GB2551892A8 - Cancer treatment - proton tomography apparatus and method of use thereof - Google Patents

Cancer treatment - proton tomography apparatus and method of use thereof Download PDF

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Publication number
GB2551892A8
GB2551892A8 GB1707550.8A GB201707550A GB2551892A8 GB 2551892 A8 GB2551892 A8 GB 2551892A8 GB 201707550 A GB201707550 A GB 201707550A GB 2551892 A8 GB2551892 A8 GB 2551892A8
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United Kingdom
Prior art keywords
signal
particle
positively charged
sheet
imaging
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1707550.8A
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GB2551892B (en
GB201707550D0 (en
GB2551892A (en
Inventor
Davis Lee William
r amato Mark
Ruebel Nick
Reno Jillian
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Protom Int Holding Corp
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Protom Int Holding Corp
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Filing date
Publication date
Priority claimed from US15/167,617 external-priority patent/US9737733B2/en
Priority claimed from US15/348,625 external-priority patent/US9855444B2/en
Priority claimed from US15/402,739 external-priority patent/US10188877B2/en
Priority claimed from US15/467,840 external-priority patent/US20170197099A1/en
Application filed by Protom Int Holding Corp filed Critical Protom Int Holding Corp
Publication of GB201707550D0 publication Critical patent/GB201707550D0/en
Publication of GB2551892A publication Critical patent/GB2551892A/en
Publication of GB2551892A8 publication Critical patent/GB2551892A8/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4064—Arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
    • A61B6/4085—Cone-beams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4007—Arrangements for generating radiation specially adapted for radiation diagnosis characterised by using a plurality of source units
    • A61B6/4014—Arrangements for generating radiation specially adapted for radiation diagnosis characterised by using a plurality of source units arranged in multiple source-detector units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4064—Arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
    • A61B6/4071—Pencil beams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4233—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using matrix detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
    • A61B6/541—Control of apparatus or devices for radiation diagnosis involving acquisition triggered by a physiological signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1054—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using a portal imaging system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065—Beam adjustment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Mathematical Physics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Nuclear Medicine (AREA)

Abstract

An apparatus 900 for determining a position of a tumor 720 in a patient 730 in a treatment room using positively charged particles. Apparatus 900 comprising: a synchrotron sequentially transporting positively charged particles into the patient 730; and an imaging system comprising: first and second sheets 760,770 each comprising a light emitting element; a first detector 812 that generates a first signal in response to imaging first photons emitted when a first positively charged particle passes through the light emitter of first sheet 760; and a second detector 814 forming a second signal on imaging second photons emitted the first positively charged particle passes through the light emitter of second sheet 770; and a controller determining a first segment V1a of a beam path of the first particle using the first signal and the second signal. The imaging system may comprise a third sheet 780 with a light emitting element to yield a third signal due to the first particle; and a scintillation plate 710 of a tomography system to generate a fourth signal due to the first particle where the controller determines segments of the beam path of the first particle using the first, second, third and fourth signals.
GB1707550.8A 2016-05-27 2017-05-11 Cancer treatment - proton tomography apparatus Active GB2551892B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15/167,617 US9737733B2 (en) 2008-05-22 2016-05-27 Charged particle state determination apparatus and method of use thereof
US15/348,625 US9855444B2 (en) 2008-05-22 2016-11-10 X-ray detector for proton transit detection apparatus and method of use thereof
US15/402,739 US10188877B2 (en) 2010-04-16 2017-01-10 Fiducial marker/cancer imaging and treatment apparatus and method of use thereof
US15/467,840 US20170197099A1 (en) 2010-04-16 2017-03-23 Semi-automated cancer therapy apparatus and method of use thereof

Publications (4)

Publication Number Publication Date
GB201707550D0 GB201707550D0 (en) 2017-06-28
GB2551892A GB2551892A (en) 2018-01-03
GB2551892A8 true GB2551892A8 (en) 2018-03-21
GB2551892B GB2551892B (en) 2020-09-30

Family

ID=59201663

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1707550.8A Active GB2551892B (en) 2016-05-27 2017-05-11 Cancer treatment - proton tomography apparatus

Country Status (3)

Country Link
CN (4) CN107432993B (en)
AU (2) AU2017203110B2 (en)
GB (1) GB2551892B (en)

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DE102018008806A1 (en) * 2018-11-09 2020-05-14 Städtisches Klinikum Dessau Procedure for the authenticity-related correction of the spatial position of the central beam of radiation therapy devices and the patient position
CN111821583A (en) * 2019-04-22 2020-10-27 苏州雷泰医疗科技有限公司 Accelerator treatment device and treatment method
CN110292724B (en) * 2019-07-04 2021-03-09 中国科学技术大学 Online verification method, device and system for proton beam outgoing path and range
CN110917511A (en) * 2019-11-20 2020-03-27 广州科莱瑞迪医疗器材股份有限公司 Safety monitoring and management system for radiotherapy patients
CN111388879B (en) * 2020-03-19 2022-06-14 上海联影医疗科技股份有限公司 Radiation dose determination system, radiation dose determination device and storage medium
CN112083467B (en) * 2020-09-28 2022-05-31 中国科学院近代物理研究所 Three-dimensional dose measurement detection system of particle therapy device
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Also Published As

Publication number Publication date
GB2551892B (en) 2020-09-30
AU2017203110B2 (en) 2018-03-08
CN107569780A (en) 2018-01-12
CN107569782B (en) 2020-12-18
CN107432993B (en) 2020-02-28
CN107569780B (en) 2020-03-06
AU2017203109B2 (en) 2018-12-06
CN111134706A (en) 2020-05-12
AU2017203110A1 (en) 2017-12-14
CN107432993A (en) 2017-12-05
GB201707550D0 (en) 2017-06-28
CN107569782A (en) 2018-01-12
AU2017203109A1 (en) 2017-11-30
GB2551892A (en) 2018-01-03

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