GB2443110A - Instruments for measuring nanoparticle exposure - Google Patents

Instruments for measuring nanoparticle exposure

Info

Publication number
GB2443110A
GB2443110A GB0725151A GB0725151A GB2443110A GB 2443110 A GB2443110 A GB 2443110A GB 0725151 A GB0725151 A GB 0725151A GB 0725151 A GB0725151 A GB 0725151A GB 2443110 A GB2443110 A GB 2443110A
Authority
GB
United Kingdom
Prior art keywords
aerosol
ions
instrument
corona discharge
charged particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0725151A
Other versions
GB0725151D0 (en
Inventor
Heinz Fissan
Andreas Trampe
David Y H Pui
Stanley L Kaufman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TSI Inc
Original Assignee
TSI Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TSI Inc filed Critical TSI Inc
Priority claimed from PCT/US2006/020071 external-priority patent/WO2006127803A2/en
Publication of GB0725151D0 publication Critical patent/GB0725151D0/en
Publication of GB2443110A publication Critical patent/GB2443110A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

An instrument for non-invasively measuring nanoparticle exposure includes a corona discharge element generating ions to effect unipolar diffusion charging of an aerosol, followed by an ion trap for removing excess ions and a portion of the charged particles with electrical mobilities above a threshold. Downstream, an electrically conductive HEPA filter or other collecting element accumulates the charged particles and provides the resultant current to an electrometer amplifier. The instrument is tunable to alter the electrometer amplifier output toward closer correspondence with a selected function describing particle behavior, e.g. nanoparticle deposition in a selected region of the respiratory system. Tuning entails adjusting voltages applied to one or more of the ion trap, the corona discharge element and the collecting element. Alternatively, tuning involves adjusting the aerosol flow rate, either directly or in comparison to the flowrate of a gas conducting the ions toward merger with the aerosol.
GB0725151A 2005-05-23 2006-05-23 Instruments for measuring nanoparticle exposure Withdrawn GB2443110A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68361505P 2005-05-23 2005-05-23
US7635506A 2006-01-31 2006-01-31
PCT/US2006/020071 WO2006127803A2 (en) 2005-05-23 2006-05-23 Instruments for measuring nanoparticle exposure

Publications (2)

Publication Number Publication Date
GB0725151D0 GB0725151D0 (en) 2008-01-30
GB2443110A true GB2443110A (en) 2008-04-23

Family

ID=39048694

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0725151A Withdrawn GB2443110A (en) 2005-05-23 2006-05-23 Instruments for measuring nanoparticle exposure

Country Status (1)

Country Link
GB (1) GB2443110A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11686660B2 (en) 2018-06-07 2023-06-27 Sensors, Inc. Particle concentration analyzing system and method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3114877A (en) * 1956-10-30 1963-12-17 Gen Electric Particle detector having improved unipolar charging structure
US5026994A (en) * 1990-08-06 1991-06-25 Rad-X Ltd. Method and apparatus for measuring the size distribution of particles
US5352892A (en) * 1992-05-29 1994-10-04 Cornell Research Foundation, Inc. Atmospheric pressure ion interface for a mass analyzer
US5973904A (en) * 1997-10-10 1999-10-26 Regents Of The University Of Minnesota Particle charging apparatus and method of charging particles
US6003389A (en) * 1996-09-05 1999-12-21 California Institute Of Technology Enhanced automated classified aerosol detector
US6568245B2 (en) * 2001-03-15 2003-05-27 Tsi Incorporated Evaporative electrical detector

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3114877A (en) * 1956-10-30 1963-12-17 Gen Electric Particle detector having improved unipolar charging structure
US5026994A (en) * 1990-08-06 1991-06-25 Rad-X Ltd. Method and apparatus for measuring the size distribution of particles
US5352892A (en) * 1992-05-29 1994-10-04 Cornell Research Foundation, Inc. Atmospheric pressure ion interface for a mass analyzer
US6003389A (en) * 1996-09-05 1999-12-21 California Institute Of Technology Enhanced automated classified aerosol detector
US5973904A (en) * 1997-10-10 1999-10-26 Regents Of The University Of Minnesota Particle charging apparatus and method of charging particles
US6568245B2 (en) * 2001-03-15 2003-05-27 Tsi Incorporated Evaporative electrical detector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11686660B2 (en) 2018-06-07 2023-06-27 Sensors, Inc. Particle concentration analyzing system and method

Also Published As

Publication number Publication date
GB0725151D0 (en) 2008-01-30

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)