GB2492941A - An apparatus for filling a syringe - Google Patents

An apparatus for filling a syringe Download PDF

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Publication number
GB2492941A
GB2492941A GB1103571.4A GB201103571A GB2492941A GB 2492941 A GB2492941 A GB 2492941A GB 201103571 A GB201103571 A GB 201103571A GB 2492941 A GB2492941 A GB 2492941A
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GB
United Kingdom
Prior art keywords
text
ampoule
port
housing
valve mechanism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1103571.4A
Other versions
GB201103571D0 (en
Inventor
Mark Eaton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Owen Mumford Ltd
Original Assignee
Owen Mumford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Owen Mumford Ltd filed Critical Owen Mumford Ltd
Priority to GB1103571.4A priority Critical patent/GB2492941A/en
Publication of GB201103571D0 publication Critical patent/GB201103571D0/en
Publication of GB2492941A publication Critical patent/GB2492941A/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2058—Connecting means having multiple connecting ports
    • A61J1/2062—Connecting means having multiple connecting ports with directional valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67B—APPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
    • B67B7/00—Hand- or power-operated devices for opening closed containers
    • B67B7/92—Hand- or power-operated devices for opening closed containers by breaking, e.g. for ampoules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M2039/0205—Access sites for injecting media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

An apparatus comprising a valve mechanism 26, the valve mechanism 26 comprising a first port 8 that can be connected to a syringe 11, a second port 10 that can be connected to a hypodermic needle 21, and a third port. The apparatus further comprises a housing 5 that is configured to receive an ampoule 1, and which housing 5 comprises an interior space in fluid communication with the third port of the valve mechanism 26, and a mechanism for breaking open the ampoule. The housing 5 may have deformable and rigid parts, such that the rigid part holds the ends of the ampoule 1 firmly, while deformation of the deformable part causes the neck of the ampoule 1 to break, releasing the contents.

