GB2611573A - Method and device for cooling comprising element - Google Patents
Method and device for cooling comprising element Download PDFInfo
- Publication number
- GB2611573A GB2611573A GB2114468.8A GB202114468A GB2611573A GB 2611573 A GB2611573 A GB 2611573A GB 202114468 A GB202114468 A GB 202114468A GB 2611573 A GB2611573 A GB 2611573A
- Authority
- GB
- United Kingdom
- Prior art keywords
- peltier element
- cooling
- side wall
- interspace
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000001816 cooling Methods 0.000 title claims abstract description 55
- 238000000034 method Methods 0.000 title claims abstract description 14
- 239000002274 desiccant Substances 0.000 claims abstract description 22
- 238000007789 sealing Methods 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 3
- 238000009413 insulation Methods 0.000 abstract description 5
- 230000001351 cycling effect Effects 0.000 abstract description 3
- 238000003752 polymerase chain reaction Methods 0.000 abstract description 3
- 239000003570 air Substances 0.000 description 10
- 239000012080 ambient air Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002937 thermal insulation foam Substances 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B21/00—Machines, plants or systems, using electric or magnetic effects
- F25B21/02—Machines, plants or systems, using electric or magnetic effects using Peltier effect; using Nernst-Ettinghausen effect
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
- B01L2300/105—Means to control humidity and/or other gases using desiccants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B2321/00—Details of machines, plants or systems, using electric or magnetic effects
- F25B2321/02—Details of machines, plants or systems, using electric or magnetic effects using Peltier effects; using Nernst-Ettinghausen effects
- F25B2321/023—Mounting details thereof
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A cooling device and a method of cooling comprises a Peltier element 9 thermally connected to a cold plate 2 by both being in contact with a cooling block 15, with both the Peltier element and cooling block being surrounded by an interspace 16 that is sealed with a housing. The housing comprises a side wall 11 between the cold plate and a Peltier heat sink 17 which is arranged below the Peltier element, and wherein the side wall surrounds the Peltier element and cooling block. An opening 13 may be located in the side wall and connected to a vacuum pump for evacuating the interspace to enhance insulation. The interspace may be flushed with dehumidified air. A second opening in the housing may be provided and is part of a closed air circuit between the interspace and a pump 23 (fig 2). The circuit may comprise a replaceable desiccant cartridge 21 to dry circulated air. The device prevents moisture reaching the Peltier element and protects it from damage / failure by exposure to condensate or moisture. An automated analyser system used in clinical diagnostics and life sciences may use the device, for example temperature cycling for polymerase chain reaction.
Description
METHOD AND DEVICE FOR COOLING COMPRISING ELEMENT
DESCRIPTION
Field of the Invention
[0001] The invention relates to a device, a system comprising the device, and a method for cooling comprising a Peltier element.
Brief description of the related art
[0002] Automated analyser systems for use in clinical diagnostics and life sciences are produced by a number of companies For example, STRATECk SE, Birkenfeld, Germany, produces a number of devices for specimen handling and detection for use in automated analyser systems and other laboratory instrumentation.
[0003] STRATEC' designs and manufactures in vitro diagnostic devices which are capable of changing temperatures in container comprising liquids which are biochemically processed. In such thermoelectric devices, so-called Peltier elements are used wherever temperature cycling between cooling and heating is advantageous. Peltier elements can also be used for cooling or heating only. Examples of applications are in thermal cyclers for temperature cycling of samples e.g. for the polymerase chain reaction (PCR), as well as the cooling of reagent containers in the loading area of an automated analyzer system like a diagnostic device [0004] A Peltier element generates a temperature difference when current flows through it, which can be used in many ways for cooling or heating Condensate accumulates on the cooling side when Peltier elements are used for cooling. This condensate is not only on the application side, but also directly on the Peltier element itself [0005] According to the state of the art, foam, insulation foam or sealing of the Peltier element by an additional sealing compound is used to shield the cold surfaces from (moistened) ambient air. This does not reliably prevent the accumulation of condensation moisture. Failing Peltier elements due to moisture will still remain a problem.
[0006] In other embodiments known in the prior art, the installed Peltier elements themselves are sealed against moisture penetration (by epoxy resins or polyurethane sealing compounds), but these seals are not durable to date. Penetrating moisture first leads to a reduced cooling capacity and in the long run to the failure of the affected module.
[0007] Because the used (sealing) materials (e.g. foam, silicone, etc.) do not hermetically seal, condensate may also enter the area of the Peltier elements from other places due to the capillary effect.
