GB2474163A - Improvements in reactor apparatus - Google Patents

Improvements in reactor apparatus Download PDF

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Publication number
GB2474163A
GB2474163A GB1100525A GB201100525A GB2474163A GB 2474163 A GB2474163 A GB 2474163A GB 1100525 A GB1100525 A GB 1100525A GB 201100525 A GB201100525 A GB 201100525A GB 2474163 A GB2474163 A GB 2474163A
Authority
GB
United Kingdom
Prior art keywords
heating element
hrm
heating
insulative material
thermally insulative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1100525A
Other versions
GB201100525D0 (en
GB2474163B (en
Inventor
David Ward
Nelson Nazareth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOGENE Ltd
BG Research Ltd
Original Assignee
BIOGENE Ltd
BG Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOGENE Ltd, BG Research Ltd filed Critical BIOGENE Ltd
Publication of GB201100525D0 publication Critical patent/GB201100525D0/en
Publication of GB2474163A publication Critical patent/GB2474163A/en
Application granted granted Critical
Publication of GB2474163B publication Critical patent/GB2474163B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1883—Means for temperature control using thermal insulation

Abstract

Apparatus for effecting a chemical or biological reaction comprising: a heat removal module comprising a thermally conductive material having therein a channel adapted for the flow of a coolant liquid, a heating element mounted upon the HRM; and a layer of thermally insulative material between the HRM and the heater, the thermally insulative material having the property of restricting heat loss from the heating element into the HRM while the heating element is in heating mode while permitting heat transfer therethrough when the heating element is not in heating mode.
GB1100525.3A 2008-07-24 2009-07-23 Improvements in reactor apparatus Expired - Fee Related GB2474163B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0813562A GB0813562D0 (en) 2008-07-24 2008-07-24 Improvements in reactor apparatus
PCT/GB2009/001838 WO2010010361A1 (en) 2008-07-24 2009-07-23 Improvements in reactor apparatus

Publications (3)

Publication Number Publication Date
GB201100525D0 GB201100525D0 (en) 2011-03-02
GB2474163A true GB2474163A (en) 2011-04-06
GB2474163B GB2474163B (en) 2013-04-10

Family

ID=39746868

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0813562A Ceased GB0813562D0 (en) 2008-07-24 2008-07-24 Improvements in reactor apparatus
GB1100525.3A Expired - Fee Related GB2474163B (en) 2008-07-24 2009-07-23 Improvements in reactor apparatus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0813562A Ceased GB0813562D0 (en) 2008-07-24 2008-07-24 Improvements in reactor apparatus

Country Status (2)

Country Link
GB (2) GB0813562D0 (en)
WO (1) WO2010010361A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012063011A2 (en) * 2010-11-08 2012-05-18 Bg Research Ltd Heating and cooling low volume biological reaction vessels

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939312A (en) * 1995-05-24 1999-08-17 Biometra Biomedizinische Analytik Gmbh Miniaturized multi-chamber thermocycler
WO2001008800A1 (en) * 1999-07-30 2001-02-08 Bio-Rad Laboratories, Inc. Temperature control for multi-vessel reaction apparatus
US20020155036A1 (en) * 1998-08-13 2002-10-24 Symyx Technologies, Inc. Multi-temperature modular reactor and method of using same
US6572828B1 (en) * 1999-07-16 2003-06-03 General Electric Company Method and apparatus for high-throughput chemical screening
WO2007138302A1 (en) * 2006-05-26 2007-12-06 Bg Research Ltd Performance issues in use of vessels for biological applications
US20070295705A1 (en) * 2004-05-24 2007-12-27 Andreas Geisbauer Tempering Methods and Tempering Device for the Thermal Treatment of Small Amounts of Liquid
EP1878502A1 (en) * 2006-07-14 2008-01-16 Roche Diagnostics GmbH Instrument for heating and cooling
US20080064086A1 (en) * 2006-09-13 2008-03-13 Electronics And Telecommunications Research Institute Plastic-based microfabricated thermal device, manufacturing method thereof, dna amplification chip using the plastic-based microfabricated thermal device, and method for manufacturing the dna amplification chip
WO2008107683A2 (en) * 2007-03-08 2008-09-12 Bg Research Ltd Thermal cycling apparatus and process

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939312A (en) * 1995-05-24 1999-08-17 Biometra Biomedizinische Analytik Gmbh Miniaturized multi-chamber thermocycler
US20020155036A1 (en) * 1998-08-13 2002-10-24 Symyx Technologies, Inc. Multi-temperature modular reactor and method of using same
US6572828B1 (en) * 1999-07-16 2003-06-03 General Electric Company Method and apparatus for high-throughput chemical screening
WO2001008800A1 (en) * 1999-07-30 2001-02-08 Bio-Rad Laboratories, Inc. Temperature control for multi-vessel reaction apparatus
US20070295705A1 (en) * 2004-05-24 2007-12-27 Andreas Geisbauer Tempering Methods and Tempering Device for the Thermal Treatment of Small Amounts of Liquid
WO2007138302A1 (en) * 2006-05-26 2007-12-06 Bg Research Ltd Performance issues in use of vessels for biological applications
EP1878502A1 (en) * 2006-07-14 2008-01-16 Roche Diagnostics GmbH Instrument for heating and cooling
US20080064086A1 (en) * 2006-09-13 2008-03-13 Electronics And Telecommunications Research Institute Plastic-based microfabricated thermal device, manufacturing method thereof, dna amplification chip using the plastic-based microfabricated thermal device, and method for manufacturing the dna amplification chip
WO2008107683A2 (en) * 2007-03-08 2008-09-12 Bg Research Ltd Thermal cycling apparatus and process

Also Published As

Publication number Publication date
GB201100525D0 (en) 2011-03-02
GB2474163B (en) 2013-04-10
GB0813562D0 (en) 2008-09-03
WO2010010361A1 (en) 2010-01-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20180723