GB2536072A - Method for determination of the choice of the active ingredients of biological and chemical composition against infectious, oncology, skin diseases, which are - Google Patents

Abstract

A composition in the form of a soap, scrub, cream, paste or tincture for cleansing the skin. The composition is intended for prevention or treatment of skin diseases and disorders, including skin cancer. It is also used to protect the skin against bacterial and viral infections, radiation injuries, and premature aging. It may include antitumour substances such as alkaloids, proteins, acids, oils and terpenes. It may contain antiprotozoal drugs such as nystatin or metronidazole. The composition comprising: 80-90% salts of fatty acids from vegetable and animal fats; 10-15% unrefined oils which may be olive oil, palm oil, sunflower oil, peach oil, coriander oil, flax oil, or fir oil; 10-15% thickeners which may be sorbitol, glycerine, albihtol, chalk, paraffin or vegetable flour; herbal material, essential oils, flavouring, alcohol, antibiotic and antiprotozoal drugs, and water. Also described is a method of selecting the substances to be used.

Description

Method for determination of the choice of the active ingredients of biological and chemical composition against infections, oncology, skin diseases, which are preventing carcinogenesis and varios of viruses and cosmetics recipes.

Field of invention

10001]This invention relates to therapeutic compositions and is intended for the treatment of the skin diseases, cancer, viruses and determination of the active substances against them, as well as can be used in cosmetology, hygiene, oncology.

Background of the invention

[0002]Over the past 50 years the new-generation medications have appeared, which are preventing the progression of dermatological and oncological diseases and virus infections. Various previously used skin disinfectants are known now -RU2345782, RU2010129444, EE00781U1 and other literature, such as "Cosmetics and Season of the Year" -S. N. Lensina, 1996. The disadvantage of the above mentioned inventions is the fact that they included a small quantity of vegetable substances with antiproliferative properties and their frequent use caused allergic disorders, as well as the use of the mentioned minerals and the uncertainty of many types of ethiology of cancer and some viruses leads to an increase of pathogenic flora and does not have the desired effect.

[0003]The essence of the invention and the problem is to identify the vegetable and chemical antiproliferative properties and to determine the method for identification of these substances in order to protect the skin from the penetration of pollutants, viruses, microbial flora, to block cancer and viral RNA, which are causing cancer and skin diseases and are present in the soaps, ointments, pastes, peeling etc. The main components are the antineoplastic herbals, their substances (proteins 10-30%, amino acids, essential oils 2-10% alkaloids salts 2-3%, terpenes), which damage the bacterias, viruses, turners by means of their antibacterial properties by mixing with their toxins, and block the transmission of viral and bacterial infection (RNA) and the further expansion of metastasis.

[0004]The technical result -by means of this product, its new thermal activation methods, new manufacturing technologies, new supplements, ferments and biogants (alkaloids, proteins, terpenes, acids, essential oils) and their chemical analogues, the antitumor effect, as well as the reduction in the toxicity and increase in antitumor indicators can be achieved.

10005]The objective of the invention is a method for determination and identification of vegetable substances, which correspond to the above mentioned function (antiproliferative), and, in particular, the fruits of cardamom, seeds of coriander, cloves, lovage, vanilla, cumin, nasturtium, bird cherry, geerah, black pepper, flowers of lilac, roots of horseradish, ginger, garlic, laurel leaves, celandine, birch bark, cinnamon and their chemical analogues, antiprotozoal, antiseptic preparations. Neurotic and psychogenic conditions, constant poisoning with chemical and biological toxins, unhealthy diet, food poisoning, etc., lead to toxication of the body.

Reticular and endocrine system cannot cope with the load of toxic substances (nitro, benzolo-, sulfur and other compounds), by connecting with radiative-bacterial flora poisons the blood; the body releases toxins into the skin epithelium and forms tumors, especially while producing enzymes (serotin), catecholarnine, hormones, lipids during the childhood, climatic, premenstrual, prenatal periods.

The protein-fatty imbalance and blocking of the lymphatic and alveolar systems are occurring. Significant damage to the skin, leading to skin cancer, are caused by chemical and nuclear accidents at power herbals, as well as the factors listed in patent No. N020120192 and other studies contain a large amount of bacteria and sponges, which are causing cancer and sarcoma under certain conditions.

Along with such microbes as sponges, cellulose-fermenting bacteria, cause various kinds of alveolar cell carcinomas. That is why it is especially important to clean the skin in the morning and evening to use the cosmetics offered in this series daily. The bactericidal properties of the skin are the higher, the cleaner they are.

The present invention can be used every day and some of them, which do not contain antibiotics or antiprotozoal drugs, several times per day. Different oils and acids can be used in order to prevent skin dryness.

[0006]One composition of the present invention includes soap, scrub, cream, ointment, paste with antiproliferative substances of the herbals.

Another therapeutic composition of the present invention includes lactic and bioactive additions, herbal extracts that remove neuro-psychological irritation and pathogenic flora.

One more version of the invention involves the method of determination of the active substances and their selection against pathogenic (oncologic, infectious) flora, according to similarity and structure of the chemical formula of infectious flora with the antiproliferative substances of vegetable and chemical origin.

Transcription of figures Figure No.1 --class of phisopoda type Sarcomastigophora, gen anaboena *Arcel la* and polips typ Obelia.

Figure No. 2 -Structure of ring cell carcinoma from tipe polips in the material.

Figure No. 3 -Round-cell carcinoma microscopy.

Figure No. 4 -Hepatitis and Huh-7 biochemical structures.

Figure No. 5 -MCF-7 biochemical structure.

Figure No.6-Testacean cancer originating from relative Cerhalapsis, Trilobites.

Figure No. 7 -Metronidazole biochemical structure.

