GB2441600A - A purified arabinogalactan-protein (AGP) composition. - Google Patents
A purified arabinogalactan-protein (AGP) composition.Info
- Publication number
- GB2441600A GB2441600A GB0704734A GB0704734A GB2441600A GB 2441600 A GB2441600 A GB 2441600A GB 0704734 A GB0704734 A GB 0704734A GB 0704734 A GB0704734 A GB 0704734A GB 2441600 A GB2441600 A GB 2441600A
- Authority
- GB
- United Kingdom
- Prior art keywords
- protein
- agp
- inhibition
- composition
- purified arabinogalactan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108010054251 arabinogalactan proteins Proteins 0.000 title abstract 6
- 230000005764 inhibitory process Effects 0.000 abstract 4
- 240000000058 Argemone mexicana Species 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 206010014025 Ear swelling Diseases 0.000 abstract 1
- 206010062016 Immunosuppression Diseases 0.000 abstract 1
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000001530 keratinolytic effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A purified Arabinogalactan-Protein (AGP) composition isolated through a selective method from the leaves and/or stems of Argemone mexicana plant is described. Also described is a purified Arabinogalactan-Protein (AGP composition isolated from the leaves and/or stems of Argemone mexicana plant, which has one or more of the following effects: immunosuppression, lymphoproliferation inhibition, cytokine modulation such as IL-2 inhibition, IFN- q inhibition, or IL-10 induction; keratinocyte proliferation inhibition, keratolytic activity and inhibitory activity in louse Ear Swelling test (MEST).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/931,814 US7601368B2 (en) | 2004-09-01 | 2004-09-01 | Purified Arabinogalactan-Protein (AGP) composition useful in the treatment psoriasis and other disorders |
PCT/IN2005/000132 WO2006025068A1 (en) | 2004-09-01 | 2005-04-26 | A purified arabinogalactan-protein (agp) composition |
Publications (2)
Publication Number | Publication Date |
---|---|
GB0704734D0 GB0704734D0 (en) | 2007-04-18 |
GB2441600A true GB2441600A (en) | 2008-03-12 |
Family
ID=39106233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0704734A Withdrawn GB2441600A (en) | 2004-09-01 | 2007-03-12 | A purified arabinogalactan-protein (AGP) composition. |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2441600A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030194456A1 (en) * | 2002-01-10 | 2003-10-16 | Lupin Limited | Herbal composition for treating various disorders including psoriasis, a process for preparation thereof and method for treatment of such disorders |
-
2007
- 2007-03-12 GB GB0704734A patent/GB2441600A/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030194456A1 (en) * | 2002-01-10 | 2003-10-16 | Lupin Limited | Herbal composition for treating various disorders including psoriasis, a process for preparation thereof and method for treatment of such disorders |
Non-Patent Citations (2)
Title |
---|
CMLS Cellular & Molecular Life Sciences (2001); Vol 58, pp 1399-1417, "Arabinogalactan-proteins: Structure, expression and function", Showalter * |
Indian Drugs (2001); Vol 38, pp 288-293, "Preliminary phytochemical investigation...", Patil et al * |
Also Published As
Publication number | Publication date |
---|---|
GB0704734D0 (en) | 2007-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |