GB2529279B - Hybrid acquisition method incorporating multiple dissociation techniques - Google Patents

Hybrid acquisition method incorporating multiple dissociation techniques

Info

Publication number
GB2529279B
GB2529279B GB1506528.7A GB201506528A GB2529279B GB 2529279 B GB2529279 B GB 2529279B GB 201506528 A GB201506528 A GB 201506528A GB 2529279 B GB2529279 B GB 2529279B
Authority
GB
United Kingdom
Prior art keywords
acquisition method
incorporating multiple
method incorporating
dissociation techniques
hybrid acquisition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1506528.7A
Other versions
GB2529279A (en
GB201506528D0 (en
Inventor
Mark Brown Jeffery
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority to GB1705952.8A priority Critical patent/GB2551614B/en
Publication of GB201506528D0 publication Critical patent/GB201506528D0/en
Publication of GB2529279A publication Critical patent/GB2529279A/en
Application granted granted Critical
Publication of GB2529279B publication Critical patent/GB2529279B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0081—Tandem in time, i.e. using a single spectrometer
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1506528.7A 2014-04-17 2015-04-17 Hybrid acquisition method incorporating multiple dissociation techniques Active GB2529279B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1705952.8A GB2551614B (en) 2014-04-17 2015-04-17 Hybrid acquisition method incorporating multiple dissociation techniques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1406981.9A GB201406981D0 (en) 2014-04-17 2014-04-17 Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation

Publications (3)

Publication Number Publication Date
GB201506528D0 GB201506528D0 (en) 2015-06-03
GB2529279A GB2529279A (en) 2016-02-17
GB2529279B true GB2529279B (en) 2017-05-31

Family

ID=50928950

Family Applications (3)

Application Number Title Priority Date Filing Date
GBGB1406981.9A Ceased GB201406981D0 (en) 2014-04-17 2014-04-17 Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation
GB1506528.7A Active GB2529279B (en) 2014-04-17 2015-04-17 Hybrid acquisition method incorporating multiple dissociation techniques
GB1705952.8A Active GB2551614B (en) 2014-04-17 2015-04-17 Hybrid acquisition method incorporating multiple dissociation techniques

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1406981.9A Ceased GB201406981D0 (en) 2014-04-17 2014-04-17 Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1705952.8A Active GB2551614B (en) 2014-04-17 2015-04-17 Hybrid acquisition method incorporating multiple dissociation techniques

Country Status (1)

Country Link
GB (3) GB201406981D0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9911585B1 (en) * 2016-12-21 2018-03-06 Thermo Finnigan Llc Data-independent mass spectral data acquisition including data-dependent precursor-ion surveys
GB2561378B (en) * 2017-04-12 2022-10-12 Micromass Ltd Optimised targeted analysis

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060169892A1 (en) * 2005-01-28 2006-08-03 Hitachi High-Technologies Corporation Mass spectrometer
US20070158544A1 (en) * 2005-12-22 2007-07-12 Bruker Daltonik Gmbh Feedback fragmentation in ion trap mass spectrometers
US20080048110A1 (en) * 2006-08-22 2008-02-28 Hitachi High-Technologies, Corporation Methods and instruments for identification of glycosylated proteins and peptides
US20090072132A1 (en) * 2007-09-13 2009-03-19 Naomi Manri Mass spectroscopy system and mass spectroscopy method
WO2013005060A2 (en) * 2011-07-06 2013-01-10 Micromass Uk Limited Photo-dissociation of proteins and peptides in a mass spectrometer
WO2013144708A1 (en) * 2012-03-28 2013-10-03 Dh Technologies Development Pte. Ltd. Mass spectrometry systems and methods for analyses on lipid and other ions using a unique workflow
WO2013171459A2 (en) * 2012-05-18 2013-11-21 Micromass Uk Limited Method of identifying precursor ions
GB2523222A (en) * 2013-11-12 2015-08-19 Micromass Ltd Method of correlating precursor and fragment ions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0523811D0 (en) * 2005-11-23 2006-01-04 Micromass Ltd Mass stectrometer
GB0609253D0 (en) * 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer
US20110006200A1 (en) * 2009-07-07 2011-01-13 Dh Technologies Development Pte. Ltd. Methods And Apparatus For Mass Spectrometry With High Sample Utilization

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060169892A1 (en) * 2005-01-28 2006-08-03 Hitachi High-Technologies Corporation Mass spectrometer
US20070158544A1 (en) * 2005-12-22 2007-07-12 Bruker Daltonik Gmbh Feedback fragmentation in ion trap mass spectrometers
US20080048110A1 (en) * 2006-08-22 2008-02-28 Hitachi High-Technologies, Corporation Methods and instruments for identification of glycosylated proteins and peptides
US20090072132A1 (en) * 2007-09-13 2009-03-19 Naomi Manri Mass spectroscopy system and mass spectroscopy method
WO2013005060A2 (en) * 2011-07-06 2013-01-10 Micromass Uk Limited Photo-dissociation of proteins and peptides in a mass spectrometer
WO2013144708A1 (en) * 2012-03-28 2013-10-03 Dh Technologies Development Pte. Ltd. Mass spectrometry systems and methods for analyses on lipid and other ions using a unique workflow
WO2013171459A2 (en) * 2012-05-18 2013-11-21 Micromass Uk Limited Method of identifying precursor ions
GB2523222A (en) * 2013-11-12 2015-08-19 Micromass Ltd Method of correlating precursor and fragment ions

Also Published As

Publication number Publication date
GB2551614A (en) 2017-12-27
GB201705952D0 (en) 2017-05-31
GB201406981D0 (en) 2014-06-04
GB2529279A (en) 2016-02-17
GB2551614B (en) 2018-09-05
GB201506528D0 (en) 2015-06-03

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