GB2587550A - Transcutaneous port and method for manufacture - Google Patents

Transcutaneous port and method for manufacture Download PDF

Info

Publication number
GB2587550A
GB2587550A GB2017441.3A GB202017441A GB2587550A GB 2587550 A GB2587550 A GB 2587550A GB 202017441 A GB202017441 A GB 202017441A GB 2587550 A GB2587550 A GB 2587550A
Authority
GB
United Kingdom
Prior art keywords
port
transcutaneous
mesh
port according
port body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB2017441.3A
Other versions
GB202017441D0 (en
GB2587550B (en
Inventor
Armstrong James
Agg Philip
Merotra James
Shawcross James
Prendegrass Catherine
Blunn Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accentus Cardiac Ltd
UCL Business Ltd
Original Assignee
Accentus Cardiac Ltd
UCL Business Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accentus Cardiac Ltd, UCL Business Ltd filed Critical Accentus Cardiac Ltd
Publication of GB202017441D0 publication Critical patent/GB202017441D0/en
Publication of GB2587550A publication Critical patent/GB2587550A/en
Application granted granted Critical
Publication of GB2587550B publication Critical patent/GB2587550B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
    • A61F5/445—Colostomy, ileostomy or urethrostomy devices
    • A61F2005/4455—Implantable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0261—Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0273—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body for introducing catheters into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0279—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body for introducing medical instruments into the body, e.g. endoscope, surgical tools
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0285—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body with sterilisation means, e.g. antibacterial coatings, disinfecting pads, UV radiation LEDs or heating means in the port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0291—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body method or device for implanting it in the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention provides a transcutaneous port which promotes tissue integration for anchoring in the skin and which reduces the risk of infection. The transcutaneous port of the invention comprises a port body (1) having an external end (2a) and a subcutaneous end (2b) and at least one channel (5) which extends longitudinally through the port body. The port body (1) comprises a first impermeable portion (3) extending longitudinally from the external end (2a) and a mesh portion (4) extending longitudinally from the subcutaneous end (2b) of the port body (1). The thickness of the mesh portion (4) has a smaller thickness T1 proximate to the first impermeable portion (3) of the port body (1) and a larger thickness T2 proximate to the subcutaneous end (2b) of the port body (1). The thicker part of the mesh portion (4) is suitable for contacting the dermis when the transcutaneous port is implanted. The invention further relates to a method of manufacturing the transcutaneous port and a method of implanting the port in the human or animal body.

Claims (29)

