GB2449449A - Spacer allowing use of different size cartridges in a syringe - Google Patents
Spacer allowing use of different size cartridges in a syringe Download PDFInfo
- Publication number
- GB2449449A GB2449449A GB0709772A GB0709772A GB2449449A GB 2449449 A GB2449449 A GB 2449449A GB 0709772 A GB0709772 A GB 0709772A GB 0709772 A GB0709772 A GB 0709772A GB 2449449 A GB2449449 A GB 2449449A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cartridge
- chamber
- plunger
- administering
- hypodermic injection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 125000006850 spacer group Chemical group 0.000 title 1
- 238000002347 injection Methods 0.000 claims abstract description 25
- 239000007924 injection Substances 0.000 claims abstract description 25
- 238000012856 packing Methods 0.000 claims abstract description 19
- 230000004323 axial length Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 230000003444 anaesthetic effect Effects 0.000 abstract description 6
- 230000000994 depressogenic effect Effects 0.000 abstract description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 8
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 210000004204 blood vessel Anatomy 0.000 description 5
- 229960005015 local anesthetics Drugs 0.000 description 4
- 229940124326 anaesthetic agent Drugs 0.000 description 3
- 239000003193 general anesthetic agent Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- 238000001949 anaesthesia Methods 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 1
- 108010003272 Hyaluronate lyase Proteins 0.000 description 1
- 102000001974 Hyaluronidases Human genes 0.000 description 1
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical class NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229960002773 hyaluronidase Drugs 0.000 description 1
- XPXMKIXDFWLRAA-UHFFFAOYSA-N hydrazinide Chemical compound [NH-]N XPXMKIXDFWLRAA-UHFFFAOYSA-N 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229960002409 mepivacaine Drugs 0.000 description 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 229960002748 norepinephrine Drugs 0.000 description 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 229960001807 prilocaine Drugs 0.000 description 1
- MVFGUOIZUNYYSO-UHFFFAOYSA-N prilocaine Chemical compound CCCNC(C)C(=O)NC1=CC=CC=C1C MVFGUOIZUNYYSO-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960002372 tetracaine Drugs 0.000 description 1
- GKCBAIGFKIBETG-UHFFFAOYSA-N tetracaine Chemical compound CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 GKCBAIGFKIBETG-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000005526 vasoconstrictor agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2433—Ampoule fixed to ampoule holder
- A61M2005/2437—Ampoule fixed to ampoule holder by clamping means
- A61M2005/244—Ampoule fixed to ampoule holder by clamping means by flexible clip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3148—Means for causing or aiding aspiration or plunger retraction
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Apparatus for injecting dental local anaesthetic comprises a chamber 18 holding a cartridge 26 containing 1.8ml of anaesthetic. To make an injection, a plunger 22 attached to a slidable bung 28 of the cartridge 26 is depressed in the direction of arrow A to deliver the anaesthetic by way of a needle 20 having a tail 20 perforating a septum 12 at the forward end of the cartridge 26. The chamber 18 is configured and arranged to hold a standard (2.2ml) cartridge as a snug fit therein but a tubular packing piece 24 allows it to accommodate the 1.8ml cartridge 26. Aspiration can be carried out before the injection is administered, by slightly retracting the plunger 22, and different sizes of packing pieces may be used in association with different sized cartridges.
Description
-1-2449449
HYPODERMIC INJECTION APPARATUS
This invention concerns apparatus for administering hypodermic injections particularly but not necessarily exclusively of dental local anaesthetics.
Dental surgeons throughout the world commonly use a cartridge type of hypodermic injection apparatus to administer local anaesthetics. This type of apparatus has a reusable actuating mechanism formed with a chamber into which is loaded a tubular cartridge containing local anaesthetic agent -typically an amino-ester or an amino-amide mixed with a proportion of adrenaline. The cartridge is closed at its forward end with a septum and at its rearward end has a slideable bung arranged to be engaged by a plunger of the actuating mechanism when the cartridge is in the chamber. After the cartridge has been loaded into the chamber a needle is attached to its forward end, usually by means of a screw thread arrangement, and a rearwardily extending tail of the needle perforates the septum.
Then the practitioner can depress the plunger to drive the bung axially forwards into the cartridge and expel the contents thereof to make an injection in the usual way.
Whilst this type of hypodermic injection apparatus is in almost universal use by dentists, there are various differences of detail, of which the most significant in relation to the present invention is the volume of the cartridge. In the United Kingdom and certain other countries, for instance, dentists use a cartridge containing 2.2m1 of anaesthetic agent, whereas in Germany a I.8m1 cartridge is general, sometimes a I.7m1 cartridge is used, and in Japan and some Pacific Rim countries the cartridge may be as small as 1.Oml. All these cartridges are of substantially the same diameter, the volume being adjusted by varying the length of the cartridge. Thus the 1.8m1 cartridge is 15mm shorter than the 2.2m1 cartridge (which latter will hereinafter be referred to as a "standard" cartridge).
