GB2542734A - Seizure detection - Google Patents

Seizure detection Download PDF

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Publication number
GB2542734A
GB2542734A GB1701025.7A GB201701025A GB2542734A GB 2542734 A GB2542734 A GB 2542734A GB 201701025 A GB201701025 A GB 201701025A GB 2542734 A GB2542734 A GB 2542734A
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GB
United Kingdom
Prior art keywords
heart rate
present
rate measurements
percentage difference
seizure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1701025.7A
Other versions
GB2542734B (en
GB201701025D0 (en
Inventor
Brotherstone Ruth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOTHIAN HEALTH BOARD
Original Assignee
LOTHIAN HEALTH BOARD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by LOTHIAN HEALTH BOARD filed Critical LOTHIAN HEALTH BOARD
Publication of GB201701025D0 publication Critical patent/GB201701025D0/en
Publication of GB2542734A publication Critical patent/GB2542734A/en
Application granted granted Critical
Publication of GB2542734B publication Critical patent/GB2542734B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/07—Home care
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0531—Measuring skin impedance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1118—Determining activity level
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/7405—Details of notification to user or communication with user or patient ; user input means using sound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/7455—Details of notification to user or communication with user or patient ; user input means characterised by tactile indication, e.g. vibration or electrical stimulation

Abstract

The present invention provides methods, procedures and systems which may find application in the detection of seizures including, for example epileptic seizures. The methods of the present invention comprise the step of determining the percentage difference between heart rate measurements of a subject, wherein a percentage difference between heart rate measurements indicates that a seizure is about to occur or is occurring. The systems of the present invention comprise means for determining the percentage difference between heart rate measurements of a subject, wherein if the heart rates differ, the system reports the occurrence of a seizure. This invention also provides devices comprising a system according to this invention.
GB1701025.7A 2014-06-20 2015-06-18 Seizure detection Active GB2542734B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1411046.4A GB201411046D0 (en) 2014-06-20 2014-06-20 Seizure detection
PCT/GB2015/051783 WO2015193672A1 (en) 2014-06-20 2015-06-18 Seizure detection

Publications (3)

Publication Number Publication Date
GB201701025D0 GB201701025D0 (en) 2017-03-08
GB2542734A true GB2542734A (en) 2017-03-29
GB2542734B GB2542734B (en) 2022-05-11

Family

ID=51409916

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1411046.4A Ceased GB201411046D0 (en) 2014-06-20 2014-06-20 Seizure detection
GB1701025.7A Active GB2542734B (en) 2014-06-20 2015-06-18 Seizure detection

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1411046.4A Ceased GB201411046D0 (en) 2014-06-20 2014-06-20 Seizure detection

Country Status (2)

Country Link
GB (2) GB201411046D0 (en)
WO (1) WO2015193672A1 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142523A1 (en) * 2006-06-07 2007-12-13 Hobo Heeze B.V. Patient monitoring system for the real-time detection of epileptic seizures
WO2010135518A1 (en) * 2009-05-20 2010-11-25 Sotera Wireless, Inc. System that monitors patient motion and vital signs
US20110270096A1 (en) * 2010-04-29 2011-11-03 Ivan Osorio Algorithm for detecting a seizure from cardiac data
WO2011137235A1 (en) * 2010-04-29 2011-11-03 Cyberonics, Inc. Methods for detecting a seizure from cardiac data
WO2011149565A1 (en) * 2010-05-28 2011-12-01 Research Triangle Institute, International Apparatus, system, and method for seizure symptom detection
US20120271181A1 (en) * 2011-04-25 2012-10-25 Cyberonics Inc. Identifying seizures using heart rate decrease
US20120277605A1 (en) * 2011-04-29 2012-11-01 Cyberonics Inc. Dynamic heart rate threshold for neurological event detection
US20120310050A1 (en) * 2010-10-01 2012-12-06 Flint Hills Scientific, L.L.C. Detecting, Assessing and Managing Epilepsy Using a Multi-Variate, Metric-Based Classification Analysis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11272874B2 (en) * 2008-01-25 2022-03-15 Flint Hills Scientific, Llc Contingent cardio-protection for epilepsy patients
US10004446B2 (en) * 2013-03-14 2018-06-26 Flint Hills Scientific, L.L.C. Parametric seizure detection

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142523A1 (en) * 2006-06-07 2007-12-13 Hobo Heeze B.V. Patient monitoring system for the real-time detection of epileptic seizures
WO2010135518A1 (en) * 2009-05-20 2010-11-25 Sotera Wireless, Inc. System that monitors patient motion and vital signs
US20110270096A1 (en) * 2010-04-29 2011-11-03 Ivan Osorio Algorithm for detecting a seizure from cardiac data
WO2011137235A1 (en) * 2010-04-29 2011-11-03 Cyberonics, Inc. Methods for detecting a seizure from cardiac data
WO2011149565A1 (en) * 2010-05-28 2011-12-01 Research Triangle Institute, International Apparatus, system, and method for seizure symptom detection
US20120310050A1 (en) * 2010-10-01 2012-12-06 Flint Hills Scientific, L.L.C. Detecting, Assessing and Managing Epilepsy Using a Multi-Variate, Metric-Based Classification Analysis
US20120271181A1 (en) * 2011-04-25 2012-10-25 Cyberonics Inc. Identifying seizures using heart rate decrease
US20120277605A1 (en) * 2011-04-29 2012-11-01 Cyberonics Inc. Dynamic heart rate threshold for neurological event detection

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Bateman, L.M. et al., "Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors", vol. 131, no. 12, Oct 2008, pages 3239-3245 *
Chua, E. et al., "Improved patient specific seizure detection during pre-surgical evaluation", Clinical Neurophysiology, IE, vol. 122, no. 4, Oct 2007, pages 672-679 *
Tang, Y. et al., "A tunable support vector machine assembly classifier for epileptic seizure detection", Expert Systems with Applications, vol. 39, no. 4, Jan 2012, pages 3925 - 3938 *

Also Published As

Publication number Publication date
GB201411046D0 (en) 2014-08-06
GB2542734B (en) 2022-05-11
WO2015193672A1 (en) 2015-12-23
GB201701025D0 (en) 2017-03-08

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