GB2431006A - Data capture system for microtiter plates - Google Patents
Data capture system for microtiter plates Download PDFInfo
- Publication number
- GB2431006A GB2431006A GB0518623A GB0518623A GB2431006A GB 2431006 A GB2431006 A GB 2431006A GB 0518623 A GB0518623 A GB 0518623A GB 0518623 A GB0518623 A GB 0518623A GB 2431006 A GB2431006 A GB 2431006A
- Authority
- GB
- United Kingdom
- Prior art keywords
- data recorder
- recorder according
- data
- control system
- sensor array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000013481 data capture Methods 0.000 title 1
- 230000006870 function Effects 0.000 claims description 2
- 230000003287 optical effect Effects 0.000 claims 2
- 230000001133 acceleration Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000005291 magnetic effect Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 abstract description 3
- 238000012423 maintenance Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/024—Storing results with means integrated into the container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Recording Measured Values (AREA)
Abstract
An electronic capture system, of the same size and shape as a microplate, that can be used to monitor and record the forces and environmental conditions experienced by sample microplates in automated equipment. The device may include, not exclusively; temperature sensors, humidity sensors, inertial sensors, electronic compass, ambient light level sensor, real time clock, and a triggering sub-system.
Description
DATA RECORDING MICROPLATE
DESCRIPTION
Field of invention
This invention relates to a data logger that employs an array of sensors to gather data on the forces and environmental conditions experienced by sample microplates whilst being processed by automated equipment.
Background of the invention
Microtitre plates (microplates) are routinely used to prepare, transport and store chemical and bioLogical samples. Automated systems are frequently used to perform many of the operations required to process the samples contained in micropLates but there is no accurate way of determining the environmental conditions to which the microptates are exposed when processed by such automated equipment.
Summary of the invention
To provide this information, the present invention proposes a data recording device, of the same physical dimensions as commonly available microplates, that can be handled by the same automated equipment.
The data recorder, as illustrated by Figure 1, may consist of: 1. ControLler The controller can be any embedded microprocessor or microcontroller capable of performing the following minimum functions: a. Monitoring of all sensors and peripherals to obtain contextuaL information.
b. Reacting to trigger events, reading data from the sensor array and storing it in non-voLatile memory.
c. Acting on the currently programmed configuration to determine the active trigger events and the source and sampling rate of the data to be stored.
d. Handling of interface tasks including data transfer and control, configuration and maintenance procedures.
2. Battery TypicaLly, the device will be powered by an integrated rechargable battery.
3. Sensor Array The sensor array can include, but not exclusively, temperature sensors, humidity sensors, accelerometers, ambient light level sensors, pressure sensors, electronic compass, and real time clock.
4. Tx/Rx Module The Tx/Rx Module facilitates connection of the data logger to an external system, e.g. a PC/workstation, via the base station. This enables the downloading and storing of acquired data or a continuous feed of data. It also enables device configuration and maintenance to be performed.
5. Electronic Memory This will be used to store the data retrieved from the data recorder's environment via a sensor array. It will maintain the integrity of the stored data for extended periods of time and/or during power loss until the data can be transferred to a long-term storage medium. The non-volatile memory can be implemented using EEPROM, battery backed-up SRAM or any other acceptable technology.
6. Base Station The base station wilt provide facilities for transferring stored data and configuration details between the data logger and a PC/workstation. The base station wilt also be used to recharge the battery in the data logger.
Claims (33)
1. An electronic device for capturing data pertaining to the use, storage, and transport of microplates, said device comprising: a) an array of electronic sensors; b) electronic memory to record data captured from the sensors; and c) a control system to govern the operation of the device, including the capture, storage and downloading of data.
2. A data recorder according to claim 1, in which the device is packaged to have the same external dimensions as those of a standard microtitre plate.
3. A data recorder according to claim 1, in which the device is packaged to have the same external dimensions as those of a medium well plate.
4. A data recorder according to claim 1, in which the device is packaged to have the same external dimensions as those of a deep well plate.
5. A data recorder according to claim 1, in which the sensor array includes one or more differing types of sensor.
6. A data recorder according to claim 5, in which the sensor array includes one or more of each of the following types of sensor; Temperature Sensor, Humidity Sensor, Accelerometer and Real Time Clock.
7. A data recorder according to claim 6, in which the sensor array includes one or more Pressure Sensors.
8. A data recorder according to claim 6, in which the sensor array includes an ELectronic Compass.
9. A data recorder according to claim 6, in which the sensor array includes one or more Light Level Sensors.
1O.A data recorder according to claim 6, in which the data recorder contains a subsystem to provide real time cLock information to the system.
11. A data recorder according to cLaim 6, in which the data recorder contains systems to provide information on its spatial movement and orientation.
12. A data recorder according to claim 11, in which the data recorder incorporates systems utilising gyroscopic, acceleration or magnetic effects to resolve its position and or orientation.
13.A data recorder according to claim 1, in which the data recorder incorporates solid state electronic memory to securely record data gathered by the sensor array.
14.A data recorder according to cLaim 1, in which the data recorder incorporates non volatile electronic memory to securely record data gathered by the sensor array.
