GB2513811A - Pest And Pathogen Control - Google Patents

Pest And Pathogen Control Download PDF

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Publication number
GB2513811A
GB2513811A GB1415502.2A GB201415502A GB2513811A GB 2513811 A GB2513811 A GB 2513811A GB 201415502 A GB201415502 A GB 201415502A GB 2513811 A GB2513811 A GB 2513811A
Authority
GB
United Kingdom
Prior art keywords
insect
bacterial cell
pest
pathogen control
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1415502.2A
Other versions
GB201415502D0 (en
Inventor
Paul Dyson
Miranda Whitten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Swansea University
Original Assignee
Swansea University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swansea University filed Critical Swansea University
Publication of GB201415502D0 publication Critical patent/GB201415502D0/en
Publication of GB2513811A publication Critical patent/GB2513811A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/32—Special delivery means, e.g. tissue-specific
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/50—Biochemical production, i.e. in a transformed host cell
    • C12N2330/51—Specially adapted vectors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Abstract

The invention concerns a genetically transformed or transfected bacterial cell wherein said bacteria is a gut symbiont of an insect vector or insect pest; characterised in that said bacterial cell is transformed to express dsRNA against at least one selected target gene of the insect vector, whereby the effect or viability of said insect is deleteriously compromised; also an insect including said bacterial cell and a method of modulating a target insect gene using said bacterial cell.
GB1415502.2A 2012-02-08 2013-02-01 Pest And Pathogen Control Withdrawn GB2513811A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1202119.2A GB201202119D0 (en) 2012-02-08 2012-02-08 Pest and pathogen control
PCT/GB2013/050228 WO2013117910A1 (en) 2012-02-08 2013-02-01 Pest and pathogen control

Publications (2)

Publication Number Publication Date
GB201415502D0 GB201415502D0 (en) 2014-10-15
GB2513811A true GB2513811A (en) 2014-11-05

Family

ID=45896761

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1202119.2A Ceased GB201202119D0 (en) 2012-02-08 2012-02-08 Pest and pathogen control
GB1415502.2A Withdrawn GB2513811A (en) 2012-02-08 2013-02-01 Pest And Pathogen Control

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1202119.2A Ceased GB201202119D0 (en) 2012-02-08 2012-02-08 Pest and pathogen control

Country Status (2)

Country Link
GB (2) GB201202119D0 (en)
WO (1) WO2013117910A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10329560B2 (en) 2013-09-23 2019-06-25 Georgia Tech Research Corporation Targeting non-coding RNA for RNA interference
GB201510154D0 (en) * 2015-06-11 2015-07-29 Univ Swansea Pest control system
GB201519734D0 (en) 2015-11-09 2015-12-23 Univ Swansea Cancer therapy
AU2017233862B2 (en) 2016-03-15 2023-04-13 Rnaissance Ag Llc Methods and compositions for increased double stranded RNA production
MX2019002949A (en) 2016-09-16 2020-01-27 Pebble Labs Usa Inc Novel paratransgenic system for the biocontrol of disease-transmitting mosquitos.
EP3573465A4 (en) * 2017-01-24 2020-11-04 Flagship Pioneering Innovations V, Inc. Methods and related compositions for manufacturing food and feed

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005110068A2 (en) * 2004-04-09 2005-11-24 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347759B1 (en) 2006-01-12 2017-10-18 deVGen N.V. Methods for controlling pests using RNAi
CA2806295A1 (en) 2009-08-03 2011-02-10 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating insects
BR122018067960B8 (en) 2009-08-28 2022-12-06 Du Pont ISOLATED POLYNUCLEOTIDE, EXPRESSION CASSETTE, METHOD FOR CONTROLLING A PLAST PEST OF THE COLEOPTERA TYPE AND METHOD FOR OBTAINING A PLANT
IT1399742B1 (en) 2009-09-25 2013-05-03 Arterra Bioscience S R L INACTIVATED MICRO-ORGANISMS CONTAINING RNA MOLECULES WITH DOUBLE FILAMENT (DSRNA), THEY USE AS PESTICIDES AND METHODS FOR THEIR PREPARATION

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005110068A2 (en) * 2004-04-09 2005-11-24 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ARAUJO R N ET AL: "RNA interference of the salivary gland nitrophorin 2 in the triatomine bug Rhodnius prolixus (Hemiptera: Reduviidae) by dsRNA ingestion or injection", INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, ELSEVIER SCIENCE LTD, GB, vol. 36, no. 9, 13 June 2006 (2006-06-13), pages 683-693, XP0 *
COUTINHO-ABREU I V ET AL: "Transgenesis and paratransgenesis to control insect-borne diseases: Current status and future challenges", PARASITOLOGY INTERNATIONAL, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 59, no. 1, 9 October 2009 (2009-10-09), pages 1-8, XP026906417, ISSN: 1383-5769, DOI: 10.1016/J.PARI *
ELLEN M DOTSON ET AL: "Transformation of Rhodococcus rhodnii, a symbiont of the Chagas disease vector Rhodnius prolixus, with integrative elements of the L1 mycobacteriophage", INFECTION, GENETICS AND EVOLUTION, vol. 3, no. 2, 24 January 2003 (2003-01-24), pages 103-109, XP055061120, ISSN: 1567-1348 *
HE LIN ET AL: "PcnB is required for the rapid degradation of RNAI, the antisense RNA that controls the copy number of ColE1-related plasmids", MOLECULAR MICROBIOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 9, no. 6, 1 January 1993 (1993-01-01) , pages 1131-1142, XP002568715, ISSN: 0950-382X, DOI: *
HUVENNE H ET AL: "Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: A review", JOURNAL OF INSECT PHYSIOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 56, no. 3, 9 October 2009 (2009-10-09), pages 227-235, XP026889277, ISSN: 0022-1910, DOI: 10.1016/J.JINSPHYS.2009.10.004 [retrieve *
IVY HURWITZ ET AL: "Paratransgenic control of vector borne diseases", INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, vol. 7, no. 9, 1 November 2011 (2011-11-01), pages 1334-1344, XP055061147, ISSN: 1449-2288 *
MARTIN K. RONO ET AL: "The Major Yolk Protein Vitellogenin Interferes with the Anti-Plasmodium Response in the Malaria Mosquito Anopheles gambiae", PLOS BIOLOGY, vol. 8, no. 7, 20 July 2010 (2010-07-20), page e1000434, XP055060714, ISSN: 1544-9173, DOI: 10.1371/journal.pbio.1000434 *
R. V. DURVASULA ET AL: "Prevention of insect-borne disease: An approach using transgenic symbiotic bacteria", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 94, no. 7, 1 April 1997 (1997-04-01), pages 3274-3278, XP055061209, ISSN: 0027-8424, DOI: 10.1073/pnas.94.7.3274 *

Also Published As

Publication number Publication date
WO2013117910A1 (en) 2013-08-15
GB201202119D0 (en) 2012-03-21
GB201415502D0 (en) 2014-10-15

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