Description

AN APPARATUS FOR FILLING A SYRINGE
Technical Field
The present invention relates to an apparatus for filling a syringe and in particular to an apparatus for filling a syringe from a frangible ampoule.
Backciround Liquid medications are commonly provided in ampoules. Ampoules are typically made of glass, although plastic ampoules do exist. Ampoules are most commonly used to contain pharmaceuticals and chemicals that must be protected from air and contaminants. Ampoules dimensions can be a de facto standard within the pharmaceutical industry for containing measured doses of sterile medicine, particularly for injectable medicines. During manufacture, after the required dose of medicine has been dispensed into the ampoule, the remaining space is usually filled with an inert gas before the top is sealed by melting the glass shut. In order to inject the medicine, a user must first break open the ampoule and draw the medicine up from the ampoule into a syringe using a needle.
Figure 1 shows a typical glass ampoule 1. The ampoule is opened by snapping off a top portion 2 at the neck of the ampoule 4. The neck 4 is an area with a reduced diameter which is positioned between the top portion 2 and the larger bottom portion of the ampoule 3. The neck 4 is intended to allow the ampoule 1 to be opened with a clean break in the glass and without creating any glass shards or slivers, but in practice a clean break rarely occurs. Consequently, the person using the ampoule must be careful not to injure themselves on broken glass as well as ensuring that no pieces of glass get into the liquid inside the ampoule.
In addition to the dangers that can arise from the ampoule itself, transferring the liquid from an ampoule into a syringe also poses risks to the user. Once the top of the ampoule 2 has been snapped off, the user must hold the bottom portion of the ampoule 3 in one hand, and guide the needle of a syringe into the opening in order to draw the contents up into the syringe. As the necks of glass ampoules tend to be slim in order to ease in the snapping off of the top portion 2, the target" for the user to insert the needle into is small. It is easy for the user to miss the opening and, if care is not taken, to injure the hand that is holding the anipoule with the needle, known as a "sticking" injury.
Summary
According to a first aspect of the present invention there is provided an apparatus comprising a valve mechanism, the valve mechanism comprising a first port that can be connected to a syringe, a second port that can be connected to a hypodermic needle, and a third port. The apparatus further comprises a housing that is configured to receive an ampoule, and which housing comprises an interior space in fluid communication with the third port of the valve mechanism, and a mechanism for breaking open the ampoule.
According to an embodiment of the invention, the apparatus may comprise a filter within any fluid path between the housing and the valve mechanism at or adjacent to the third port. The valve mechanism may be configured to allow fluid at any one time to flow only: a) from the third port to the first port; or b) from the first port to the second port.
The valve mechanism may comprise a mechanical switch for selecting one of the two fluid flow pathways a) or b).
The housing may comprise a coupling for coupling the housing with the third port of the valve mechanism such that the housing is in fluid communication with the valve mechanism. The coupling may engage with said mechanical switch such that when the housing is coupled with the third pod the valve mechanism is in state a) and when the housing is uncoupled from the third port the valve mechanism is in state b).
The valve mechanism may comprise a pair of one-way valves.
The housing may define an insertion port through which an ampoule can be inserted into the interior space, with the insertion port comprising a one-way flap valve to inhibit the removal of the ampoule after insertion into the housing.
The mechanism for breaking open the ampoute may comprise a deformabte part and a rigid part such that the rigid part supports the ampoule and when a force is applied to the ampoule by way of the deformable part, the rigid part resists movement and the ampoule is broken.
The inside structure of the housing may comprise a rigid part that supports an ampoule at its top and bottom and leaves it unsupported in the middle.
According to a second aspect of the present invention there is provided a device for releasing fluid from an ampoule, the device comprising a lower part of rigid material and an upper part of deformable material. The upper part and the lower part are connected so as to define an interior space, and one of the upper or lower parts defines an insertion port through which an ampoule can be inserted into the interior space. The lower part is formed to support the ampoule at each end but not in the middle such that when an external force is applied to the upper part, the upper part is deformed towards the ampoule and the force is subsequently applied to the ampoule which breaks in the middle where is it unsupported.
The device may also comprises a port for coupling the device to a valve mechanism such that the interior space is in fluid communication with the valve mechanism. The insertion port may comprise a one-way flap valve to inhibit the removal of the ampoule from the device after insertion.
Brief Description of the Drawings
Figure 1 shows a glass ampoule; Figure 2 shows a perspective view of an embodiment of the invention connected to a hypodermic needle; Figure 3 shows a perspective view of the embodiment of Figure 2 about to be coupled with a syringe; Figure 4 shows a rear perspective view the embodiment of Figures 2 and 3, with the syringe connected, and with a glass ampoule about to be inserted into the housing; Figures 5, 6 and 7 show an embodiment of the invention connected to a needle and a syringe in cross section during three stages of use; and Figure 8, 9 and 10 show perspective views of three stages in the detachment of the housing from the rest of the apparatus.
Detailed Descrirtion As discussed above, ampoules are commonly used to provide measured doses of injectable medicines, but unfortunately broken glass and the risk of "sticking" injuries pose real and serious threats to anyone who has to use them.
WO 2007/105221 describes a fluid transfer device for use with cartridges, which is used to transfer liquid from a cartridge sealed with a pierceable membrane into a syringe. The device contains a syringe port and a cartridge port. The cartridge port includes a puncturing member for puncturing the cartridge's pierceable membrane and for effecting flow communication between the syringe and the cartridge. Also disclosed is a particular valve arrangement ("flow control merriber") which can be changed from an initial flow control position which enables flow communication between the syringe port and a ampoule adapter port, and a subsequent flow control position which enables flow communication between the syringe port and the cartridge port.
It would be extremely beneficial if the operational principles used in WO 2007/105221 could be used with ampoules to help address the problems described above.
The apparatus of the current invention comprises a valve mechanism. The valve mechanism comprises a first port that can be connected to a syringe, a second port that can be connected to a hypodermic needle, and a third port. The first and second pods have standard luer connections that are used to connect with syringes and needles. The valve mechanism has a valve arrangement similar to the flow control member of WO 2007/105221 described above, such that one of two different fluid flow pathways can be in operation at any given time. The first fluid flow pathway is between the third port and the syringe port, and the second fluid flow pathway is between the syringe port and the hypodermic needle port. In one example, the valve mechanism comprises a system of one-way valves arranged such that when the syringe is drawing fluid in, the first fluid flow pathway with the third port is active, but when the syringe is pushing out fluid, the second fluid flow pathway with the hypodermic needle port is active. In an alternative example, one valve is provided which can be manually adjusted to select the desired fluid communication pathway.
