GB2528070B - Nerve stimulating and monitoring device - Google Patents

Nerve stimulating and monitoring device

Info

Publication number
GB2528070B
GB2528070B GB1412137.0A GB201412137A GB2528070B GB 2528070 B GB2528070 B GB 2528070B GB 201412137 A GB201412137 A GB 201412137A GB 2528070 B GB2528070 B GB 2528070B
Authority
GB
United Kingdom
Prior art keywords
monitoring device
nerve stimulating
nerve
stimulating
monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1412137.0A
Other versions
GB201412137D0 (en
GB2528070A (en
Inventor
Eftekhar Amir
Toumazou Christofer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VAGONYX Ltd
Original Assignee
VAGONYX Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VAGONYX Ltd filed Critical VAGONYX Ltd
Priority to GB1412137.0A priority Critical patent/GB2528070B/en
Publication of GB201412137D0 publication Critical patent/GB201412137D0/en
Priority to PCT/EP2015/065511 priority patent/WO2016005400A1/en
Publication of GB2528070A publication Critical patent/GB2528070A/en
Application granted granted Critical
Publication of GB2528070B publication Critical patent/GB2528070B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4041—Evaluating nerves condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05—Surgical care
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/028—Microscale sensors, e.g. electromechanical sensors [MEMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6877—Nerve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4148—Integrated circuits therefor, e.g. fabricated by CMOS processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G01N33/4836—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures using multielectrode arrays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physiology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Electrotherapy Devices (AREA)
GB1412137.0A 2014-07-08 2014-07-08 Nerve stimulating and monitoring device Active GB2528070B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1412137.0A GB2528070B (en) 2014-07-08 2014-07-08 Nerve stimulating and monitoring device
PCT/EP2015/065511 WO2016005400A1 (en) 2014-07-08 2015-07-07 Nerve stimulating and monitoring device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1412137.0A GB2528070B (en) 2014-07-08 2014-07-08 Nerve stimulating and monitoring device

Publications (3)

Publication Number Publication Date
GB201412137D0 GB201412137D0 (en) 2014-08-20
GB2528070A GB2528070A (en) 2016-01-13
GB2528070B true GB2528070B (en) 2016-12-14

Family

ID=51410803

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1412137.0A Active GB2528070B (en) 2014-07-08 2014-07-08 Nerve stimulating and monitoring device

Country Status (2)

Country Link
GB (1) GB2528070B (en)
WO (1) WO2016005400A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101700886B1 (en) * 2015-07-24 2017-02-01 한국과학기술연구원 Neural probe array of high performance and for minimized damage of neuron
ES2862458T3 (en) 2016-10-04 2021-10-07 Ecole Polytechnique Fed Lausanne Epfl Intrafascicular lead implant
KR101887024B1 (en) * 2016-11-10 2018-08-09 한국과학기술연구원 Neural Probe Structure and Neural Probe Assembly having the same
GB2563651A (en) * 2017-06-22 2018-12-26 Galvani Bioelectronics Ltd Nerve stimulation and monitoring device
US11672972B2 (en) 2017-12-21 2023-06-13 Galvani Bioelectronics Limited Nerve stimulation device for unidirectional stimulation and current steering
EP3727562A1 (en) * 2017-12-21 2020-10-28 Galvani Bioelectronics Limited Nerve stimulation device for current steering
CN112969918A (en) * 2018-09-21 2021-06-15 特拉利蒂克股份有限公司 Scalable multimodal sensor fusion platform for remote near field sensing

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1726329A1 (en) * 2005-05-25 2006-11-29 Alfred E. Mann Foundation for Scientific Research Hermetically sealed three-dimensional electrode array
WO2008007065A2 (en) * 2006-07-10 2008-01-17 Imperial Innovations Limited Method and apparatus for measuring activity in the peripheral nervous system
US7991475B1 (en) * 2005-06-08 2011-08-02 The Regents Of The University Of California High density micromachined electrode arrays useable for auditory nerve implants and related methods
GB2487416A (en) * 2011-01-21 2012-07-25 Dna Electronics Ltd Chemical Sensor
US20130253299A1 (en) * 2012-03-20 2013-09-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring and regulating physiological states and functions via sensory neural inputs to the spinal cord

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4969468A (en) * 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
US5400784A (en) * 1993-10-15 1995-03-28 Case Western Reserve University Slowly penetrating inter-fascicular nerve cuff electrode and method of using
US20130046148A1 (en) * 2009-11-09 2013-02-21 Prashant Tathireddy Three Dimensional Penetrating Optical-Electrical Neural Interface for Selective Stimulation and Recording

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1726329A1 (en) * 2005-05-25 2006-11-29 Alfred E. Mann Foundation for Scientific Research Hermetically sealed three-dimensional electrode array
US7991475B1 (en) * 2005-06-08 2011-08-02 The Regents Of The University Of California High density micromachined electrode arrays useable for auditory nerve implants and related methods
WO2008007065A2 (en) * 2006-07-10 2008-01-17 Imperial Innovations Limited Method and apparatus for measuring activity in the peripheral nervous system
GB2487416A (en) * 2011-01-21 2012-07-25 Dna Electronics Ltd Chemical Sensor
US20130253299A1 (en) * 2012-03-20 2013-09-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring and regulating physiological states and functions via sensory neural inputs to the spinal cord

Also Published As

Publication number Publication date
WO2016005400A1 (en) 2016-01-14
GB201412137D0 (en) 2014-08-20
GB2528070A (en) 2016-01-13

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