[0008] An additional sealing compound on an assembled ready-to-install assembly is implemented as a preventive measure, but this is quite costly and variable due to a manual process. Even this process does not provide permanent protection against moisture penetration.
Object of the Invention 100091 It is therefore the object of this invention to provide a device and a method for protecting Peltier elements from condensates or moisture.
Summary of the Invention
[0010] The present invention provides a device for cooling, comprising a Peltier element and a cold plate, which are connected thermally by both being in contact with a cooling block, wherein Peltier element and cooling block are surrounded by an interspace that is sealed with a housing formed by a side wall that is arranged between cold plate and a Peltier heat sink arranged below the Peltier element, wherein the side wall surrounds Peltier element and cooling block.
[0011] In a further aspect of the present invention, the side wall may comprise a first opening [0012] The housing may be sealed against the exterior with 0-rings arranged between side wall and cold plate and between side wall and Peltier heat sink, respectively, for shielding Peltier element and cooling block from the surrounding environment in a further embodiment of the present invention.
[0013] It may further be envisaged that the first opening of the housing is connected to a vacuum pump.
[0014] The invention relates further to an embodiment where the housing comprises a second opening.
[0015] It may also be intended that first and second opening of the housing are part of a closed air circuit between interspace and a pump.
[0016] In another aspect of the invention, the closed air circuit may further comprise a desiccant cartridge.
[0017] Another embodiment of the invention relates to a device, wherein the desiccant comprised in the desiccant cartridge changes its color depending on the degree of saturation with moisture.
[0018] Another object of the present invention relates to an automated analyser system comprising a device as described in the previous paragraphs.
[0019] The invention relates further to a system, wherein the device for cooling has an application side for cooling container that are placed on said application side [0020] Another object of the present invention relates to a method for cooling, comprising the steps of providing a cold plate and a Peltier element which are connected both by being in contact with a cooling block, wherein an interspace surrounds Peltier element and cooling block; - sealing the interspace with a side wall that surrounds Peltier element and cooling block and is in contact with the cold plate on one side and a Peltier heat sink arranged below the Peltier element, wherein the side wall has a first opening; - applying a vacuum to the interspace through the first opening in the housing which is connected to a vacuum pump.
[0021] For performing the method, the housing can be sealed against the exterior with 0-rings between the side wall and cold plate and side wall and Peltier heat sink.
[0022] The method may further comprise the step of drying the air in the interspace with a desiccant.
[0023] Still other aspects, features, and advantages of the present invention are readily apparent from the following detailed description, simply by illustrating preferable embodiments and implementations. The present invention is also capable of other and different embodiments and its several details can be modified in various obvious respects, all without departing from the spirit and scope of the present invention. Accordingly, the drawings and descriptions are to be regarded as illustrative in nature, and not as restrictive. Additional objects and advantages of the invention will be set forth in part in the description which follows and in part will be obvious from the description, or may be learned by practice of the invention.
Summary of the Figures
[0024] The invention will be described based on figures. It will be understood that the embodiments and aspects of the invention described in the figures are only examples and do not limit the protective scope of the claims in any way. The invention is defined by the claims and their equivalents. It will be understood that features of one aspect or embodiment of the invention can be combined with a feature of a different aspect or aspects of other embodiments of the invention, in which: [0025] FIG. 1 shows an embodiment with a hermetically sealed interspace surrounding a cooling block which transfer the cooling from the Peltier element to the cold plate.
[0026] FIG. 2 shows an embodiment using additionally a desiccant cartridge.
Detailed Description of the Invention and the Figures [0027] The technical problem is solved by the independent claims The dependent claims cover further specific embodiments of the invention.
[0028] The following disclosure refers to a cold plate for applying or arranging samples or carrier onto it comprising container with samples. Said cold plate is connected in terms of temperature transfer to a Peltier element via a cooling block. The surface or side of the cold plate that is in contact with the cooling block is designates as the cooling side. The cold plate "separates" the application from the arrangement comprising the Peltier element for cooling it. The side of the cold plate which is used to cool goods in or during an application is defined as the application side.
[0029] FIG. I shows the cold plate 2 wherein the upper surface is the application side 5. The lower side of the cold plate 2 is the cooling side 7. Condensate forms on both sides (application and cooling side 5, 7) of cold plate 2, so that not only the application side 5 but also the Peltier element 9 itself is affected by the condensate. Cooling block 15 is arranged between Peltier element 9 and cold plate 2 and is in contact with both elements to transfer cooling from the Peltier element 9 to cold plate 2.
[0030] A factory sealing of the Peltier element 9 does often not provide a permanent seal, so that the active power of the Peltier element 9 can be directly affected by the produced condensate and can lead to a failure of the Peltier element 9. To reduce a Peltier element 9 failure and to increase a Peltier element's 9 life expectancy and reliability, the Peltier element 9 is sealed/insulated from any liquids so that condensates like moisture cannot reach the Peltier element 9.
[0031] The device and method according to the present disclosure intends to avoid moisture reaching the Peltier element and they are based on a hermetic sealing of the Peltier element 9 against the environment is achieved via a housing or enclosure which is formed by a side wall 11, cold plate 2 and the upper surface of Peltier heat sink 17; an opening 13 in side wall 11 surrounding Peltier element 9 and cooling block 15 for evacuating the interspace 16 surrounding cooling block 15 and Peltier element 9 to enhance the insulation effect; optional "flushing" of the interspace 16 with dehumidified air.
[0032] Condensation can be avoided by moisture-proof shielding of the Peltier element 9 against the environment and additionally by removal of the air humidity through an opening 13 of the housing which seals the interspace 16 surrounding cooling block 15 and Peltier element 9 which are arranged between cold plate 2 and Peltier heat sink 17. FIG. 1 shows an embodiment according to the present disclosure. For a hermetic sealing, the Peltier element 9 and cooling block 15 are surrounded by side wall 11 for shielding them from the environment. 0-rings 19 may be arranged between side wall 11 and cold plate 2 and between side wall 11 and Peltier heat sink 17, respectively. The side wall may have a round or rectangular shape in a top or bottom view.
[0033] The housing is usually easily implemented by arranging the side wall 11 between cold plate 2 and Peltier heat sink 17. By an additional application of a vacuum via e.g. a vacuum pump (not shown), a negative pressure can be applied to the interspace 16 surrounding Peltier element 9 and cooling block 15, so that potentially existing humidity will be removed by forced evaporation (boiling point lowering). It is beneficial to have a vacuum-tight electrical feed-through of the electrical lines (not shown) for the connection of the Peltier elements 9.
[0034] It is an advantage that through sealing and evacuation, moisture will no longer reach the Peltier elements, so that no oxidation and no oxidation-related failure of the device will occur.
[0035] Another advantage relates to the fact that the vacuum provides an improved "insulation effect" (thermal insulation) in comparison to using foam for insulation, so that a better efficiency will be obtained Any additional costs related to the sealing of the Peltier elements will pay off through an increased reliability of the entire device, as well as through reduced service efforts and service costs.
[0036] An alternative approach relates to an embodiment comprising the sealing of the Peltier element from the ambient air with a tight cable bushing and without connections of e.g. a pump to generate negative or positive pressure. The hermetically sealed interspace around Peltier element and cooling block can be filled with either ambient air or dried air.
[0037] Alternatively, a desiccant may be added to the sealed interspace. This option is a simple alternative when humidity needs to be reduced. It also reduces costs by only sealing through an enclosure. The disadvantage of this option can be that leaks will still be possible, and a small amount of moisture can still be present or remain on the Peltier element.
[0038] Another alternative relates to a design which is less sensitive to leaks. Basically, the setup described above can also be used to pressurize the system with overpressure, e.g. with dried air. In such an application, the system is not pressurized with negative pressure, but positive pressure is generated by reversing the direction of a vacuum pump. Instead of evacuating the moisture, positive pressure is built up, e.g. with dried air to remove the moisture.
[0039] FIG. 2 shows an embodiment comprising a closed air circuit comprising a pump 23 so that air circulation with drying is achieved by using a desiccant cartridge 21. When the desiccant cartridge 21 is saturated, a new desiccant cartridge must be inserted. A color change may be used to indicate that the desiccant cartridge 21 or its content, the desiccant, has to be exchanged.
[0040] Another embodiment relates to the use of a desiccant cartridge that is installed within the housing via a screw-in opening. The status of a color change in the desiccant cartridge, for example, can be used for determining via a viewing window the status of the desiccant. The granules may change their color when moisture has been absorbed and the color change indicates the amount of moisture that has been absorbed. When the desiccant cartridge is saturated, a new desiccant cartridge is inserted via the screw-in opening to absorb liquid again. This option can be used and monitored individually for each Peltier element.
[0041] The foregoing description of the preferred embodiment of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise form disclosed, and modifications and variations are possible in light of the above teachings or may be acquired from practice of the invention. The embodiment was chosen and described in order to explain the principles of the invention and its practical application to enable one skilled in the art to utilize the invention in various embodiments as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims appended hereto, and their equivalents. The entirety of each of the aforementioned documents is incorporated by reference herein.
Reference Numerals 2 cold plate application side 7 cooling side 9 Peltier element 11 side wall 13 opening cooling block 16 interspace 17 Peltier heat sink 19 0-ring 21 desiccant cartridge 23 pump
Claims (13)
-
- A device for cooling, comprising a Peltier element and a cold plate, which are connected thermally by both being in contact with a cooling block, wherein Peltier element and cooling block are surrounded by an interspace that is sealed with a housing formed by a side wall that is arranged between cold plate and a Peltier heat sink arranged below the Peltier element, wherein the side wall surrounds Peltier element and cooling block.
- The device of claim I, wherein the side wall comprises a first opening The device of claim 1 or 2, wherein the housing is sealed against the exterior with 0-rings arranged between side wall and cold plate arid between side wail and Peltier heat sink, respectively, for shielding Peltier element and cooling block from the surrounding environment.
- The device of any one of claims 1 to 3, wherein the first opening of the housing is connected to a vacuum pump.
- The device of any one of claims 1 to 4, wherein the housing comprises a second opening.
- The device of claim 5, wherein first and second opening of the housing are part of a closed air circuit between interspace and a pump.
- The device of claim 6, wherein the closed air circuit further comprises a desiccant cartridge.
- The device of claim 7, wherein the desiccant comprised in the desiccant cartridge changes its color depending on the degree of saturation with moisture.
- An automated analyser system comprising a device according to any one of claims 1 to 8 for cooling.
- 10. The system of claim 9, wherein the device for cooling has an application side for cooling container that are placed on said application side.
- 11. A method for cooling, comprising the steps of - providing a cold plate and a Peltier element which are connected both by being in contact with a cooling block, wherein an interspace surrounds Peltier element and cooling block; - sealing the interspace with a side wall that surrounds Peltier element and cooling block and is in contact with the cold plate on one side and a Peltier heat sink arranged below the Peltier element, wherein the side wall has a first opening; - applying a vacuum to the interspace through the first opening in the housing which is connected to a vacuum pump.
- 12. The method of claim 11, wherein the housing is sealed against the exterior with 0-rings between the side wall and cold plate and side wall and Peltier heat sink.
- 13. The method of claim 11 or 12, comprising the step of drying the air in the interspace with a desiccant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2114468.8A GB2611573A (en) | 2021-10-11 | 2021-10-11 | Method and device for cooling comprising element |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2114468.8A GB2611573A (en) | 2021-10-11 | 2021-10-11 | Method and device for cooling comprising element |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB202114468D0 GB202114468D0 (en) | 2021-11-24 |
| GB2611573A true GB2611573A (en) | 2023-04-12 |
Family
ID=78595085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2114468.8A Withdrawn GB2611573A (en) | 2021-10-11 | 2021-10-11 | Method and device for cooling comprising element |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2611573A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070157628A1 (en) * | 2006-01-11 | 2007-07-12 | Yamaha Corporation | Temperature control apparatus |
| US10808971B2 (en) * | 2016-08-12 | 2020-10-20 | Te Technology, Inc. | Thermoelectric assembly sealing member with metal vapor barrier |
| US10865440B2 (en) * | 2011-10-21 | 2020-12-15 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
| US20210041379A1 (en) * | 2018-03-12 | 2021-02-11 | The Penn State Research Foundation | Method and apparatus for temperature gradient microfluidics |
-
2021
- 2021-10-11 GB GB2114468.8A patent/GB2611573A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070157628A1 (en) * | 2006-01-11 | 2007-07-12 | Yamaha Corporation | Temperature control apparatus |
| US10865440B2 (en) * | 2011-10-21 | 2020-12-15 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
| US10808971B2 (en) * | 2016-08-12 | 2020-10-20 | Te Technology, Inc. | Thermoelectric assembly sealing member with metal vapor barrier |
| US20210041379A1 (en) * | 2018-03-12 | 2021-02-11 | The Penn State Research Foundation | Method and apparatus for temperature gradient microfluidics |
Also Published As
| Publication number | Publication date |
|---|---|
| GB202114468D0 (en) | 2021-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |