GB2490782B - Delivery system for an active substance - Google Patents
Delivery system for an active substanceInfo
- Publication number
- GB2490782B GB2490782B GB1207822.6A GB201207822A GB2490782B GB 2490782 B GB2490782 B GB 2490782B GB 201207822 A GB201207822 A GB 201207822A GB 2490782 B GB2490782 B GB 2490782B
- Authority
- GB
- United Kingdom
- Prior art keywords
- active substance
- polymer
- substrate
- delivery system
- cyclodextrin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M10/00—Physical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents, or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements
- D06M10/02—Physical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents, or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements ultrasonic or sonic; Corona discharge
- D06M10/025—Corona discharge or low temperature plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6953—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a fibre, a textile, a slab or a sheet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8123—Compositions of homopolymers or copolymers of compounds having one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers, e.g. PVC, PTFE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/16—Cyclodextrin; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D105/00—Coating compositions based on polysaccharides or on their derivatives, not provided for in groups C09D101/00 or C09D103/00
- C09D105/16—Cyclodextrin; Derivatives thereof
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M10/00—Physical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents, or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements
- D06M10/04—Physical treatment combined with treatment with chemical compounds or elements
- D06M10/08—Organic compounds
- D06M10/10—Macromolecular compounds
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/03—Polysaccharides or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/61—Surface treated
- A61K2800/62—Coated
- A61K2800/624—Coated by macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D1/00—Processes for applying liquids or other fluent materials
- B05D1/18—Processes for applying liquids or other fluent materials performed by dipping
- B05D1/185—Processes for applying liquids or other fluent materials performed by dipping applying monomolecular layers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D1/00—Processes for applying liquids or other fluent materials
- B05D1/62—Plasma-deposition of organic layers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Textile Engineering (AREA)
- Birds (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Plasma & Fusion (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Paints Or Removers (AREA)
Abstract
A delivery system for an active substance, comprises a substrate 2 on which the substance is loaded for subsequent release, wherein: (i) the substrate has been at least partially coated with a polymer 3 using plasma deposition (preferably pulsed plasma deposition); (ii) the active substance is present as a guest molecule within a cyclodextrin inclusion complex 1; and (iii) the inclusion complex is bound to the polymer through a chemical linkage to formed between a hydroxyl group on the cyclodextrin and a functionalgroup on the polymer. The system may be used to control the release of an active substance such as a perfume from a substrate such as a textile. Also provided are methods for preparing (a) the delivery system and (b) a functionalised substrate for use as part of the system, in which the polymer is suitably reacted with a cyclodextrin using an SN2 nucleophilic substitution reaction, in particular a Williamson ether synthesis reaction.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201107494A GB201107494D0 (en) | 2011-05-05 | 2011-05-05 | Product |
GBGB1112404.7A GB201112404D0 (en) | 2011-07-19 | 2011-07-19 | Method |
Publications (3)
Publication Number | Publication Date |
---|---|
GB201207822D0 GB201207822D0 (en) | 2012-06-13 |
GB2490782A GB2490782A (en) | 2012-11-14 |
GB2490782B true GB2490782B (en) | 2013-12-04 |
Family
ID=46172801
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1207822.6A Expired - Fee Related GB2490782B (en) | 2011-05-05 | 2012-05-04 | Delivery system for an active substance |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2707535A2 (en) |
CN (1) | CN103814169A (en) |
GB (1) | GB2490782B (en) |
TW (1) | TW201311965A (en) |
