GB2459953B - Fragmentation of analyte ions in RF ion traps - Google Patents

Fragmentation of analyte ions in RF ion traps

Info

Publication number
GB2459953B
GB2459953B GB0907340.4A GB0907340A GB2459953B GB 2459953 B GB2459953 B GB 2459953B GB 0907340 A GB0907340 A GB 0907340A GB 2459953 B GB2459953 B GB 2459953B
Authority
GB
United Kingdom
Prior art keywords
fragmentation
analyte ions
ion traps
traps
ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0907340.4A
Other versions
GB2459953A (en
GB0907340D0 (en
Inventor
Andreas Brekenfeld
Ralf Hartmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Daltonics GmbH and Co KG
Original Assignee
Bruker Daltonik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102008023694A external-priority patent/DE102008023694B4/en
Application filed by Bruker Daltonik GmbH filed Critical Bruker Daltonik GmbH
Priority to GB0907340.4A priority Critical patent/GB2459953B/en
Publication of GB0907340D0 publication Critical patent/GB0907340D0/en
Publication of GB2459953A publication Critical patent/GB2459953A/en
Application granted granted Critical
Publication of GB2459953B publication Critical patent/GB2459953B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0072—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by ion/ion reaction, e.g. electron transfer dissociation, proton transfer dissociation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB0907340.4A 2008-05-15 2009-04-29 Fragmentation of analyte ions in RF ion traps Active GB2459953B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0907340.4A GB2459953B (en) 2008-05-15 2009-04-29 Fragmentation of analyte ions in RF ion traps

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008023694A DE102008023694B4 (en) 2008-05-15 2008-05-15 Fragmentation of analyte ions by ion impact in RF ion traps
GB0907340.4A GB2459953B (en) 2008-05-15 2009-04-29 Fragmentation of analyte ions in RF ion traps

Publications (3)

Publication Number Publication Date
GB0907340D0 GB0907340D0 (en) 2009-06-10
GB2459953A GB2459953A (en) 2009-11-18
GB2459953B true GB2459953B (en) 2012-03-21

Family

ID=40791968

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0907340.4A Active GB2459953B (en) 2008-05-15 2009-04-29 Fragmentation of analyte ions in RF ion traps

Country Status (1)

Country Link
GB (1) GB2459953B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2511035B (en) * 2013-02-14 2018-10-24 Thermo Fisher Scient Bremen Gmbh Ion fragmentation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128542A (en) * 1991-01-25 1992-07-07 Finnigan Corporation Method of operating an ion trap mass spectrometer to determine the resonant frequency of trapped ions
US6124591A (en) * 1998-10-16 2000-09-26 Finnigan Corporation Method of ion fragmentation in a quadrupole ion trap
US20060054808A1 (en) * 2004-09-14 2006-03-16 Schwartz Jae C High-Q pulsed fragmentation in ion traps
GB2446249A (en) * 2006-12-04 2008-08-06 Bruker Daltonik Gmbh Collision induced decomposition of ions in RF ion traps
US20090050798A1 (en) * 2005-06-03 2009-02-26 Ohio University Method for Sequencing Peptides and Proteins Using Metastable-Activated Dissociation Mass Spectrometry

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128542A (en) * 1991-01-25 1992-07-07 Finnigan Corporation Method of operating an ion trap mass spectrometer to determine the resonant frequency of trapped ions
US6124591A (en) * 1998-10-16 2000-09-26 Finnigan Corporation Method of ion fragmentation in a quadrupole ion trap
US20060054808A1 (en) * 2004-09-14 2006-03-16 Schwartz Jae C High-Q pulsed fragmentation in ion traps
US20090050798A1 (en) * 2005-06-03 2009-02-26 Ohio University Method for Sequencing Peptides and Proteins Using Metastable-Activated Dissociation Mass Spectrometry
GB2446249A (en) * 2006-12-04 2008-08-06 Bruker Daltonik Gmbh Collision induced decomposition of ions in RF ion traps

Also Published As

Publication number Publication date
GB2459953A (en) 2009-11-18
GB0907340D0 (en) 2009-06-10

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Legal Events

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732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20210722 AND 20210728