GB2419462A - Ion extraction - Google Patents

Ion extraction Download PDF

Info

Publication number
GB2419462A
GB2419462A GB0600268A GB0600268A GB2419462A GB 2419462 A GB2419462 A GB 2419462A GB 0600268 A GB0600268 A GB 0600268A GB 0600268 A GB0600268 A GB 0600268A GB 2419462 A GB2419462 A GB 2419462A
Authority
GB
United Kingdom
Prior art keywords
ions
electrical field
laminar flow
ion extraction
providing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0600268A
Other versions
GB0600268D0 (en
GB2419462B (en
Inventor
John Hoyes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MS HORIZONS Ltd
Original Assignee
MS HORIZONS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MS HORIZONS Ltd filed Critical MS HORIZONS Ltd
Publication of GB0600268D0 publication Critical patent/GB0600268D0/en
Publication of GB2419462A publication Critical patent/GB2419462A/en
Application granted granted Critical
Publication of GB2419462B publication Critical patent/GB2419462B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

There is disclosed a method of extracting ions comprising the steps of: providing a source of ions; entraining said ions in a laminar flow of a carrier gas; providing a barrier region in which an electrical field is applied across the laminar flow of carrier gas, the magnitude and direction of the electrical field being selected so as to prevent at least some of the ions entrained in the laminar flow from passing through the electrical field; and varying the electrical field so as to allow ions of chosen characteristics to pass through the electrical field.

Description

GO 2419462 A continuation (74) Agent and/or Address for Service:
Wynne-Jones, Laine & James 22 Rodney Road, CHELTENHAM, Gloucestershire, GL50 1JJ, United Kingdom
GB0600268A 2003-06-06 2004-06-07 Ion extraction Expired - Fee Related GB2419462B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0313016.8A GB0313016D0 (en) 2003-06-06 2003-06-06 Ion extraction
PCT/GB2004/002455 WO2004109741A2 (en) 2003-06-06 2004-06-07 Ion extraction

Publications (3)

Publication Number Publication Date
GB0600268D0 GB0600268D0 (en) 2006-02-15
GB2419462A true GB2419462A (en) 2006-04-26
GB2419462B GB2419462B (en) 2007-02-28

Family

ID=9959440

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0313016.8A Ceased GB0313016D0 (en) 2003-06-06 2003-06-06 Ion extraction
GB0600268A Expired - Fee Related GB2419462B (en) 2003-06-06 2004-06-07 Ion extraction

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB0313016.8A Ceased GB0313016D0 (en) 2003-06-06 2003-06-06 Ion extraction

Country Status (2)

Country Link
GB (2) GB0313016D0 (en)
WO (1) WO2004109741A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2490410A (en) * 2012-04-25 2012-10-31 Bruker Daltonik Gmbh Ion mobility spectrometers with enhanced resolution
US8624180B2 (en) 2011-04-26 2014-01-07 Bruker Daltonik Gmbh Resolution enhancement for ion mobility spectrometers
US8766176B2 (en) 2011-04-26 2014-07-01 Bruker Daltonics, Inc. Spectrum acquisition modes for ion mobility spectrometers using trapped ions

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0424426D0 (en) 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
JP2009532681A (en) * 2006-04-03 2009-09-10 エムディーエス アナリティカル テクノロジーズ， ア ビジネス ユニット オブ エムディーエス インコーポレイテッド， ドゥーイング ビジネス スルー イッツ サイエックス ディビジョン Method and apparatus for providing an ion barrier at the inlet and outlet ends of a mass spectrometer
GB0612503D0 (en) 2006-06-23 2006-08-02 Micromass Ltd Mass spectrometer
DE102007017055B4 (en) * 2007-04-11 2011-06-22 Bruker Daltonik GmbH, 28359 Measuring the mobility of mass-selected ions
GB0723487D0 (en) 2007-11-30 2008-01-09 Micromass Ltd Mass spectrometer
GB0801309D0 (en) * 2008-01-24 2008-03-05 Micromass Ltd Mass spectrometer
US7838826B1 (en) 2008-08-07 2010-11-23 Bruker Daltonics, Inc. Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry
DE102008051695B4 (en) * 2008-09-04 2019-06-06 Bruker Daltonik Gmbh Ion Mobility Measurement at Potential Barrier
GB0817433D0 (en) * 2008-09-23 2008-10-29 Thermo Fisher Scient Bremen Ion trap for cooling ions
DE102009050041B4 (en) * 2009-09-17 2014-12-18 Bruker Daltonik Gmbh High-resolution ion mobility spectrometry
JPWO2012124020A1 (en) * 2011-03-11 2014-07-17 株式会社島津製作所 Mass spectrometer
GB201407611D0 (en) * 2014-04-30 2014-06-11 Micromass Ltd Mass spectrometer with reduced potential drop
WO2015166251A1 (en) 2014-04-30 2015-11-05 Micromass Uk Limited Mass spectrometer with reduced potential drop
DE102014110334A1 (en) * 2014-07-22 2016-01-28 Krohne Messtechnik Gmbh Method for separating electrically charged particles with respect to their energy and energy filters
US9683964B2 (en) * 2015-02-05 2017-06-20 Bruker Daltonik Gmbh Trapping ion mobility spectrometer with parallel accumulation
GB201617710D0 (en) * 2016-10-19 2016-11-30 Micromass Uk Limited Ion separator
GB201904135D0 (en) 2019-03-26 2019-05-08 Thermo Fisher Scient Bremen Gmbh Interference suppression in mass spectrometers
US11600480B2 (en) 2020-09-22 2023-03-07 Thermo Finnigan Llc Methods and apparatus for ion transfer by ion bunching
EP4089408A1 (en) 2021-05-14 2022-11-16 Thermo Finnigan LLC Flow recirculation for mobility separation improvement

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935452A (en) * 1973-11-14 1976-01-27 Barringer Research Limited Quadrupole mobility spectrometer
US4283626A (en) * 1979-11-08 1981-08-11 Extranuclear Laboratories, Inc. Methods and apparatus for analysis of mixtures by mass spectrometry
US5847386A (en) * 1995-08-11 1998-12-08 Mds Inc. Spectrometer with axial field
US6486469B1 (en) * 1999-10-29 2002-11-26 Agilent Technologies, Inc. Dielectric capillary high pass ion filter
US20020175279A1 (en) * 2001-05-25 2002-11-28 James Hager Method of mass spectrometry, to enhance separation of ions with different charges

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935452A (en) * 1973-11-14 1976-01-27 Barringer Research Limited Quadrupole mobility spectrometer
US4283626A (en) * 1979-11-08 1981-08-11 Extranuclear Laboratories, Inc. Methods and apparatus for analysis of mixtures by mass spectrometry
US5847386A (en) * 1995-08-11 1998-12-08 Mds Inc. Spectrometer with axial field
US6486469B1 (en) * 1999-10-29 2002-11-26 Agilent Technologies, Inc. Dielectric capillary high pass ion filter
US20020175279A1 (en) * 2001-05-25 2002-11-28 James Hager Method of mass spectrometry, to enhance separation of ions with different charges

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
D Gerlich, 'State-Selected and Stat-to-State Ion-Molecule Reaction Dynamics. Part 1: Experiment', published 1992, Wiley, pages 1-176 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8624180B2 (en) 2011-04-26 2014-01-07 Bruker Daltonik Gmbh Resolution enhancement for ion mobility spectrometers
US8766176B2 (en) 2011-04-26 2014-07-01 Bruker Daltonics, Inc. Spectrum acquisition modes for ion mobility spectrometers using trapped ions
GB2490387B (en) * 2011-04-26 2017-09-13 Bruker Daltonik Gmbh Ion mobility spectrometer and method of measuring an ion mobility spectrum
GB2490410A (en) * 2012-04-25 2012-10-31 Bruker Daltonik Gmbh Ion mobility spectrometers with enhanced resolution
GB2490410B (en) * 2012-04-25 2018-07-04 Bruker Daltonik Gmbh Ion mobility spectrometers with enhanced resolution

Also Published As

Publication number Publication date
WO2004109741A3 (en) 2005-11-24
GB0313016D0 (en) 2003-07-09
WO2004109741A2 (en) 2004-12-16
GB0600268D0 (en) 2006-02-15
GB2419462B (en) 2007-02-28

Similar Documents

Publication Publication Date Title
GB2419462A (en) Ion extraction
WO2004017041A3 (en) High resolution flow cytometer
AU2001294017A1 (en) A method for controlling access to protected content
AU2003217372A1 (en) Dispersions containing bicomponent fluoropolymer particles and use thereof
GB2386456A (en) Computer system with operating system on a ram-disk
WO1999034315A3 (en) Use of inorganic particles and method for marking and identifying a substrate or an article
EP1681465A3 (en) Systems and methods for plasma propulsion
WO2005045580A3 (en) System and method for a unified composition engine in a graphics processing system
MXPA01003595A (en) Object-based numeric analysis engine.
WO2002093148A3 (en) A method of operating a mass spectrometer to suppress unwanted ions
WO2003067237A3 (en) Faims apparatus and method using carrier gases that contain a trace amount of a dopant species
WO2005074633A3 (en) Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
EP1619118A3 (en) Wing enhancement through ion entrainment of media
WO2004057638A3 (en) Method and apparatus for aerodynamic ion focusing
WO2003104848A3 (en) Methods for sem inspection of fluid containing samples
EP1280184A3 (en) Inspecting system for particle-optical imaging of an object, deflection device for charged particles and method for operating the same
WO2008051616A3 (en) Organic-inorganic hybrid nanomaterials and method for synthesizing same
WO2008036410A3 (en) Methods and compositions for treating amyotrophic lateral sclerosis (als)
GB2405738A (en) Gaming device having an incrementing award bonus scheme
ATE290298T1 (en) METHOD AND SYSTEM FOR CONTROLLING AN ADDITIONAL DEVICE THROUGH A SIM CARD, AND CORRESPONDING DEVICES
ATE288130T1 (en) CORONA ION SOURCE
TR200401706T4 (en) Dispersion of more environmentally compatible polymers for fire prevention and fire fighting
TW200510715A (en) Dielectrophoretic particle profiling system and method
ATE493751T1 (en) IDENTIFICATION OF MODIFIED PEPTIDES BY MASS SPECTROMETRY
WO2004016160A3 (en) Redox polymer nanoparticles

Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20230607