1. A transcutaneous port comprising: a port body (1) having an external end (2a) and a subcutaneous end (2b); and at least one channel (5) which extends longitudinally through the port body (1) from the external end (2a) to the subcutaneous end (2b); wherein the port body (1) comprises: a first impermeable portion (3) extending longitudinally from the external end (2a) of the port body (1); and a mesh portion (4) extending longitudinally from the subcutaneous end (2b) of the port body (1), which mesh portion (4) extends laterally from an inner mesh surface (4a) to an outer mesh surface (4b) by a thickness T; wherein T has a value Tl proximate to the first impermeable portion (3) and a value T2 proximate to the subcutaneous end (2b), and Tl is less than T2.
2. A transcutaneous port according to claim 1 wherein T is equal to the shortest distance between the inner mesh surface (4a) and the outer mesh surface (4b) measured along the direction of a straight line in a plane perpendicular to a longitudinal axis of the port body and originating at the longitudinal axis.
3. A transcutaneous port according to claim 1 or claim 2 wherein: the port body (1) further comprises an internal impermeable portion (6); the internal impermeable portion (6) is located between the first impermeable portion (3) and the subcutaneous end of the port body (2b) and located at least partly within the mesh portion (4); and at least one channel (5) extends longitudinally through the internal impermeable portion (6).
4. A transcutaneous port according to claim 3 wherein the internal impermeable portion (6) has a cross-section of area A in a plane perpendicular to the longitudinal axis, wherein A has a value Al proximate to the first impermeable portion (3) and a value A2 proximate to the subcutaneous end (2b), and Al is larger than A2.
5. A transcutaneous port according to claim 3 or 4 wherein the internal impermeable portion (6) is frustoconical and the base of the frustocone is located adjacent to the first impermeable portion (3).
6. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises pores with a diameter of 50 to 2000 microns.
7. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises pores of 500 to 1250 pm in diameter.
8. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises a stiff mesh.
9. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises a region of stiff mesh located along all or part of the inner mesh surface (4a) and a region of flexible mesh located along all or part of the outer mesh surface (4b).
10. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises a plurality of ribs arranged in a lattice.
11. A transcutaneous port according to claim 10 wherein the lattice comprises a regular arrangement of unit cells.
12. A transcutaneous port according to claim 10 or 11 wherein the lattice is a diamond hexagonal lattice.
13. A transcutaneous port according to any one of claims 10 to 12 wherein at least 90% of the ribs terminate in (i) a vertex with another rib, or (ii) an impermeable portion (3, 6).
14. A transcutaneous port according to any one of claims 10 to 13 wherein the thickness Tl corresponds to the thickness of a single unit cell and the thickness T2 corresponds to the thickness of five or more unit cells.
15. A transcutaneous port according to any preceding claim wherein the first impermeable portion (3) comprises a smooth surface located adjacent to the outer mesh surface 4b.
16. A transcutaneous port according to any preceding claim wherein the mesh portion (4) comprises a rough surface.
17. A transcutaneous port according to any preceding claim wherein each of the first impermeable portion (3), the mesh portion (4) and where present the internal impermeable portion (6) comprise titanium.
18. A transcutaneous port according to any preceding claim wherein the port body (1) comprises a coating on at least part of its surface.
19. A transcutaneous port according to claim 18 wherein the coating comprises one or more of a biocidal metal, hydroxyapatite, cadherin or fibronectin.
20. A transcutaneous port according to any preceding claim wherein the port body (1) comprises a surface treatment incorporating a biocidal metal on at least part of its surface.
21. A transcutaneous port according to any preceding claim wherein the port body (1) has an approximately circular cross-section in all planes perpendicular to the longitudinal axis.
22. A transcutaneous port according to any preceding claim wherein the port body (1) is integrally formed.
23. A transcutaneous port according to any preceding claim wherein the height of the mesh portion (4) is from 1000 to 5000 microns.
24. A method of manufacturing a transcutaneous port comprising a port body (1), wherein the transcutaneous port is as defined in any one of claims 1 to 23, comprising integrally forming the port body (1).
25. A method according to claim 24, wherein the method comprises 3D printing the port body (1).
26. A method according to claim 24 or 25 wherein the method further comprises providing a coating on at least part of the surface of the port body (1), and wherein the coating comprises one or more of a biocidal metal, hydroxyapatite, cadherin or fibronectin.
27. A method according to claim 24 or 25 wherein the method further comprises applying a surface treatment to at least a part of the surface of the port body (1), said surface treatment comprising incorporating a biocidal metal into the surface.
28. A method of inserting a transcutaneous port comprising a port body (1) into the human or animal body, wherein the transcutaneous port is as defined in any one of claims 1 to 23, the method comprising: making an incision in the skin of the body; placing the mesh portion (4) of the port body (1) in contact with the dermis exposed by the incision; and placing at least a part of the first impermeable portion (3) to stand proud of the epidermis at the incision.
29. A method according to claim 28 wherein the method further comprises attaching the transcutaneous port to the body with temporary attachment means.
GB2017441.3A 2018-02-06 2019-02-05 Transcutaneous port and method for manufacture Active GB2587550B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1801916.6A GB201801916D0 (en) 2018-02-06 2018-02-06 Transcutaneous port and method for manufacture
PCT/GB2019/050304 WO2019155195A1 (en) 2018-02-06 2019-02-05 Transcutaneous port and method for manufacture

Publications (3)

Publication Number Publication Date
GB202017441D0 GB202017441D0 (en) 2020-12-16
GB2587550A true GB2587550A (en) 2021-03-31
GB2587550B GB2587550B (en) 2022-03-30

Family

ID=61730970

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1801916.6A Ceased GB201801916D0 (en) 2018-02-06 2018-02-06 Transcutaneous port and method for manufacture
GB2017441.3A Active GB2587550B (en) 2018-02-06 2019-02-05 Transcutaneous port and method for manufacture

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1801916.6A Ceased GB201801916D0 (en) 2018-02-06 2018-02-06 Transcutaneous port and method for manufacture

Country Status (2)

Country Link
GB (2) GB201801916D0 (en)
WO (1) WO2019155195A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578063A (en) * 1984-09-14 1986-03-25 W. L. Gore & Assoc., Inc. Central venous catheter
EP0343114A1 (en) * 1988-05-20 1989-11-23 Asahi Kogaku Kogyo Kabushiki Kaisha Transcutaneous device
US20070060891A1 (en) * 2003-12-08 2007-03-15 Richard Skiera Implant with a skin penetration section
WO2012007755A2 (en) * 2010-07-13 2012-01-19 Ostomycure As Surgical implant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578063A (en) * 1984-09-14 1986-03-25 W. L. Gore & Assoc., Inc. Central venous catheter
EP0343114A1 (en) * 1988-05-20 1989-11-23 Asahi Kogaku Kogyo Kabushiki Kaisha Transcutaneous device
US20070060891A1 (en) * 2003-12-08 2007-03-15 Richard Skiera Implant with a skin penetration section
WO2012007755A2 (en) * 2010-07-13 2012-01-19 Ostomycure As Surgical implant

Also Published As

Publication number Publication date
GB201801916D0 (en) 2018-03-21
GB202017441D0 (en) 2020-12-16
WO2019155195A1 (en) 2019-08-15
GB2587550B (en) 2022-03-30

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