The apparatus also comprises an ampoule housing that is suitable to be coupled with the third port of the valve mechanism discussed above. The ampoule housing enables the liquid contents of an ampoule to be easily and safely transferred into a syringe without risking injury to the user from sharp glass or a sticking injury when drawing the fluid into the syringe from the ampoule.
The ampoule housing is best described by considering an example, as shown in Figures 2 to 10. Figure 2 shows an ampoule housing 5 which comprises a lower portion 6 and an upper portion 7. The lower portion 6 is made of a rigid material, for example a thermoplastic, and the upper portion 7 is made of a soft deformable material such as an irradiatable polymer. The housing 5 sits on top of the valve mechanism 26 coupled at its third pod. Figure 2 shows a hypodermic needle with protective cap 9 connected to the valve mechanism 26 via its second pod 10.
Figure 3 shows the apparatus of figure 2 with a syringe 11 about to be inserted into the first port 8. Figure 4 shows a rear perspective view with the ampoule housing, the syringe and the hypodermic needle attached to the three pods on the valve mechanism 26. From the rear perspective view of figure 4, an insertion port 15 in the housing 5 can be seen. This insertion port comprises a "flap valve" with one-way bias facets 16 which permit the ampoule 1 to be inserted into the ampoule housing 5, but which prevent any subsequent removal of the ampoule 1 after insertion. This allows the broken, "spent" ampoule to be disposed of together with the housing in a safe manner and in such a way that the user does not have to handle any broken glass or shards.
The upper portion of the housing 7 will preferably be formed of a transparent material so that the user can see the ampoule inside -and in particular be able to see the markings on the ampoule and also if it has been broken open or not.
Figure 5 shows a cross section of the apparatus connected to a syringe and a hypodermic needle. The syringe 11, which comprises a syringe body 28, and a plunger 29, is connected to the first port 8 of the valve mechanism 26. The hypodermic needle 21 is attached to the second port 10, and is covered by a protective cap 9. A glass ampoule 1 has been inserted into the housing 5 through the insertion port 15.
The lower portion of the housing 6 is provided with angled sides 22 and 23 which support the ampoule at either end. The ampoule 1 contains fluid contents 27. In the middle of the lower portion 6 underneath the middle of the ampoule, there is a reservoir space where, one the ampoule has been broken open, the fluid contents 21 will drain into. A filter 24 positioned at the bottom of the housing 5 will filter the fluid 27 as it passes from the reservoir space through to the channel 25 that connects into the third port of the valve mechanism 26.
In this example, the valve mechanism 26 comprises a valve that can be adjusted to select the desired fluid communication pathway. When in a first state, the valve provides a fluid communication pathway from the third port connected to the housing 5 to the first port 8 connected to the syringe 11. When in a second state, the valve provides a fluid communication pathway from the first port 8 connected to the syringe 11 to the second port 10 connected to the hypodermic needle 21. This allows the fluid from the ampoule 1 that is released into the housing 5 to be drawn into the syringe when the valve is in the first state, and then for the fluid to be administered through the hypodermic needle when the valve is in the second state without any loss of fluid back into the housing 5.
Figure 6 shows the same apparatus of figure 5 with a force F being applied to the top portion of the housing 7. The deformable material allows the top portion of housing 7 to be pressed down towards the ampoule 1. This can be done by a user pushing down with a finger. When inside the ampoule housing, the ampoule 1 is supported at each end by the lower portion of the housing 6 but is not supported in the middle. When the deformed top portion of housing comes into contact with the ampoule and enough force is applied, the ampoule will break at its neck 4, as shown in figure 7. In figure 7, the ampoule is shown in two parts -the top portion 2 having been broken off from lower portion 3 at the neck of the ampoule. The fluid contents have been drained from the ampoule due to gravity. The angled sides 22 and 23 of the lower portion of the housing 6 help in directing the fluid into the reservoir space at the bottom of the housing and towards the flow channel 25. The plunger 29 of the syringe 11 has been pulled back which has drawn the fluid through the filter 24, through the flow channel 25, through the valve mechanism 26 and into body of the syringe 28.
The vatve in the valve mechanism 26 is now switched from its first state as described above to its second state for the fluid to be administered through the hypodermic needle. The housing 5 may be separated and removed from the valve mechanism 26 prior to administering the drug. Figures 8 to 10 show an example which combines the switching of the valve states with the removal of the housing. Figure 8 shows the apparatus with the syringe containing the fluid after it has been drawn up from the ampoule. The protective cap 9 is still covering the hypodermic needle, as it has not needed to be removed yet. This highlights that the use of this apparatus increases safety not only for the user, as the needle does not have to be used to draw the fluid into the syringe from the ampoule, but it also increases the safety of the patient, as the protective cap only needs to be removed at the last minute before injecting the patient, therefore reducing the risk of the needle becoming contaminated outside of the sterile environment of the protective cap.
Figure 9 shows the housing 5 being rotated relative to the valve mechanism 26 about an axis. This rotation, shown as being a rotation of 90°, switches the valve from its first state to its second state, and therefore closing the first fluid communication pathway and opening the second as described above. The rotation of the housing also releases a catch that is holding the housing 5 into connection with the third pod of the valve mechanism 26. By releasing the catch, the housing 5 can be lifted and separated from the valve mechanism, as shown by arrow L in figure 10. The removal of the housing will allow the fluid to be administered without the housing causing any hindrance to the user.
The apparatus can be provided for use in sterile packaging, for example a blister pack, and opened immediately prior to use.
It will be appreciated by the person of skill in the art that various modifications may be made to the above described embodiments without departing from the scope of the invention. For example the upper portion of the housing may be formed from a rigid material, and the insertion port comprises an opening formed by the upper housing being hinged with the lower portion of housing. The ampoule can then be fractured by a section of the upper housing that is adapted to come into contact with the neck of the ampoule on closing the hinged upper portion of housing. Alternatively the housing may be formed as a hollow single piece of deformable material, and the housing itself acts as a mechanism for breaking the ampoule by the user bending the housing.
Furthei filters and non-return valves may be used in the apparatus, for example at any of the ports of the valve mechanism.

Claims (1)

  1. <claim-text>Claims 1. An apparatus comprising a valve mechanism, the valve mechanism comprising: a first port that can be connected to a syringe; a second port that can be connected to a hypodermic needle; and a third port; wherein, the apparatus further comprises a housing that is configured to receive an ampoule, and which housing comprises an interior space in fluid communication with the third port of the valve mechanism, and a mechanism for breaking open the ampoule.</claim-text> <claim-text>2. An apparatus according to claim 1, wherein the apparatus comprises a filter within any fluid path between the housing and the valve mechanism at or adjacent to the third port.</claim-text> <claim-text>3. An apparatus according to claim 1 or 2, wherein the valve mechanism is configured to allow fluid at any one time to flow only: c) from the third port to the first port; or d) from the first port to the second port.</claim-text> <claim-text>4. An apparatus according to claim 3, wherein the valve mechanism comprises a mechanical switch for selecting one of the two fluid flow pathways a) or b).</claim-text> <claim-text>5. An apparatus according to any one of the preceding claims, wherein the housing comprises a coupling for coupling the housing with the third port of the valve mechanism such that the housing is in fluid communication with the valve mechanism.</claim-text> <claim-text>6. An apparatus according to claim 5 when appended to claim 4. wherein the coupling engages with said mechanical switch such that when the housing is coupled with the third port the valve mechanism is in state a) and when the housing is uncoupled from the third port the valve mechanism is in state b).</claim-text> <claim-text>7. An apparatus according to claim 3, wherein the valve mechanism comprises a pair of one-way valves.</claim-text> <claim-text>8. An apparatus according to any one of the preceding claims, wherein the housing defines an insertion port through which an ampoule can be inserted into the interior space.</claim-text> <claim-text>9. An apparatus according to claim 8, wherein the insertion port comprises a one-way flap valve to inhibit the removal of the ampoule after insertion into the housing.</claim-text> <claim-text>10. An apparatus according to any one of the preceding claims, wherein the mechanism for breaking open the ampoule comprises a deformable part and a rigid part such that the rigid part supports the ampoule and when a force is applied to the ampoule by way of the deformable part, the rigid part resists movement and the ampoule is broken.</claim-text> <claim-text>11. An apparatus according to any one of the preceding claims, wherein the inside structure of the housing comprises a rigid part that supports an ampoule at its top and bottom and leaves it unsupported in the middle.</claim-text> <claim-text>12. A device for releasing fluid from an ampoule, the device comprising: a lower part of rigid material; and an upper part of deformable material; wherein the upper part and the lower part are connected so as to define an interior space, and wherein one of the upper or lower parts defines an insertion port through which an ampoule can be inserted into the interior space, and wherein the lower part is formed to support the ampoule at each end but not in the middle such that when an external force is applied to the upper part, the upper part is deformed towards the ampoule and the force is subsequently applied to the ampoule which breaks in the middle where is it unsupported.</claim-text> <claim-text>13. A device according to claim 12, wherein the device also comprises a port for coupling the device to a valve mechanism such that the interior space is in fluid communication with the valve mechanism.</claim-text> <claim-text>14. A device according to any one of claims 12 or 13, wherein the insertion port comprises a one-way flap valve to inhibit the removal of the ampoule from the device after insertion.</claim-text>
GB1103571.4A 2011-03-02 2011-03-02 An apparatus for filling a syringe Withdrawn GB2492941A (en)