Revelation of the invention [0007]The present invention /composition/ -soap, cream, scrub, cream for face and body are effectively exfoliating the comified skin cells. Protects skin from pathogenic flora, accumulated toxins, secretion of sweat and sebaceous glands, dust, soot, disorders of skin physiology, as well as ensure the skin elasticity and firmness. The spread of metastasis and viruses block in patented material the smells of essential oils, oils, terpenes, alkaloids, which are similar in chemical structural formula to these infections.

[0008]The essence of the method for the determination and selection of the active substances against the appropriate cancer cells, viruses and other infections is just that. However, there are alkaloids and essential oils, acids of listed herbals and chemicals, which are similar in chemical structural formula to the selected infections -cancer cells or the same types of cancer, viruses -and they block the RNA transmission of this infection to the healthy cell.

In the first part of the method the definition of morphological and biochemical/chemical tumor structure and its infections (viruses and bacteria) is provided in comparison to the medicinal substances and products (chemical structure of the formulas of medicinal substances, oils, alkaloids). For example the structure of ring cell carcinoma, originating from the class of phi sopoda type Sarcomastigophora, gen anaboena *Arcella* and from polyps and Huh-7, has a structure of hexagonal tetrahedron with a circular DNA inside.

The same as some sarcomas originating from the same type of amoebas, have the similar chemical formula and structure of the tumor, are similar to the structure of the muscarine tetrahedron and some alkaloids (piperine, morphine) and oils (linalool, camphor).

Metronidazole, by morphological (chemical structure of the formula) structure, are extracted from amantia,family Streptomyces,domain eulcariota,are similar to the structure of this tumor. Has the following chemical formula: ( muscarine) 01-1 (piperine) CH3 H3C CH3 Chemical structure of the muscarine tetrahedron, from which metronidazole has been derived, as well as the chemical structure of alkaloid piperine is similar and can be compared in this method with the chemical formula of some viruses (hepatitis, herpes), which causes human hepatocarcinoma (Huh-7.),(figure N94).

round-cell cancer and some viruses (smallpox, influenza) and therefore the chemical formula can be applied in the first part of this method for the treatment of these infections (see examples No. 2, 4, 5, 8. 9, 12, 14).

In the second part of the method the definition of palaeontological and morphological tumor structure and Es infections (viruses and bacteria) is provided in comparison to the medicinal substances and products (the structure and color of the seeds, stems, flowers). For example the structure of ring cell carcinoma, originating from the class of phisopoda type Sarcomastigophora, gem anaboena * Arcella *, from polyptyp Obelia are round structure (Figur No. 1), as well as MCF-7, Huh-7, embryos, cancers, viruses -HIV, influenza, smallpox, etc. Therefore, the plants and round shape substances (seeds of cabbage, coriander, black pepper, Metronidazole -(Figure No.7), (example No.2, 3, 4, 5) are selected.For cancers and viruses of oval shape(MCF-7,squamous carcinoma) -oval seeds and substances,for examples gourd, ginger and oil families (example No. 1, 7, 8, 9). For example, piperine alkaloids are similar in structural formula to the diamond-shaped and round viruses, such as herpes, black smallpox and flue, HIV, and block the transmission of the infection to the healthy cell.(see example No. 2, 9).

In the third section of the method the selection of medicinal substances against oncogene and viruses according to similarity of the acid and amino acid composition of the tumor is determined; it requires the exact chemical composition of a certain type of cancer. Moreover, the simplest types, such as amoeba species relate to eukaryotes, as well as fauna, human and plant life. Therefore, it is possible to explain the genetic, biochemical disposition to oncological diseases, which is related to the amino acid composition of DNA and RNA tumors originating from the simplest species and bacteria, animal species and human. Taking into account the similarity of amino acids in both types of DNA or RNA, the infection and the occurrence of the tumor takes place, make the metastasics,more specifically microorganisms, cancer bacteria in animal and human body, in combination with other factors.

In this plant substances is related the seeds of black pepper, petunia, mustard, cloves, flowers of lilac, and which by means of acids (oleanic, citric, nicotinic, salicylic, aspartic, hydrocyanic acids, vitamin C, etc.), essential oils -limonene, linalool, lysozyme -ferment the tumor (Ca, K, sorbitol, chalk for esspeciality etiology small lung cancer), block oncogene RNA and metastasis. (See examples No. 1, 2, 4, 5, 6, 7,9, 11,14).

The etiology of the certain type of cancer is involved in the determination, such as in the example No. 4,5. The mixture of metronidazole was initially tested for B6-F10, but it works better for other types of cancers, such as Huh-7, as its chemical structure is similar to the structure of the muscarine and piperine tetrahedrons. The exact composition and the etiology of the certain type of cancer should be known in order to select acids and amino acids. For example, MCF-7 arises from luminescent sulphur-phosphorus bacteria and treatment should involve the substances that neutralize them -antiallergenic substances -(chloropyramini, hydrochloridum), (aspirin, cocoa, caffeine, mug, cloves), cardiac glycosides, glucose, terpenes, oils -petroleum jelly, castor, linseed, sea buckthorn, etc. -for vascular distention, detoxication sush as -S, CO2, NH2, blood circulation improvement (alkaloid piperine, capsaicin, eugenol, camphora), acids, amino acids (oleic acid, formic acid, lactic acid, vitamins C, A, D, K) (sec examples, especially No.1,2,5,7,9).As well as antipyretic antiallergenic substances -burdock, chamomile, raspberry, cranberry; relaxing -rhubarb, wild ash, castor oil. Likewise, other substances for these diseases are selected.