The dimensions of the actuating mechanism vary similarly. Thus a standard cartridge is a snug fit in the chamber of an actuating mechanism designed for it, but the other cartridges, being shorter, do not fill the length of the chamber. The shortage in length gives rise to problems with aspiration, as will now be described.
As will be well known to those skilled in dentistry, aspiration is a pre-administration procedure whereby a dental practitioner checks the position of the needle tip relative to blood vessels in a patient's mouth. This is done for reasons of patient safety, to ensure that the local anaesthetic agent is not injected into the circulatory system. Intravascular injection gives rise to the risk of a toxic reaction, especially if administered quickly, when the injectant may travel around the body as a bolus to arrive at the brain in abnormally high concentration. This may happen with any injectant but is notably serious in the case of local anaesthesia, especially if the anaesthetic agent is combined with adrenaline, since adrenaline entering the circulation system may have fatal consequences. The danger is particularly severe in dental local anaesthesia because the injection site is so close to the patient's brain.
In aspiration, after the needle has been inserted into the injection site, the plunger of the syringe is retracted by a small amount to obtain a sample of the surrounding body material. If the tip of the needle is in a blood vessel, a sample of blood will be drawn back into the syringe where it can be observed, and if blood is seen, the practitioner can begin again, altering the position of the needle.
In one common form of injection apparatus for use with a standard cartridge, the plunger is attached to the cartridge bung by means of a hook or screw so that when the plunger is retracted it pulls the bung back to effect aspiration. However, if this apparatus is loaded with a 1.8m1 or other smaller cartridge, retraction of the plunger pulls the whole cartridge rearwards and off the perforating tail of the needle. In these circumstances, no blood appears in the cartridge, regardless of the position of the needle, and if the plunger is pushed forward again to continue the injection the cartridge is pushed back onto the needle tail and the injectant administered, possibly into a blood vessel because of the false aspiration.
Another common form of injection apparatus (sometimes known as a "thumb-ring" or "rotor" syringe) for use with a standard cartridge has an elastic diaphragm for aspiration. Forward pressure on the plunger first moves the cartridge bodily forwards so that the diaphragm is deformed inwardly of the cartridge by a nipple formed on the syringe. If the pressure is then released, the diaphragm resiles to effect aspiration. But if a smaller cartridge is used in a such apparatus designed for a standard cartridge, its diaphragm is not deformed, so there is no aspiration.
For efficient manufacture and supply, it is desirable to be able to deliver smaller cartridges to territories where standard cartridges are the norm, and therefore it is an object of the present invention to provide for effective aspiration when such smaller cartridges are used in injection apparatus designed for a standard cartridge.
Thus according to the invention there is provided apparatus for administering a hypodermic injection, which apparatus includes an axially extending chamber to receive a tubular cartridge wherein injectant is contained by a slidable bung, a plunger axially movable and in use engageable with said bung to slide it, and means responsive to movement of the plunger in use to effect aspiration, wherein said apparatus includes a packing element to fit the cartridge to the chamber.
The invention is particularly intended to enable the use of cartridges shorter than the chamber, to which end in use the packing element preferably fills the shortage therebetween. The packing element may comprise a tube of substantially the same diameter as the cartridge and of length substantially equal to the difference between the axial length of the chamber and the axial length of the cartridge.
The plunger may extend through said packing element to engage said bung.
Apparatus according to the invention may include a plurality of packing elements variously configured and arranged to fit cartridges of various dimensions to the chamber.
Other features of the invention will be apparent from the following description, which is made by way of example only and with reference to the accompanying schematic drawing in which -Figure 1 shows in side elevation apparatus for administering a hypodermic injection of dental local anaesthetic by means of a 2.2m1 cartridge and Figure 2 shows the apparatus of Figure 1 arranged for administering a hypodermic injection by means of a 1.8m1 cartridge.
Referring first to Figure 1, this shows a tubular glass cartridge 10 containing 2.2m1 of dental local anaesthetic. For simplicity the anaesthetic agent within the cartridge 10 is not shown in the drawing, but it may be any of a range of agents such as amino-esters (eg procaine or tetracaine) or amino-amides (eg lidocaine, prilocaine or mepivacaine) typically with the addition of a vasoconstrictor such as adrenaline or noradrenaline, a preservative such as methylparaben and/or a spreading agent such as hyaluronidase.. The cartridge 10 is closed at one, forward, end by a rubber septum 12 held in place by an aluminium cap 14. The rear end of the cartridge 10 is closed by a slidable bung 16, the periphery of which sealingly engages the inner wall of the cartridge 10 to retain the anaesthetic therein.
The cartridge 10 fits snugly in a chamber 18 of an actuating mechanism. A needle 20 extends forward of the actuating mechanism (being secured thereto by means such as a Luer lock, not detailed) and has a rearwardly extending tail 20a perforating the septum 12. At the rearward end of the actuating mechanism a plunger 22 is arranged for axial movement and is attached to the bung 16 by a screw connection. (For simplicity of illustration, this screw connection is not detailed in the drawing, and it may be replaced by some othe connection such as a hook or the plunger may freely engage the bung 16).
To make an injection using the apparatus of Figure 1, the tip 20b of the needle 20 is inserted hypodermically into an injection site and the plunger 22 is depressed in the direction of arrow A to slide the bung 16 into the cartridge 10 to deliver the injectant. Before this is done, however, it is necessary to carry out an aspiration procedure to check that the needle tip 20b is not in a blood vessel. This is done by retracting the plunger 22 very slightly, withdrawing the bung 16 with it, so that if the needle tip is in a blood vessel blood will be drawn into the cartridge 10, where it can be seen. If aspiration shows blood in the cartridge 10, the needle lip 20b can be repositioned (and checked again by further aspiration).
This procedure is satisfactory provided the cartridge 10 is a snug fit in the chamber 18. However, a cartridge say of I.8m1 which substantially shorter than the chamber 18 would be pulled off the needle tail 20a when the plunger 22 is retracted, and the absence of blood appearing in the cartridge would then be a false indication of the location of the needle tip 20b. By means of the invention this is overcome, as shown in Figure 2, by means of a tubular packing element 24, separate from the chamber 18, between the rearward end of the I.8m1 cartridge 26 and the corresponding end of the chamber 18. The 1.8m1 cartridge 26 of Figure 2 is 15mm shorter than the 2.2m1 cartridge 10 of Figure 1, and accordingly the packing element 24 needs to be 15mm long to fit the 1.8m1 cartridge 26 to the chamber 18.
As can be seen from Figure 2, the packing element 24 extends through the packing element 24 and is attached to the slidable bung 28, and thus aspiration can be satisfactorily performed by the apparatus of Figure 2 even though the I.8m1 cartridge 26 is shorter than the chamber 18. It will also be noted that the packing element 24 is of substantially the same diameter as the cartridge 26, the alignment of which is thereby maintained in use.
The packing element, which may be made very inexpensively of synthetic plastics material, facilitates other kinds of aspiration such as that effected by means of a resiliently deformable membrane. Those skilled in the art will also appreciate that practitioners may be provided with packing elements of various sizes for use with cartridges of various volumes.
Claims (6)
- I Apparatus for administering a hypodermic injection, which apparatus includes an axially extending chamber to receive a tubular cartridge wherein injectant is contained by a slidable bung, a plunger axially movable and in use engageable with said bung to slide it, and means responsive to movement of the plunger in use to effect aspiration, wherein said apparatus includes a packing element to fit the cartridge to the chamber.
- 2 Apparatus for administering a hypodermic injection as claimed in Claim I wherein the cartridge is axially shorter than the chamber, and in use the packing element flils the shortage therebetween.
- 3 Apparatus for administering a hypodermic injection as claimed in Claim I or Claim 2 wherein in use the plunger extends through said packing element to engage said bung.
- 4 Apparatus for administering a hypodermic injection as claimed in any preceding claim wherein said packing element comprises a tube of substantially the same diameter as the cartridge and of length substantially equal to the difference between the axial length of the chamber and the axial length of the cartridge.
- Apparatus for administering a hypodermic injection as claimed in any preceding ciaim including a plurality of packing elements variously configured and arranged to fit cartridges of various dimensions to the chamber.
- 6 Apparatus for administering a hypodermic injection substantially as hereinbefore described with reference to and as shown in the accompanying drawing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0709772A GB2449449A (en) | 2007-05-21 | 2007-05-21 | Spacer allowing use of different size cartridges in a syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0709772A GB2449449A (en) | 2007-05-21 | 2007-05-21 | Spacer allowing use of different size cartridges in a syringe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB0709772D0 GB0709772D0 (en) | 2007-06-27 |
| GB2449449A true GB2449449A (en) | 2008-11-26 |
Family
ID=38234845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0709772A Withdrawn GB2449449A (en) | 2007-05-21 | 2007-05-21 | Spacer allowing use of different size cartridges in a syringe |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2449449A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1528735A (en) * | 1976-05-14 | 1978-10-18 | Philips Nv | Injection devices |
| EP0224362A2 (en) * | 1985-11-18 | 1987-06-03 | Mallinckrodt, Inc. (a Delaware corporation) | Power syringe with volume reducing adapter |
| JP2000102607A (en) * | 1998-09-28 | 2000-04-11 | Showa Yakuhin Kako Kk | Dental cartridge syringe |
-
2007
- 2007-05-21 GB GB0709772A patent/GB2449449A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1528735A (en) * | 1976-05-14 | 1978-10-18 | Philips Nv | Injection devices |
| EP0224362A2 (en) * | 1985-11-18 | 1987-06-03 | Mallinckrodt, Inc. (a Delaware corporation) | Power syringe with volume reducing adapter |
| JP2000102607A (en) * | 1998-09-28 | 2000-04-11 | Showa Yakuhin Kako Kk | Dental cartridge syringe |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0709772D0 (en) | 2007-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |