GB2619405B - Mass spectrometry - Google Patents

Mass spectrometry Download PDF

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Publication number
GB2619405B
GB2619405B GB2305360.6A GB202305360A GB2619405B GB 2619405 B GB2619405 B GB 2619405B GB 202305360 A GB202305360 A GB 202305360A GB 2619405 B GB2619405 B GB 2619405B
Authority
GB
United Kingdom
Prior art keywords
mass spectrometry
spectrometry
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2305360.6A
Other versions
GB2619405A (en
GB202305360D0 (en
Inventor
Eder Mosedale David
Sharp Tilly
John Grainger David
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Methuselah Health Uk Ltd
Original Assignee
Methuselah Health Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methuselah Health Uk Ltd filed Critical Methuselah Health Uk Ltd
Priority to GB2305360.6A priority Critical patent/GB2619405B/en
Publication of GB202305360D0 publication Critical patent/GB202305360D0/en
Publication of GB2619405A publication Critical patent/GB2619405A/en
Application granted granted Critical
Publication of GB2619405B publication Critical patent/GB2619405B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/4245—Electrostatic ion traps
    • H01J49/425—Electrostatic ion traps with a logarithmic radial electric potential, e.g. orbitraps

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB2305360.6A 2023-04-12 2023-04-12 Mass spectrometry Active GB2619405B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2305360.6A GB2619405B (en) 2023-04-12 2023-04-12 Mass spectrometry

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2305360.6A GB2619405B (en) 2023-04-12 2023-04-12 Mass spectrometry

Publications (3)

Publication Number Publication Date
GB202305360D0 GB202305360D0 (en) 2023-05-24
GB2619405A GB2619405A (en) 2023-12-06
GB2619405B true GB2619405B (en) 2024-05-08

Family

ID=86378800

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2305360.6A Active GB2619405B (en) 2023-04-12 2023-04-12 Mass spectrometry

Country Status (1)

Country Link
GB (1) GB2619405B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004090933A2 (en) * 2003-04-09 2004-10-21 Mds Inc. Doing Business Through Its Mds Sciex Division Dynamic signal selection in chromatography/mass spectrometry/mass spectrometry system
GB2559395A (en) * 2017-02-03 2018-08-08 Thermo Fisher Scient Bremen Gmbh High resolution MS1 based quantification
EP4047371A1 (en) * 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004090933A2 (en) * 2003-04-09 2004-10-21 Mds Inc. Doing Business Through Its Mds Sciex Division Dynamic signal selection in chromatography/mass spectrometry/mass spectrometry system
GB2559395A (en) * 2017-02-03 2018-08-08 Thermo Fisher Scient Bremen Gmbh High resolution MS1 based quantification
EP4047371A1 (en) * 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Journal of Proteome Research, vol. 19, no. 8, Fernandez-Costa et al., "Impact of the Identification Strategy on the Reproducibility of the DDA and DIA Results", p. 3153-3161. Available from: https://doi.org/10.1021/acs.jproteome.0c00153 *
Molecular Systems Biology, vol. 4, 2008, Vinzenz et al., "Selected reaction monitoring for quantitative proteomics: a tutorial", pages 1-14. Available from http://dx.doi.org/10.1038/msb.2008.61 *
Scientific Reports, vol. 6, Zhang et al., "Fast MS/MS acquisition without dynamic exclusion enables precise and accurate quantification of proteome by MS/MS fragment intensity", Article No.: 26392, pages 1-9. Available from: http://dx.doi.org/10.1038/srep26392 *

Also Published As

Publication number Publication date
GB2619405A (en) 2023-12-06
GB202305360D0 (en) 2023-05-24

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