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GB2492941A true GB2492941A (en) 2013-01-23

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108601889A (en) * 2016-01-27 2018-09-28 康尔福盛303公司 Intermittent infusion device
USD914208S1 (en) 2019-06-14 2021-03-23 Owen Mumford Limited Syringe component
USD938022S1 (en) 2016-08-10 2021-12-07 Owen Mumford Limited Safety pen needle
USD952136S1 (en) 2019-06-14 2022-05-17 Owen Mumford Limited Syringe
USD959651S1 (en) 2020-04-08 2022-08-02 Owen Mumford Limited Medical instrument
USD972745S1 (en) 2020-05-07 2022-12-13 Owen Mumford Limited Testing device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892237A (en) * 1973-07-17 1975-07-01 Maurice Steiner Self-injecting syringe
WO1996029113A1 (en) * 1995-03-20 1996-09-26 Medimop Medical Projects Ltd. Fluid control device
WO1999037256A1 (en) * 1998-01-21 1999-07-29 Immedica Bone cement mixer and dispenser
US20050131357A1 (en) * 2003-12-16 2005-06-16 Denton Marshall T. Vial multi-access adapter
WO2007105221A1 (en) * 2006-03-16 2007-09-20 Medimop Medical Projects Ltd Fluid transfer devices for use with cartridges
WO2008135989A1 (en) * 2007-05-02 2008-11-13 Medimop Medical Projects Ltd Automatic liquid drug preparation apparatus for the preparation of a predetermined dosage of liquid drug
WO2010145041A1 (en) * 2009-06-19 2010-12-23 Medmix Systems Ag Devices for filling a multi-use syringe or single-use syringe

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892237A (en) * 1973-07-17 1975-07-01 Maurice Steiner Self-injecting syringe
WO1996029113A1 (en) * 1995-03-20 1996-09-26 Medimop Medical Projects Ltd. Fluid control device
WO1999037256A1 (en) * 1998-01-21 1999-07-29 Immedica Bone cement mixer and dispenser
US20050131357A1 (en) * 2003-12-16 2005-06-16 Denton Marshall T. Vial multi-access adapter
WO2007105221A1 (en) * 2006-03-16 2007-09-20 Medimop Medical Projects Ltd Fluid transfer devices for use with cartridges
WO2008135989A1 (en) * 2007-05-02 2008-11-13 Medimop Medical Projects Ltd Automatic liquid drug preparation apparatus for the preparation of a predetermined dosage of liquid drug
WO2010145041A1 (en) * 2009-06-19 2010-12-23 Medmix Systems Ag Devices for filling a multi-use syringe or single-use syringe

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* Cited by examiner, † Cited by third party
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CN108601889A (en) * 2016-01-27 2018-09-28 康尔福盛303公司 Intermittent infusion device
CN108601889B (en) * 2016-01-27 2021-01-08 康尔福盛303公司 Intermittent infusion device
US11103635B2 (en) 2016-01-27 2021-08-31 Carefusion 303, Inc. Micro-infusion device and infusion set
USD938022S1 (en) 2016-08-10 2021-12-07 Owen Mumford Limited Safety pen needle
USD959654S1 (en) 2016-08-10 2022-08-02 Owen Mumford Limited Safety pen needle
USD914208S1 (en) 2019-06-14 2021-03-23 Owen Mumford Limited Syringe component
USD952136S1 (en) 2019-06-14 2022-05-17 Owen Mumford Limited Syringe
USD959651S1 (en) 2020-04-08 2022-08-02 Owen Mumford Limited Medical instrument
USD972745S1 (en) 2020-05-07 2022-12-13 Owen Mumford Limited Testing device

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