GB2585246B - Streptomyces clavuligerus - Google Patents

Streptomyces clavuligerus Download PDF

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Publication number
GB2585246B
GB2585246B GB1909698.1A GB201909698A GB2585246B GB 2585246 B GB2585246 B GB 2585246B GB 201909698 A GB201909698 A GB 201909698A GB 2585246 B GB2585246 B GB 2585246B
Authority
GB
United Kingdom
Prior art keywords
streptomyces clavuligerus
clavuligerus
streptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1909698.1A
Other versions
GB201909698D0 (en
GB2585246A (en
Inventor
J Honicker Katherine
Crowhurst Nicola
Gary Kendrew Steven
J Collis Andrew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Intellectual Property No 2 Ltd
Original Assignee
GlaxoSmithKline Intellectual Property No 2 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Intellectual Property No 2 Ltd filed Critical GlaxoSmithKline Intellectual Property No 2 Ltd
Priority to GB1909698.1A priority Critical patent/GB2585246B/en
Publication of GB201909698D0 publication Critical patent/GB201909698D0/en
Priority to PCT/EP2020/068761 priority patent/WO2021004912A1/en
Priority to KR1020227003395A priority patent/KR20220031043A/en
Priority to MX2022000250A priority patent/MX2022000250A/en
Priority to EP20737125.3A priority patent/EP3994154A1/en
Priority to CN202080048999.0A priority patent/CN114072493A/en
Publication of GB2585246A publication Critical patent/GB2585246A/en
Application granted granted Critical
Publication of GB2585246B publication Critical patent/GB2585246B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB1909698.1A 2019-07-05 2019-07-05 Streptomyces clavuligerus Active GB2585246B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB1909698.1A GB2585246B (en) 2019-07-05 2019-07-05 Streptomyces clavuligerus
EP20737125.3A EP3994154A1 (en) 2019-07-05 2020-07-03 Streptomyces clavuligerus
KR1020227003395A KR20220031043A (en) 2019-07-05 2020-07-03 Streptomyces clabuligerus
MX2022000250A MX2022000250A (en) 2019-07-05 2020-07-03 Streptomyces clavuligerus.
PCT/EP2020/068761 WO2021004912A1 (en) 2019-07-05 2020-07-03 Streptomyces clavuligerus
CN202080048999.0A CN114072493A (en) 2019-07-05 2020-07-03 Streptomyces clavuligerus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1909698.1A GB2585246B (en) 2019-07-05 2019-07-05 Streptomyces clavuligerus

Publications (3)

Publication Number Publication Date
GB201909698D0 GB201909698D0 (en) 2019-08-21
GB2585246A GB2585246A (en) 2021-01-06
GB2585246B true GB2585246B (en) 2023-06-21

Family

ID=67623332

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1909698.1A Active GB2585246B (en) 2019-07-05 2019-07-05 Streptomyces clavuligerus

Country Status (1)

Country Link
GB (1) GB2585246B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114181878A (en) * 2021-12-08 2022-03-15 上海交通大学 Method for increasing TG enzyme fermentation level by enhancing transcription level of amino acid synthesis gene

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Journal of Industrial Microbiology and Biotechnology, vol. 46, 2019, Cho et al, "Improved production of clavulanic acid by reverse engineering and overexpression..." pp. 1205-1215 *
Metabolic Engineering, vol. 11, 2009, Xiang et al, "Application of a double-reporter-guided mutant selection method..." pp. 310-318 *
Turkish Journal of Biology, vol. 41, 2017, Kizildogan et al, "Genetic engineering of an industrial strain of Streptomyces clavuligerus..." pp. 342-353 *

Also Published As

Publication number Publication date
GB201909698D0 (en) 2019-08-21
GB2585246A (en) 2021-01-06

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