15. A data recorder according to claim 1, in which the control system incorporates the ability to operate in multiple modes, allowing data to be captured and processed in manners appropriate for differing circumstances.
16.A data recorder according to claim 15, in which the operating mode of the control system can be automatically controlled by external stimuli such as temperature, humidity or light Level changes in the data recorder's immediate vicinity.
17.A data recorder according to claim 15, in which the operating mode of the control system determines the data captured from the sensor array.
18.A data recorder according to claim 15, in which the operating mode of the control system determines the data stored from the sensor array.
19. A data recorder according to claim 15, in which the operating mode of the control system determines the level of protection given to captured data when downloading to a base-station or other subsidiary device.
20. A data recorder according to claim 15, in which the operating mode of the control system allows temporarily unused functions of the device to be suspended, facilitating power conservation.
21.A data recorder according to claim 1, in which the control system incorporates the ability to interface with external systems for purposes of data transfer.
22.A data recorder according to claim 21, in which the control system incorporates the ability to interface with externaL systems for the purposes of downloading data captured from the sensor array.
23. A data recorder according to claim 21, in which the connection between the data recorder and an external system takes the form of an electrical or optical cable.
S
24.A data recorder according to claim 21, in which the connection between the data recorder and an external system utilises radio transmitters and receivers.
25. A data recorder according to cLaim 21, in which the connection between the data recorder and an external system takes the form of an optical link.
26.A data recorder according to claim 1, in which the control system incorporates the ability to interface with external systems for the purpose of reconfiguring the controL system.
27. A data recorder according to claim 1, in which the control system incorporates the ability to interface with external systems for the purpose of changing the operating mode of the data recorder.
28.A data recorder according to claim 1, in which the device is powered from an internaL power source.
29.A data recorder according to cLaim 28, in which the internal power source is recharged via an electricaL connection.
30.A data recorder according to claim 28, in which the internal power source is recharged via an inductive loop.
31. A micropLate incorporating a data recorder as claimed in any preceding claim.
32.A device for capturing data pertaining to the use, transport or storage of a microplate, substantiaLLy as hereinbefore described.
33.A micropLate incorporating a device for capturing data pertaining to the use, transport or storage of a micropLate, substantially as hereinbefore described.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0518623A GB2431006A (en) | 2005-09-12 | 2005-09-12 | Data capture system for microtiter plates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0518623A GB2431006A (en) | 2005-09-12 | 2005-09-12 | Data capture system for microtiter plates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB0518623D0 GB0518623D0 (en) | 2005-10-19 |
| GB2431006A true GB2431006A (en) | 2007-04-11 |
Family
ID=35221369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0518623A Withdrawn GB2431006A (en) | 2005-09-12 | 2005-09-12 | Data capture system for microtiter plates |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2431006A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012059701A2 (en) * | 2010-11-05 | 2012-05-10 | Cybio France Sarl | Device and method for managing microplates in an automated processing system and method for processing said microplates |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376233B1 (en) * | 1996-11-12 | 2002-04-23 | Micronas Intermetall Gmbh | Device for conducting research on cell specimens and similar materials |
| EP1284158A2 (en) * | 2001-08-07 | 2003-02-19 | Eidgenössische Technische Hochschule Zürich | Microsensor system for monitoring biological and chemical processes |
| WO2003036280A2 (en) * | 2001-10-19 | 2003-05-01 | Glaxo Group Limited | Electro thermometric method and apparatus |
| GB2404882A (en) * | 2002-11-19 | 2005-02-16 | Biogene Ltd | Microtitre plate with heating means to prevent condensation |
| WO2005105292A1 (en) * | 2004-04-30 | 2005-11-10 | Gatlik Gmbh | High throughput storage-retrieval and screening platform for research applications based on electro or acoustic sensors |
-
2005
- 2005-09-12 GB GB0518623A patent/GB2431006A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376233B1 (en) * | 1996-11-12 | 2002-04-23 | Micronas Intermetall Gmbh | Device for conducting research on cell specimens and similar materials |
| EP1284158A2 (en) * | 2001-08-07 | 2003-02-19 | Eidgenössische Technische Hochschule Zürich | Microsensor system for monitoring biological and chemical processes |
| WO2003036280A2 (en) * | 2001-10-19 | 2003-05-01 | Glaxo Group Limited | Electro thermometric method and apparatus |
| GB2404882A (en) * | 2002-11-19 | 2005-02-16 | Biogene Ltd | Microtitre plate with heating means to prevent condensation |
| WO2005105292A1 (en) * | 2004-04-30 | 2005-11-10 | Gatlik Gmbh | High throughput storage-retrieval and screening platform for research applications based on electro or acoustic sensors |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012059701A2 (en) * | 2010-11-05 | 2012-05-10 | Cybio France Sarl | Device and method for managing microplates in an automated processing system and method for processing said microplates |
| WO2012059701A3 (en) * | 2010-11-05 | 2012-07-12 | Cybio France Sarl | Device and method for managing microplates in an automated processing system and method for processing said microplates |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0518623D0 (en) | 2005-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |