GB2527876B - Confirmation using multiple collision cross section ("CCS") Measurements - Google Patents

Confirmation using multiple collision cross section ("CCS") Measurements

Info

Publication number
GB2527876B
GB2527876B GB1504033.0A GB201504033A GB2527876B GB 2527876 B GB2527876 B GB 2527876B GB 201504033 A GB201504033 A GB 201504033A GB 2527876 B GB2527876 B GB 2527876B
Authority
GB
United Kingdom
Prior art keywords
ccs
confirmation
measurements
section
collision cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1504033.0A
Other versions
GB201504033D0 (en
GB2527876A (en
Inventor
Giles Kevin
Raymond Green Martin
George Richardson Keith
Lee Wildgoose Jason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of GB201504033D0 publication Critical patent/GB201504033D0/en
Publication of GB2527876A publication Critical patent/GB2527876A/en
Application granted granted Critical
Publication of GB2527876B publication Critical patent/GB2527876B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
GB1504033.0A 2014-03-10 2015-03-10 Confirmation using multiple collision cross section ("CCS") Measurements Active GB2527876B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201404195A GB201404195D0 (en) 2014-03-10 2014-03-10 Confirmation using multiple CCS measurements

Publications (3)

Publication Number Publication Date
GB201504033D0 GB201504033D0 (en) 2015-04-22
GB2527876A GB2527876A (en) 2016-01-06
GB2527876B true GB2527876B (en) 2018-05-23

Family

ID=50554805

Family Applications (5)

Application Number Title Priority Date Filing Date
GB201404195A Ceased GB201404195D0 (en) 2014-03-10 2014-03-10 Confirmation using multiple CCS measurements
GB1504071.0A Active GB2527879B (en) 2014-03-10 2015-03-10 Using theoretical collision cross section ("CCS") in sample identification
GB1504070.2A Active GB2527632B (en) 2014-03-10 2015-03-10 Unknown identification using theroretical collision cross section
GB1504069.4A Active GB2527878B (en) 2014-03-10 2015-03-10 Theoretical collision cross section ("CCS") in experimental design
GB1504033.0A Active GB2527876B (en) 2014-03-10 2015-03-10 Confirmation using multiple collision cross section ("CCS") Measurements

Family Applications Before (4)

Application Number Title Priority Date Filing Date
GB201404195A Ceased GB201404195D0 (en) 2014-03-10 2014-03-10 Confirmation using multiple CCS measurements
GB1504071.0A Active GB2527879B (en) 2014-03-10 2015-03-10 Using theoretical collision cross section ("CCS") in sample identification
GB1504070.2A Active GB2527632B (en) 2014-03-10 2015-03-10 Unknown identification using theroretical collision cross section
GB1504069.4A Active GB2527878B (en) 2014-03-10 2015-03-10 Theoretical collision cross section ("CCS") in experimental design

Country Status (1)

Country Link
GB (5) GB201404195D0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11226309B2 (en) * 2019-04-15 2022-01-18 Waters Technologies Ireland Limited Techniques for predicting collision cross-section values
GB202001249D0 (en) * 2020-01-29 2020-03-11 Waters Technologies Ireland Ltd Techniques for sample analysis using product ion collision-cross section information

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495824B1 (en) * 2000-03-13 2002-12-17 Bechtel Bwxt Idaho, Llc Ion mobility spectrometer, spectrometer analyte detection and identification verification system, and method
WO2004012231A2 (en) * 2002-07-25 2004-02-05 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
GB2393849A (en) * 2002-07-31 2004-04-07 Gen Electric Ion mobility spectrometer with a switchable drift field voltage
WO2006114580A1 (en) * 2005-04-23 2006-11-02 Smiths Detection-Watford Limited Ion mobility spectrometer
US20070114382A1 (en) * 2005-11-23 2007-05-24 Clemmer David E Ion mobility spectrometer
WO2008005283A2 (en) * 2006-06-29 2008-01-10 Sionex Corporation Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis
US20100127166A1 (en) * 2008-02-05 2010-05-27 Excellims Corporation Method and apparatus for chemical and biological sample separation
US20130009053A1 (en) * 2006-02-14 2013-01-10 Excellims Corporation Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100224770A1 (en) * 2009-03-06 2010-09-09 Ensco, Inc. Method for configuring an ion mobility spectrometer system
WO2011128703A1 (en) * 2010-04-15 2011-10-20 Micromass Uk Limited Ion mobility method and apparatus for identifying and/or characterising a sample compound
US8278620B2 (en) * 2010-05-03 2012-10-02 Thermo Finnigan Llc Methods for calibration of usable fragmentation energy in mass spectrometry
US8525106B2 (en) * 2011-05-09 2013-09-03 Bruker Daltonics, Inc. Method and apparatus for transmitting ions in a mass spectrometer maintained in a sub-atmospheric pressure regime

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495824B1 (en) * 2000-03-13 2002-12-17 Bechtel Bwxt Idaho, Llc Ion mobility spectrometer, spectrometer analyte detection and identification verification system, and method
WO2004012231A2 (en) * 2002-07-25 2004-02-05 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
GB2393849A (en) * 2002-07-31 2004-04-07 Gen Electric Ion mobility spectrometer with a switchable drift field voltage
WO2006114580A1 (en) * 2005-04-23 2006-11-02 Smiths Detection-Watford Limited Ion mobility spectrometer
US20070114382A1 (en) * 2005-11-23 2007-05-24 Clemmer David E Ion mobility spectrometer
US20130009053A1 (en) * 2006-02-14 2013-01-10 Excellims Corporation Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
WO2008005283A2 (en) * 2006-06-29 2008-01-10 Sionex Corporation Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis
US20100127166A1 (en) * 2008-02-05 2010-05-27 Excellims Corporation Method and apparatus for chemical and biological sample separation

Also Published As

Publication number Publication date
GB2527878A (en) 2016-01-06
GB201504033D0 (en) 2015-04-22
GB2527632B (en) 2018-05-30
GB201504069D0 (en) 2015-04-22
GB201504070D0 (en) 2015-04-22
GB201504071D0 (en) 2015-04-22
GB2527876A (en) 2016-01-06
GB201404195D0 (en) 2014-04-23
GB2527879B (en) 2018-09-12
GB2527879A (en) 2016-01-06
GB2527878B (en) 2018-02-28
GB2527632A (en) 2015-12-30

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