In the fourth section of the method, the selection of the medicinal substances occurs in accordance with the palaeontological and chemical properties of these types of cancer in order to select the chemical and plant substances in the medicinal products. The structure of the tumor and its infections (viruses and bacteria) is similar in biochemical structure to the plant family from the category of eukaryotes, which involve also human and fauna. For example, domainEukariota, kingdom Plantae, Archaeplastida,gen Sesu lato. For example the structure of ring cell carcinoma, originating from the class of phisopoda type Sarcomastigophora, gen anaboena *Arcella*(figuraIst21) and from polyps is made from eukariotta.And some sarcomas originating from the same type of amoebas, is made to from eukariotta.They are similar by the chemical formula and structure of the tumor descends from carbon and includes -Al2(SO4)3, Carbon dioxide-CaCO3(s) + 2 HC1(aq) CaC12(aq) + CO2(g) + H20(1),CO2,NH2,N,Ca,Mn,Mg,aragonit-(FigurN21), in the human body is developing from the certain epithelium (Figure No. 2).Metronidazole, by of palaeontological, morphological structure, are extracted from amantia,family Streptomyces,domain eukariota,chemical formula is: ( muscarine) cH3 e H3C / H3C (piperine)

OH

Chemical structure of the muscarine tetrahedron, from which metronidazole, has been derived, as well as the chemical structure of alkaloid piperine is similar, with the chemical formula of some viruses (hepatitis, herpes), which causes human hepatocarcinoma (Huh-7.), round-cell cancer and some viruses (smallpox, influenza) and therefore the chemical formula can be applied in the 4 part of this method and for the treatment of these infections (see examples No. 2, 4, 5, 8. 9, 12, 14).

This part of etiology provides that the treatment and prevention of oncological diseases and their metastasis shall involve the substances produced by the plant world of eulcaryotes (examples No. 1,2,3,4,5).

For example, the structure of cell round cancer originating from the class of amoebae, type Sarcomastigophora, has the following chemical composition Al2 (SO4) 3, Carbon dioxide-CaCO3 (s) + 2 HC1 (aq) CaC12 (aq) + CO2 (g) + H20 (1), Me.0O2NH2.CaMg. aragonit (Figure No. 1). Therefore, Me dioxide as well as other dioxides and elements contained in the tumor, should not be used in the medicinal products of this series (examples No. 1,7,9).

The etiology of the certain type of cancer should be known, such as in the example No. 4,5. the mixture of metronidazole was initially tested for B6-F10, but it works better for other types of cancers, as they descended from microorganisms from the Carboniferous,Carbon and Jurassic periods.(FigN26,7).

For example, in case of hypodermal tumor,testacean cancer originating from the typ Arthropoda,klass Crustacea,Isopoda and typ Annelida.gen Cypris sp.Phrnima sp.Gammarus sp,Calanus sp.,typ Amoebozoa, Rhizaria--Plagioppds, Trinema, Cyclopyxis,athers, is was originating from relative typ Cerhalapsis, Trilobites (Encrinurus, Ampyx)--(FigN26).They are species relate to eukaryotes, as well as fauna, human and plant life.The acids and amino should have the exact composition and the etiology of this type of cancer should be known. Likewise, other substances for these diseases are selected.

[0009]In this case, the following substances are listed in the patented material (seeds): clove (Syzygium aromaticum) -eugenol essential oil 2-4%; coriander (Coriandnun sativum) -linalool essential oil 1,5%, pectin, insulin; nasturtium (Tropaelum pentop-hyllum) -geraniol essential oil 1-6%; flowers of gilliflower -eugenol essential oil -2-4%; seeds of geerah (Cuminum Cyminum) -citral essential oil,Curninaldehyde,arom oil,b-pinen,p-cino1,2-etwd3-metil-pirazine,sulfranal, 2-metoksi-3-methilpirasine; seeds of black pepper (Piper nigrum) -cineol essential oil -2-4%; alcaloids -piperine 1-10%; lilac (Siringa vulgaris) -fenogjikozid syringin; cinnamon (Cinnamon) -benzoate, sugar, essential oils-aldehyde,cinnamaldehyde,oxigeneugenoLlinalool,b-cariophyllene, methylchavicol; mustard -glycoside syringin, mustard oil; vanilla (Vanilia Planifolia) -sugar, bitterness, oil; cherry kernels camphor, acids, proteins, flowers of peony (Paeonia officinalis), Paeonia anomala) -arginine, glutamine, Cr, Al, Ca, K, Fe, Mg, S. salicin, carbohydrates, fruits of bird cherry (Radus racemosa) glycoside-prunasin, isoamylmin, trimethylamine, amygdalin, hydrocyanic acid; in alder (Alnus glutinosa) -triterpenoids, phenol up to 4%, gallus acid 6%, chlorogenic acid about 2%, caffeine, PP vitamin; in caraway (Carum carvi) -carvone 65% essential oil -limonene 23% kemferon, quercetin; lovage -(Levistricum officinalis) glycosides, essential oils -terpenes, cineole, corvalol; in laurel (Cinamonum camphora) -camphor, sesquiterpenes, tannin, cinnamaldehyde, essential oil up to 95%; in Schisandra chinensis -organic acids 9-20%, minerals -Mg, Zn, Cu, Ni, Hb, P, S, Kr, Ag, sugar 2%; cardamom -(Eletaria cardamonum) -essential oil -gingerol 23%, cineole, linalyl acetate 9%, myrcene 6,6%, terpinolene 6% and benzoquinone; ginger -(Zingibereciae) phenols, essential oil centibrine.vinegar on the anaerobick fermentation PH4.6,1actic acid,; alkaloids -piperine 10%, (Crasus juss) -pectin, inositol, essential oil, pentosan 6%; horseradish (Arrnoracia rusticana) -essential oil -allylic, mustard, myrosin, menthol; garlic (Allium sativum) -essential oil diaryl disulfides, alliin, allicin, the smell of sulfur, phytosterols, B, C, D vitamins, iodine, pentosan, fiber; celandine -(Chelidonium majus) -alkaloid chelidonine, similar in structure to morphine, gemohelidonin, sanguinarine-anesthetic, protopin, asparagus eugenol, proteins, acids; bark of birch (Betula alba.Bet / pendula) -tarry alkaloid betulin that kills fungi and symbiote of cancer bacterias with fungi, essential oils up to 5% -bicyclic sesquiterpenes, betulinic acid, resin, tarChrysanthemum leaves camphora5%/ As well as antiprotozoal, antiseptic preparations (metronidazole, nystatin).

Specific antitumour substances of the herbals (alkaloids, proteins, acids, oils, terpenes) affect the virus RNA, DNA, and then affect the tumoral genes and produce protective antibodies. Protect the skin from premature aging, infection, radiation injuries by increasing immunity.

Along with the antibiotics (such as metronidazole and nystatin) removes unduly accumulated chitin, cellulose, fungal flora, protozoa (Porifera), which cause various alveolar cell carcinomas.

[00101* These recipes, which consist of the following components -extract of chili, black pepper (their alkaloids -piperine and capsaicine) for dry skin, along with the extracts of cocoa, coconut, parsley, lovage, geerah, linen, pearl barley and antiprotozoal drugs, as well as F, C, D, A vitamins -prevent shedding, nourishes and balances the skin, strengthens the immune system. They can be also used against some viruses.

*Biological components better tone up and strengthen the skin epithelia, especially of fatty origin. Acid skin barrier in combination with fennel, coriander, cloves, black pepper, coconut, cocoa, burdock, linen, pearl barley form a filter against radiation rays. Zinc, vegetable substance in alkaloids and oils, such as eugenol, camphor, brome, reduce the production of sebum, inhibits Sa-reductase, reduce the production of sulphur, heal inflammations. *Eugenol and menthol in the selected herbals and gilliflower, clove oil, cardamom, mint, geerah -calm, slows down the growth of cancer cells, but does not kill them, and can be applied during the skin treatment from radiation, as well as the anesthetic in solutions and pastes.

*Asparaginase in clove buds, gilliflower, cardamom, asparagus, alkaloidpiperine, capsaicin in pepper is struggling with tumour growth by limiting the synthesis of ammonia, L-asparagine, cancer metastasis, melanoma, which are presented on the schedule.S chedule with a model of hepatocarcinoma Huh-7 Additives of glycerin, polyethylene, tetrasodiurn EDTA, acids of citrus, Solanaceae, Umbelliferae, Compositae herbals, blue clay -remove allergic effect, protect the skin from excessive drying, fatigue, irritation, mainly for oily skin, whiten and remove shine.

[0011]Manufactured by soap means of classic hot technique. The inventor also offers to manufacture the product by the following hot techniques.

The first method involves preparation by hot technique for 15-20 minutes, and means soap preparation from Na, K salts of fatty acids, vegetable and animal fats and salmons, which compose 70-85% of the soap weight. After that, during boiling, 10-30% of vegetable oils and their acids (olive, palm, sunflower, peach, coriander, flax) are being added, which were previously whipped for 25-120 seconds.

Third added to the mass (oils, thickeners) in the tank at 80-100 * C min by adding water All the soap mixture when cooking stir every minute for 25 seconds.Thickeners (sorbitol, glycerin, albichtholum, chalk, paraffin), compose 10-15% of the total weight of the product. Water composes 50-200% of the solid soap composition. In this case, vegetable ingredients with no added colorants, dried herbs, seeds, except for inorganic compounds, antibiotics are passing through temperature exposure by dry steam of 60°C for 5-10 seconds and arc being crushed into powder.

b.7 (human beroto tllPro1Ua-alIouafS*ttie* erbid 0.0 toted cdb tcttLI 10% 7.0 83.011117 2 ea 2 at 2 at 3 cd 3 eV 10% 5% 1% 10% 5% 79.7 93.2 76.2 113 17.9 25,7 5-pp (63 18/071) 41.5 In the process of preparation from the herbal extracts, lOg of blend is mixed with 50 ml of phosphate buffer and incubated at 50°C for 30 minutes and 37°C for 18 hours, centrifuged for 5 minutes, and filtered with essential oils, flavouring, alcohol, paint, and compose 2-7% of the total weight, and added at the end of the technology.

At the end of the technology the mass is being whipped for 25 seconds. Poured into molds and solidified at -5 + 10°C for about 72 hours.

The second method involves the preparation of soap from unrefined vegetable oils (olive oil, palm oil, sunflower oil, peach, coriander, linen, fir), added into the vessel first and compose 70-800% of the solid soap composition. Other ingredients and technology are described in the technique No.1.

The soap composition in both recipes is being divided into the following percentage equivalent: a) 70-80% -Na, K, salts of fatty acids of vegetable and animal fats and salmons, as well as vegetable oils (for technique No.1,2).

b) 10-15% -unrefined vegetable oils: olive oil, palm oil, sunflower oil, peach, coriander, linen, fir.

c) 10-15% -thickeners (sorbitol, glycerin, albichtholum, chalk, paraffin, vegetable flour) g) 2-7% -herbal material (seeds), their chemical equivalent, essential oils, flavouring, alcohol, paint.

d) 0,001-0,10% percentage of dry extracts or herbals, antibiotic and antiprotozoal preparations e) 50-200% -water of the solid soup mass g) 0,1-100% -the whole part [0012}Extraction of herbal mixture is being performed in two ways, the first technique involves crashing of the herbal mixture into powder, while being pre-disinfected by steam as described above; in accordance with the second technique, the extraction is being performed at 50°C for 30 minutes and at 37°C for 18 hours in a thermos. The second technique involves the preparation and activation of the herbal enzymes at 65°C ford 30 minutes and at 37°C for 18 hours.

The ready product is stored in a dark room at -10 to +15°C, valid through 24 months, before the expiration date of herbal and antibacterial chemicals. Soap is poured into oval molds by 75, 100, 200 grams, 3-5 cm in radius. On the package the product name, the composition of the main herbal extracts, method of application, content, validity, method of use and destination of the product are presented. Description of the soap is written in English, French, Russian, Chinese, Spanish languages on the packages.

Examples

In the following compositions grams and certain proportions of ingredients are presented, which can be changed by the manufacturer and the exact masses should not be considered as limitations. Used liquids are water-based and the relative weight of each volume of the liquid and the solid ingredient should be considered equal to the mass of water -(1 g/m1) [0013]Example No.1 Soap Soap and herbal mixtureare intended for the treatment of seborrhea, fungal skin diseases, prevention of dermoid,suqamous cancer and coccic form skin cancers.

Mixtura of melilot, cinnamon, dill, chili pepper, smell of essential their oils -1-2%. According to the 1st and 3rd parts of the method, essential oils, which are containing CIOH120, block primarily the transfer of RNA virus to a healthy cell Substances in the herbals, selected by their structural formula and form of seeds, affect and block RNA of infections, oncogene and viruses, which are similar in structure. For example cinnamon produces such substances as lignin, acrolein, phenyl, oxihen in accordance with the 2" and 3"I parts of the method are connecting with L-amino acid, thus blocking oncogenes and viruses, their toxins speciality DNA viruses, as it contains also a-Amyl, a-hexylcinnamaldehyde. Especially of coccal type infections,especiality for "A" nad "B" type blood groups. Taking into account that tetrahedron of the hepatitis B, C, Huh-7 contains DNA, similar to 80 structure, other substances,they are combine with hemoglobin and better develop their antibacterial properties as well as protect from hemolytic anemia and jaundice.

Piperine relaxes muscles and kills, splits toxins in combination with some acids (for example sulphur compounds in case of MCF-7).

(cinamaldehyde) (oxygen) ACk;r8 A I-1 00 "i I16.6' Manufactured by the technique No.1.Composition of the recipe: water -200300%; melting at 75-100°C -Potassium salts of fatty acids of animal fats, salmons -70-85%; glycerol cocobetain, palm oil, coconut oil, Tetrasodium Etidronate, Tetrasodium EDTA -10-15%, 2.7% pink paint, alcohol and fruit infusions of the extracts, prepared on the basis of the phosphate buffer at 65°C, melilot, cinnamon, dill, chili pepper, smell of essential their oils -1-2%.

[0014]Example No.2 Scrub -cream The mixture consists of moisture of round herbals (ginger root, yellow or white chrysanthemum flowers, flowers of white melilot, bark of birch, yellow mustard, coriander seeds and leaves, white pepper seeds, barley,liine flour and oil) -1%10% extraction on the basis of the phosphate buffer at the enzyme activation at 65°C. According to the chemical formula, oils and alkaloids of these herbals are ander of infections, round viruses (influenza, pox, HIV) and blocked their RNA and metastases of cancer cells, such as colloid kidney carcinoma, round cell carcinoma, small-cell lung carcinoma, medullary carcinoma, Huh-7.Pearl barley creates a protective film from viruses. Used for oily skin. Scrub is being diluted before use of distilled water, which composes 100-300% of the dry composition.

The composition of the recipe: Glycerin, Isopropyl Stearate, Ceteareth-20, Propylparaben, Methilparaben, Ethilparaben, Laureth sulfat, Na, Isopropil myristate, Poliurethane, Poliethilen, Diethilenglikool, Sodium chlorid, Triethalomin -70-80%; Pearl powder, Carbomer, Tocopheril acetate, Buthilparaben, Tetasodium EDTA -15-20%; herbal extracts, scents of coriander and pepper - ingradients mixed, packed on the boxes 150-300mg.

[0015]Example No.3 Cream Manufactured by hot technique, ie all ingredients are being boiled at 80°C for 2-6 minutes, then the extracted mixture by the Technique No. 2 at 65°C of the enzyme activation.

The composition of the recipe: distilled water -50-200%; Glicerin, Ceteareth-20, Dibutil Adibat, Heksil; Aurat, Tocopheril, Methilparaben, Propilparaben, Buthilparaben -75-80%; Koriander oil, Liina oil, Camphora, Alcohol, Oksildodekanol -10-15%; white pepper powder and clover seeds, extracts (1% and 10% in strength), yellow mustard, white lithe, white pepper seeds, yellow chrysanthemum flowers, bark of birch, ginger roots, flavouring, fragrance of white pepper.

Plant mixture is applicable against Huh-7. [0016]Example No. 4 Soap-cream Product and herbal mixture are intended for the treatment of skin diseases, as well as used as the protection against viral infection (herpes... etc.) and cancers such as invasive, squamous, which consist of some sexually-transmitted infections.

The mixture of linen, coconut, cacao, metronidazole. Manufactured by the Technique No.1.

The composition of the recipe: water -200-300%; melting at 100°C in water bath for 10 minutes -sodium salts of fatty acids of animal fats (Na.-Sodium Tallowatte) -70-80% of the total soap composition. To add additional soap basis -10-15% of coconut slices, glycerol, linseed oil, tetrasodium etidronate, tetrasodium EDTA.

To turn off heat, to add 2-7 % of orange paint, alcohol, cocoa and 1-2% of essential oil, linen, cocoa. At the end of the soap production 50 mg of the antibiotic metranidazol are added per 1 kg of ready soap and the mixture should be mixed up.

Soap is poured into a long oval molds, hardens for 78 hours, knocked out of the molds and cut into 75, 100, 200 grams. The name is stamped.

[0017]Example No. 5. Scrub Product and herbal mixture are intended for the treatment of skin diseases, as well as used as the protection against viral infection (herpes... etc.) and cancers such as invasive, infiltrative, squamous, which consist of some sexually-transmitted infections. The mixture of linen, coconut, cocoa, metronidazole. The mixture consists of a dry powder, hermetically packed in tubes by 100, 200grams and should be diluted by the buyer 2-3 times before use, by 200-300m1 of boiled water respectively.The scrub ingredients are mixed with vegetable flour and undergo temperature exposure at 60°C for 2-3 minutes and consist of -Gliceryn, Cocamidopropilbetoin, Polietilen, Carbomer, Polyurethan, Triethalomin, Tocopheryl acetete, Phenoxiethanol, Citronelol, Methilparaben, Propilparaben, Ethilparaben, dry linseed oil -75-80%. And as an additional basis -10-15% of coconut slices, glycerol, tetrasodium EDTA, 100 milligrams of metronidazole per 1 kg of the product; essential oil scent, linen, cocoa -1-2%.

[0018] Example No. 6. Soap.

This soap and vegetable mixture is used against viruses (hepatitis), for the prevention of skin cancers, other MCF-7,(page N210.22) and acts as an anesthetic. Mixture of seeds of coriander, clove, cardamom and zinc can be used for anesthesia. The technology is the following -potassium salts of fatty acids of animal fats are melting at 70-80%; coriander oil, coconut, as well as sodium chloride, glycerin, triethalomin, PEG-9, cellulose, tetrasodium EDTA, tetrasodium etidronate -10-15%; fruit infusions of the seeds of coriander, cardamom, cloves, prepared at 50°C, Zn, brown paint, essential oil scent, seed of cloves and cardamom -5-10%; water -50-200%.

[0019]Example No. 7. Soap-scrub Soap-cream and vegetable mixture is applicable for dry, oily skin, against skin diseases, radiation, viruses. Mixture of seeds of Cinamonum camphora, nasturtium, vanilla, cardamon, burdock,limone sceen,eactus, walnuts,barley flour, chive, milk powder (1% and 10% in strength) and used against B-6F-10, MCF-7. The aroma oil of dill is costed cuminaldehide which the bloced DNA,RNA viruses (herpes simpels), for the method 1 and 111. Plant mixture is applicable to other therapeutic and pharmaceutical compositions.

laabilityr4 Ortrd (FIEE) Ex Ex land leEf Lard led artperertscarpreds (1°4 (5°4 (r4 (99 E MSilfty 1 mixture 1 mixture 2 mixture 2 mixture hi the second laurel lea mixture the content of cinnamaldehyde and camphor reduces proliferation of human breast cancer. Manufactured by hot Technique No.1. Composition of the recipe: to melt potassium salts of fatty acids of animal fats (K.-Sodium Tallowatte) -70-80% of the total composition at 70-100°C. To add additional soap basis, consisting of coriander oil, olives, sodium lactate, sodium chloride, disodium phosphate, lauryl sulfate, pentasodium pentat, petasodium phosphate, tetrasodium etidronate, tetrasodium EDTA -10-15%. Then the milk powder, listed fruit fusions of vegetable mixture and their essential oils are added. The mixture is divided into two portions; into one portion the red dye is added, the mold should be half filled, sprayed with alcohol for a good reaction with the different mass and filled with the remaining 50% of the mass with black dye. The name knocked is stamped after setting solid (after 72 hours). Distilled or purified water composes 50-100% of the solid soap.

[0020] Example No. 8.Cream of peat mud.

The product is intended for the prevention of virus infection, such as retro, adeno, heart cancer, skin cancer, MCF-7. immunity improvement of healthy cells. Tested on MCF-7. The mixture of extracts is composed of peat acid -albichtholum, oat flour, Yalopeno pepper fruits, gilliflower, coriander, dill of 1% 14 10% in strength.

Alkaloids and essential oils, peat acids -albichtholum and listed herbals, which are similar in chemical structural formula with cocco -rhombencephalic viruses, block RNA virus transmission to the healthy cell.Peat mud recipe consists of: 5085% dried peat mud; 15-20% glycerol; 15-20% chalk, black or white clay, talc; 10% Methylparaben, Isopropyl rnyristate, Propilparaben; 5-10% fruit infusions from alcohol extracts or phosphate buffer; 100-400% water. Preparation method: peat mud melted in a water bath at 80 °C with water, clay and chemicals; the quantity of water should be 2-3 times more than the dry weight of the product. Extracts: essential oil, jalopeno, coriander gillyflowers should added 5 minutes before the end of the boiling. Mix should be mixed every 1-2 minutes, then whipped for 1-2 minutes,cooled to 50°C and poured into tubes by 150-300 mill.. [0021]Example No. 9. Soap-cream The product is used as in the previous recipe. The mixture consists of moistures of herbals solution of 10% in strength:chrysanthemum, seeds of geerah(Cuminum Cyminum),Carurn carvi, Levistricurn officinalis, nasturtium, parsley,Amonii caustricum and green brilliant of 0,1-10% in strength. Manufacturing is the following. The aroma oil of geerah, parsley, caraway, *Apiaceae -contains terpenoid (carvone) (5) if is costed cinnamaldehide which the bloced DNA,RNAsome viruses (herpes simpels) These plants block the transfer of the virus in accordance with the 2" part of the method, taking into account the similar stem structure and specific stem structure of the virus. They are also applied for measles virus, anthrax, FMD, similar to similar seeds in comparison with the structure of the infection.

According to the 1st and 3rd parts of the method, essential oils, which are containing Cl OH120,block primarily the transfer of RNA virus to a healthy cell. Potassium salts of fatty acids of animal fats (K.-Sodium Tallowatte) -70-80% -should be melted at 70°C. To add additional soap base, consisting of flaxseed oil, palm oil -(sodium palmat) coconut powder (sodium-cocoate), sodium chloride, talc, wax (paraffin-), sodium sulfate, metilpropional, peg-9, tetrasodium EDTA, tetrasodium etidronate -10-15%; white and red titanium dioxide, parsley and chrysanthemums leaves, parsley essential oil -2-7%; brilliant green -0,1-1%. Water for product dilution -50-200%. Soap should be boiled for 15 minutes, then the herbal powder, colour, flavouring are added, poured into round molds by 75, 100, 200 g, only 30-40% of solution at first, with green dye, then the synthetic bast wisp is added and poured with the remaining mixture 60-70% with black dye. It takes 72 hours to set it solid and then the name is stamped. [0022]Example No. 10. Soap-scrub These herbal substances are used against cancer toxins, as well as can be used against embryonic and bronchial cancerHuh-7. Solution 1 and 10% in strength of essential oils -bird cherry, jasmine, lilac, castor oil and aloe oil, bird cherry fruits, lilac flowers, cherry pits, red pepper, aloe leaves.

Manufactured by the Technique No. I. Melted potassium salts of fatty acids of animal fats -70%, flax oil, sodium salicylate, sodium chloride, sorbitol, unrefined cow milk, tetrasodium EDTA, tetrasodium etidronate castor, lilac and aloe oil -15-30%, extracts are prepared on the basis of the phosphate buffer at activation of extract enzymes at 50°C for 30 minutes and at 37°C for 18 hours.

Perfume -essential oil of lilac, jasmine, bird cherry, lilac-blue colour -2-5%; alcohol for soap fixturing between the masses and spotting of moulds. Soap is poured into square moulds of 7 and 10 sm, 75, 100, 200 grams in weight.

First, as in the previous recipe, 20% of the product is poured in the mould, the bast wisp, which is 1-2 cm less than the mould, is put in the mould and then the rest mass of the soap is poured.

Soap is hardening at -5 + 1°C for 48 hours and at + 5°C for more 52 hours. The name is stamped on the soap after 48 hours after hardening.

[0023]Example No. 11. Soap -cream..

The use of herbal extracts in the soap from the skin cancers and such viruses as herpes and hepatitis, Huh-7. The mixture consists of infusions of herbals of celandine, flax, mustard, lime juice, coconut powder and birch bark, flax and pumpkin oil 50/50%.,Ca, pumpkin seed oil, Indian tea. Produced by the hot Technique No.2. To melt flax and mustard oils at 100°C in equal proportions 50/50 -70-80% of the total composition. To add additional soap basis -10-15%, consisting of sorbitol, glycerine, as well as 2-5% of fruit infusions of 5% in strength, celandine, birch bark, coconut and scents of celandine essential oils and yellow color. Water for dilution of the substrate from 50 to 200% of the solid soap composition. Ingredients are melted at 70-100°C, boiled and mixed on a steam bath for 20 minutes, then the heat is turned off and scents and paint are added, mixed and poured into long oval moulds, are hardening for 72 hours, knocked out of moulds, cut, and the name is stamped.

[0024]Example No.12.Toothpaste The herbal mixture consists of herbal ingredients, such as birch bark, which kills fungal infections, ginger sap and flour from the seeds of black pepper.

The test was conducted on the Huh-7 and gave a positive result.

The mixture is used for various therapeutic compositions, and if it is included in a toothpaste, it prevents and kills microbial caries flora -Stafflococcus A. The manufacturing method is the following -ingredients, which constitute 70-90% of the total composition of a paste -calcium carbonate, silicon dioxide, sorbitol, sodium lauryl sulfate, carbossimetilcellulose are put in the vessel, poured with water to the desired thickness and boiled at 80°C for 3 minutes. Saccharin, glucose, vegetable extract of I or 10% in strength -5-10% -are added into hot mass, in accordance with the described technology, as well as the essential oils of black pepper and ginger. [0025}Example No. 13. Soap-cream Use of the product is used against radiation. The mixture consists of leaves and seeds of herbal products, extracts of geerah, mint, garlic, fir, coconut of 1% and 10% in strength. Manufactured by hot Technique No. 1. To melt the olive oil 50%, peach 50% at 70-100°C -70-80%.

To add additional soap basis -10-15%, consisting of extracts of the following herbals on the basis of the phosphate, warmed to 50°C for 30 minutes and kept for 18 hours at 37°C -garlic, geerah, mint, fir, coconut.

Then to add coconut, blue clay, glycerin, fir essential oils, mint, dark blue color -2-5%. Water for dilution of the substrate from 50 to 200% of the solid soap composition. Ingredients are melted at 70-100°C, boiled and mixed on a steam bath for 20 minutes, then the heat is turned off and scents and paint are added, mixed and poured into long oval moulds, are hardening for 48 hours, lcnocked out of moulds and cut.

[0026]Example No. 14. Alcoholate for skin.

Herbal mixture is used against MCF-7, Huh-7, artluagra, kidney cancer, prevents skin cancer, fungal infections, herpes, burns from irradiation increases immunity. The strength of the extract should be 5%, 10%, 20% or 40%.

Prepared from previously processed plants in accordance with the method No. 2 for extraction of enzymes infused on phosphate buffer or methyl vodka, heated to 50 °C for 30 minutes and incubated at 37 °C for 18 hours in a thermostat from --red pepper, red poppy, red peony flowers, lilac Hungarian, mix curry. Hrizontemy, a red sage, asparagus, birch bark, eucalyptus, orange zest, thyme, lemongrass red, licorice which make 10-20% of the total volume. With the liquid this part makes 50-60% of the total volume of the product. Then add to the buckthorn and flax oil, flax, which make 20-30% of the total of volume. Distilled water makes 50-100% According to the 1st and 3" parts of the method, essential oils, which are containing CIOH120 in to Chrysanthemum and Eukaliptus.the block primarily the transfer of RNA virus to a healthy cell.Finally the product is centrifuged three times for 5 minutes at 9000 rpm, filtered by filters (22mp) for the extract sterility.Preparation of extracts is described in the paragraph of safety testing. [0027]Example No.15. Ointment The ointment consists of 65-80% glycerin of the total composition; 10-20% olive and buckthorn oil,wthich included 10-20% from all substance.And 10% extracts,wthich was prepared in accordance with the method No. 2, while activating enzymes at 65 °C (page No.10,22); seeds of geerah juniper, black pepper, mustard, coriander, barberry, flax, cloves, cardamom. Strength is regulated up to 1%, 5%, 10%. Applied for the mucous membranes and skin in case of dryness, irradiation and radiation. Tested on Huh-7,MCF-7.

[0028]Example No.16 Sulfur ointment with extracts.

Sulfur ointment with extracts of ginger, black pepper, birch bark, 5% tincture of iodine, buckthorn oil and 5% ginseng tincture. Extracts should be of 1 and 10%.

Tested on MCF-7.B6-F10. Technology is the following from the No. 6: -98% sulfur ointment melted in the vat at 60 °C for 5-10 minutes, add a mixture of 2 to 7% of the above mentioned extracts prepared according to the technology described in the chapter about safety testingTurn off the heat, filter, pour in tubas 400291Safety Testing and Results.

Aptitude tests and the tests of the above described properties of antiproliferative properties were carried out in molecular biology institute. Tests were carried out mainly on the basis of such models as MCF-7, Huh-7, B16-F10 (ATCC, Sweden), seeded into 24-well plate, in quantity of 10, raising to the 5th power, per well, for /MCF-7/, Dulbeccos Minimal Essential Medium, for B16-FI OD -Calf serum and 2Mm L-glutamine -10%, for /Huh-7/ calf serum -10%, gentamicin -40mg/ml, MTT by the cytogenetic test (SigmaUSA) on the antiproliferative properties of the patentable substances of herbals and chemicals.

Viability was examined by MTT TEST-/Sigma-USA!. According to the manufacturer's instructions, cell cultures were incubated with the extracts for 48 hours, then the cell medium was changed to bromid 3 -(4,5-dimethylthiazole) 2,5 tetrazolium (MTT), containing the solution, and the cells were incubated for 2 hours at 37°C.Living cells are able to convert the soluble yellow MIT to insoluble purple-blue intracellular crystals of formazine, but the dead cells are not able. After incubation, the solution containing formazine, was dissolved by the solution containing isopropanol, optical density was measured by the spectrometer. Viability was determined by the formula (test570nm-620nm) /(contro1570nm620nm)*100.Herbal extracts were mixed with phosphate buffer -1:10, incubated at 50°C and 60*C for 30 minutes and at 37°C for 18 hoursACentrifuged3 type. for 5 minutes (9000 rpm), filtered by filters (22mp) for sterility of the extractand gave antiproliferative positive effect, which can be seen from graphs. Several mixtures were taken for that: [0030]Mixture No.1 -seeds of geerah juniper, black pepper, mustard, coriander, barberry, flax, cloves, cardamom. Mixture No. 2 -cardamom seeds, Mixture No. 3 -seeds of cardamon, cloves, coriander. MCF-7

The dermatological tests have been also conducted.

Especially since the use of zinc, clove and other oils and antiprotozoal drugs has previously neutralized many human pathogens.

[00311Aprolication technique.

Antibacterial soap is applied to a preheated and moistened skin, soaped and stirred for 1-5 minutes, and then washed off with cold water.The present invention is effective in daily use for the prevention of various infections and removal of make-up and dirt. Relaxes and heals the skin, removes tension and fatigue, improves immunity, prevents the emergence of a variety of infections. The buyer deals with drugs should consult a doctor or specialist in case of complaints. The present invention illustrates and reveals the features of the fight against skin diseases and the prevention of skin aging. The present invention includes all equivalents that are allowed by the law and used by experienced professionals.

160.0M 140.0 7 (htmian. bra telifention after treatment with 120.0 100.0 80.0 6.0 40.0 20.0 0.0 000 53 Si) 19 1.34.5 95.5 117.2 S3.5 28,7 819 113!

Claims (5)

1. FORMULA1. The composition for cleansing, pealing of dead cells, epidermis rejuvenation, prevention of the occurrence of skin diseases, and is presented in the form of soap, scrub, cream, paste, tinctures.
2. 2. The composition according to No. 1 includes,that specific antitumour substances of the herbals (alkaloids, proteins, acids, oils, terpenes) affect the virus RNA, DNA and then affect the tumoral genes and produce protective antibodies
3. 3. The composition according to No. 1 includes some types of plants, which block viral RNA, bacterial, RNA oncogenic, protect the skin from premature aging, infection, radiation injuries by increasing immunity and they mixtures may be used separately without any limitations in therapeutic compositions
4. 4. The composition according to Nol differs with the fact that the invention relates to new therapeutic compositions, which are used for the fight diseases skin diseases, as well as cancerous affects, include antiprotozoal drugs (nystatin, metronidazole), which removes too accumulated chitin, cellulose, fungal flora and the type of spg, bacteria, which mainly form the alveolar carcinomas.
5. 5. The therapeutic composition of all recipes consists of Na, K salts of fatty acids of vegetable and animal fats and salmons composes -80-90%, unrefined vegetable oils -olive, palm, sunflower, peach, coriander, flax, fir -10-15%; thickeners (sorbitol, glycerine, albihtol, chalk, paraffin, vegetable flour) -10-15%; herbal material (seeds) and their chemical equivalent, essential oils, flavouring, alcohol, paint, antibiotic and antiprotozoal drugs -0,001-0,10%, distilled or purified water -50-200% of the solid composition of the product, the entire composition composes 100%.

   6, Therapeutic composition according to item N21 is characterized by the fact that it provides the same method, which helps to identify and select the medicated mixtures and substances, as well as by similarity of the chemical formula of the infection and antiproliferative substances, which block the expansion of RNA viruses, oncogenes, metastasis, as well as biological and chemical mixtures, which are included in the compositions of the cream, toothpaste, soap, scrub, preventing the occurrence of these infections.