GB2527635B - Liquid extraction matrix assisted laser desorption ionisation ion source - Google Patents

Liquid extraction matrix assisted laser desorption ionisation ion source

Info

Publication number
GB2527635B
GB2527635B GB1504606.3A GB201504606A GB2527635B GB 2527635 B GB2527635 B GB 2527635B GB 201504606 A GB201504606 A GB 201504606A GB 2527635 B GB2527635 B GB 2527635B
Authority
GB
United Kingdom
Prior art keywords
ion source
liquid extraction
laser desorption
assisted laser
matrix assisted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1504606.3A
Other versions
GB201504606D0 (en
GB2527635A (en
Inventor
Mark Brown Jeffery
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of GB201504606D0 publication Critical patent/GB201504606D0/en
Publication of GB2527635A publication Critical patent/GB2527635A/en
Application granted granted Critical
Publication of GB2527635B publication Critical patent/GB2527635B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1504606.3A 2014-03-18 2015-03-18 Liquid extraction matrix assisted laser desorption ionisation ion source Active GB2527635B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1404847.4A GB201404847D0 (en) 2014-03-18 2014-03-18 Liquid extraction matrix assisted laser desorption ionisation ion source

Publications (3)

Publication Number Publication Date
GB201504606D0 GB201504606D0 (en) 2015-05-06
GB2527635A GB2527635A (en) 2015-12-30
GB2527635B true GB2527635B (en) 2018-05-30

Family

ID=50634981

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1404847.4A Ceased GB201404847D0 (en) 2014-03-18 2014-03-18 Liquid extraction matrix assisted laser desorption ionisation ion source
GB1504606.3A Active GB2527635B (en) 2014-03-18 2015-03-18 Liquid extraction matrix assisted laser desorption ionisation ion source

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1404847.4A Ceased GB201404847D0 (en) 2014-03-18 2014-03-18 Liquid extraction matrix assisted laser desorption ionisation ion source

Country Status (1)

Country Link
GB (2) GB201404847D0 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010033809A1 (en) * 1997-05-23 2001-10-25 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
US20050056776A1 (en) * 2000-06-09 2005-03-17 Willoughby Ross C. Laser desorption ion source
US20110049352A1 (en) * 2009-09-02 2011-03-03 Li Ding Ion source
US20120079894A1 (en) * 2010-10-01 2012-04-05 Ut-Battelle, Llc Systems and methods for laser assisted sample transfer to solution for chemical analysis
US20130214154A1 (en) * 2010-09-02 2013-08-22 Wayne State University System and method for ionization of molecules for mass spectrometry and ion mobility spectrometry
US20140070088A1 (en) * 2012-09-07 2014-03-13 Canon Kabushiki Kaisha Ionization device, mass spectrometer including the ionization device, and image generation system including the ionization device
GB2511643A (en) * 2013-03-05 2014-09-10 Micromass Ltd Charging plate for enhancing multiply charged ions by laser desportion
WO2014135864A1 (en) * 2013-03-05 2014-09-12 Micromass Uk Limited Charging plate for enhancing multiply charged ions by laser desorption

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010033809A1 (en) * 1997-05-23 2001-10-25 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
US20050056776A1 (en) * 2000-06-09 2005-03-17 Willoughby Ross C. Laser desorption ion source
US20110049352A1 (en) * 2009-09-02 2011-03-03 Li Ding Ion source
US20130214154A1 (en) * 2010-09-02 2013-08-22 Wayne State University System and method for ionization of molecules for mass spectrometry and ion mobility spectrometry
US20120079894A1 (en) * 2010-10-01 2012-04-05 Ut-Battelle, Llc Systems and methods for laser assisted sample transfer to solution for chemical analysis
US20140070088A1 (en) * 2012-09-07 2014-03-13 Canon Kabushiki Kaisha Ionization device, mass spectrometer including the ionization device, and image generation system including the ionization device
GB2511643A (en) * 2013-03-05 2014-09-10 Micromass Ltd Charging plate for enhancing multiply charged ions by laser desportion
WO2014135864A1 (en) * 2013-03-05 2014-09-12 Micromass Uk Limited Charging plate for enhancing multiply charged ions by laser desorption

Also Published As

Publication number Publication date
GB201504606D0 (en) 2015-05-06
GB2527635A (en) 2015-12-30
GB201404847D0 (en) 2014-04-30

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