WO (1) | WO2012150459A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113777100B (en) * | 2021-08-27 | 2022-11-01 | 厦门大学 | Quantitative substance controlled release system and method based on host-guest action |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19849464A1 (en) * | 1997-04-30 | 2000-04-27 | Schering Ag | Stent with polymeric coating having pockets, preferably cyclodextrin stuctures, containing active agent for prophylaxis of restenosis |
US6613703B1 (en) * | 2000-04-27 | 2003-09-02 | Kimberly-Clark Worldwide, Inc. | Thermoplastic nonwoven web chemically reacted with a cyclodextrin compound |
GB0212848D0 (en) | 2002-06-01 | 2002-07-17 | Surface Innovations Ltd | Introduction of liquid/solid slurry into an exciting medium |
US20070161308A1 (en) * | 2006-01-12 | 2007-07-12 | North Carolina State University | Atmospheric pressure plasma-aided antimicrobial finishes of textiles |
US9198875B2 (en) | 2008-08-17 | 2015-12-01 | Massachusetts Institute Of Technology | Controlled delivery of bioactive agents from decomposable films |
-
2012
- 2012-05-04 EP EP12723892.1A patent/EP2707535A2/en not_active Withdrawn
- 2012-05-04 CN CN201280032861.7A patent/CN103814169A/en active Pending
- 2012-05-04 WO PCT/GB2012/050971 patent/WO2012150459A2/en active Application Filing
- 2012-05-04 TW TW101116055A patent/TW201311965A/en unknown
- 2012-05-04 GB GB1207822.6A patent/GB2490782B/en not_active Expired - Fee Related
Non-Patent Citations (3)
Title |
---|
ACS Applied Materials & Interfaces, Vol. 3 (6), 2011, Schofield, W.C.E., et al., "Controlled fragrant molecule release from surface-tethered cyclodextrin host-guest inclusion complexes", pp. 2051-2056. * |
Journal of Applied Polymer Science, Vol. 77, 2000, Le Thuaut, P., et al., "Grafting of Cyclodextrins onto Polypropylene Nonwoven Fabrics for the Manufacture of Reactive Filters. I. Synthesis Parameters", pp. 2118-2125. * |
Journal of Physical Chemistry B, Vol. 110, 2006, Schofield, W.C.E., et al., "A Substrate-Independent Approach for Cyclodextrin Functionalized Surfaces", see pp. 17161-17166. * |
Also Published As
Publication number | Publication date |
---|---|
WO2012150459A2 (en) | 2012-11-08 |
GB2490782A (en) | 2012-11-14 |
GB201207822D0 (en) | 2012-06-13 |
EP2707535A2 (en) | 2014-03-19 |
TW201311965A (en) | 2013-03-16 |
CN103814169A (en) | 2014-05-21 |
WO2012150459A3 (en) | 2013-01-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Feghali et al. | Unprecedented organocatalytic reduction of lignin model compounds to phenols and primary alcohols using hydrosilanes | |
MX363512B (en) | Glycoconjugation process. | |
MX340962B (en) | Cannabinoid receptor binding agents, compositions and methods. | |
MY181013A (en) | Polymer conjugate for delivery of a bioactive agent | |
WO2012110636A3 (en) | Carrier peptides for cell delivery | |
DE502008003182D1 (en) | ODUCTION BLADE OF RING-SHAPED SHELL CATALYSTS IN A REAGENT TUBE OF A TUBE BREAKER | |
MX361102B (en) | Shaping keratin fibres using an active agent comprising at least two functional groups selected from: -c(oh)- and -c(=o)oh. | |
BR112013023578A2 (en) | zinc-imidazole carboxylate-complexed coating material composition | |
MX2012000379A (en) | Process for the manufacture of halogenated precursors of alkenones in the presence of a solvent. | |
AR066572A1 (en) | A REACTOR SYSTEM AND A PROCESS FOR THE REACTION OF A SOURCE | |
WO2008009831A3 (en) | Novel amphiphilic cyclodextrin derivatives | |
MX338828B (en) | Masterbatch and process for preparing a polymer composition. | |
WO2010122246A3 (en) | Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions | |
MY161943A (en) | Composition for pest conrol aerosol | |
BR112013028639A2 (en) | lining composition, pipe, process for lining a pipe | |
MX339300B (en) | Small molecule inhibitors of n-terminus activation of the androgen receptor. | |
PH12019550230A1 (en) | Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation | |
WO2014079745A3 (en) | Benefit delivery particle, compositions comprising said particles and a method for treating substrates | |
GB2490782B (en) | Delivery system for an active substance | |
WO2011086412A3 (en) | Imidazolone-chalcone derivatives as potential anticancer agent and process for the preparation thereof | |
MX2015008564A (en) | A composition, articles made therefrom, and method of making the articles. | |
MY162168A (en) | Single-chamber vaporizer and use thereof in chemical synthesis | |
IN2012DE02621A (en) | ||
AR089346A1 (en) | PROCEDURE FOR PREPARATION OF A MIXTURE OF ALCOHOLS | |
TR201906505T4 (en) | Bis-imine pyridine compound of lanthanides, catalytic system containing said bis-imine pyridine compound and process for (co) polymerization of conjugated dienes. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20160504 |