A GB 613030 A GB613030 A GB 613030A GB 24961/45 A GB24961/45 A GB 24961/45A GB 2496145 A GB2496145 A GB 2496145A GB 613030 A GB613030 A GB 613030A
- Authority
- GB
- United Kingdom
- Prior art keywords
- exceeding
- hours
- extraction
- pancreas
- mammals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Trypsin and other exogenously secreted enzymes are extracted from the pancreas of mammals, more especially of horned cattle or pigs, by treating the disintegrated fresh or preserved glands with an acidulated aqueous medium at a relatively low temperature not exceeding 25 DEG C. and/or within a relatively short extraction period not exceeding 24 hours. Optimum extraction occurs with a pH or 1-4, preferably 2, extraction time of 2 hours, preferably 1/2 hour, and a temperature of approximately 0 DEG C.ALSO:Insulin may be extracted from the pancreas of mammals, more especially of horned cattle and pigs, by first extracting trypsin and other exogenously secreted enzymes from the disintegrated fresh or preserved glands by means of an acidulated aqueous medium at a relatively low temperature not exceeding 25 DEG C and/or p within a relatively short extraction period not exceeding 24 hours and then extracting the insulin in a manner known per the residue so obtained. Optimum enzyme extraction occurs with a pH of 1-4, preferably 2, an extraction time of 2 hours, preferably 1/2 -hour, and a temperature of approximately 0 DEG C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE613030X | 1941-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB613030A true GB613030A (en) | 1948-11-22 |
Family
ID=6576498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24961/45A Expired GB613030A (en) | 1941-04-09 | 1945-09-26 | A process for working up the pancreas of mammals |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB613030A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2686148A (en) * | 1951-11-30 | 1954-08-10 | Armour & Co | Recovery of proteolytic enzymes from pancreas gland residues subsequent to insulin removal |
-
1945
- 1945-09-26 GB GB24961/45A patent/GB613030A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2686148A (en) * | 1951-11-30 | 1954-08-10 | Armour & Co | Recovery of proteolytic enzymes from pancreas gland residues subsequent to insulin removal |
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