GB2476603B - Method of charge reduction of electron transfer dissociation product ions - Google Patents

Method of charge reduction of electron transfer dissociation product ions

Info

Publication number
GB2476603B
GB2476603B GB1105760.1A GB201105760A GB2476603B GB 2476603 B GB2476603 B GB 2476603B GB 201105760 A GB201105760 A GB 201105760A GB 2476603 B GB2476603 B GB 2476603B
Authority
GB
United Kingdom
Prior art keywords
electron transfer
product ions
transfer dissociation
charge reduction
dissociation product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1105760.1A
Other versions
GB2476603A (en
GB201105760D0 (en
Inventor
Weibin Chen
Asish B Chakraborty
John Charles Gebler
Jeffery Mark Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0820308.5A external-priority patent/GB0820308D0/en
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority claimed from GB1012803.1A external-priority patent/GB2470133B/en
Publication of GB201105760D0 publication Critical patent/GB201105760D0/en
Publication of GB2476603A publication Critical patent/GB2476603A/en
Application granted granted Critical
Publication of GB2476603B publication Critical patent/GB2476603B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0072—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by ion/ion reaction, e.g. electron transfer dissociation, proton transfer dissociation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0077—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction specific reactions other than fragmentation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/065—Ion guides having stacked electrodes, e.g. ring stack, plate stack

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1105760.1A 2008-06-05 2009-06-05 Method of charge reduction of electron transfer dissociation product ions Active GB2476603B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5919908P 2008-06-05 2008-06-05
GBGB0820308.5A GB0820308D0 (en) 2008-11-06 2008-11-06 Mass spectrometer
GB1012803.1A GB2470133B (en) 2008-06-05 2009-06-05 Method of charge reduction of electron transfer dissociation product ions

Publications (3)

Publication Number Publication Date
GB201105760D0 GB201105760D0 (en) 2011-05-18
GB2476603A GB2476603A (en) 2011-06-29
GB2476603B true GB2476603B (en) 2013-01-09

Family

ID=44144673

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1105760.1A Active GB2476603B (en) 2008-06-05 2009-06-05 Method of charge reduction of electron transfer dissociation product ions

Country Status (1)

Country Link
GB (1) GB2476603B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201019337D0 (en) * 2010-11-16 2010-12-29 Micromass Ltd Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis
WO2013072565A1 (en) * 2011-11-15 2013-05-23 University Of Helsinki Method and device for determining properties of gas phase bases or acids
WO2016011355A1 (en) 2014-07-18 2016-01-21 Thermo Finnigan Llc Methods for mass spectrometry of mixtures of proteins of polypeptides using proton transfer reaction
EP3193352A1 (en) 2016-01-14 2017-07-19 Thermo Finnigan LLC Methods for mass spectrometric based characterization of biological molecules
GB202013553D0 (en) 2020-08-28 2020-10-14 Ancon Tech Limited A method and apparatus for interfacing ion and molecular selecting devices with an ion counter

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020166958A1 (en) * 2001-04-23 2002-11-14 Afeyan Noubar B. Tailored waveform/charge reduction mass spectrometry
WO2006103412A2 (en) * 2005-03-29 2006-10-05 Thermo Finnigan Llc Improvements relating to mass spectrometry
US20060255261A1 (en) * 2005-04-04 2006-11-16 Craig Whitehouse Atmospheric pressure ion source for mass spectrometry
GB2455191A (en) * 2007-11-23 2009-06-03 Micromass Ltd A travelling wave ion tunnel reaction/fragmentation cell

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020166958A1 (en) * 2001-04-23 2002-11-14 Afeyan Noubar B. Tailored waveform/charge reduction mass spectrometry
WO2006103412A2 (en) * 2005-03-29 2006-10-05 Thermo Finnigan Llc Improvements relating to mass spectrometry
US20060255261A1 (en) * 2005-04-04 2006-11-16 Craig Whitehouse Atmospheric pressure ion source for mass spectrometry
GB2455191A (en) * 2007-11-23 2009-06-03 Micromass Ltd A travelling wave ion tunnel reaction/fragmentation cell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of the American Society for Mass Spectrometry Vol. 19, No. 4, 17 January 2008, pages 455-466 *

Also Published As

Publication number Publication date
GB2476603A (en) 2011-06-29
GB201105760D0 (en) 2011-05-18

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