GB2415905A - Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising prenyl flavonoids - Google Patents

Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising prenyl flavonoids

Info

Publication number
GB2415905A
GB2415905A GB0520247A GB0520247A GB2415905A GB 2415905 A GB2415905 A GB 2415905A GB 0520247 A GB0520247 A GB 0520247A GB 0520247 A GB0520247 A GB 0520247A GB 2415905 A GB2415905 A GB 2415905A
Authority
GB
United Kingdom
Prior art keywords
cancer
compositions
botanical extract
phytoestrogenic
extract compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0520247A
Other versions
GB2415905B (en
GB0520247D0 (en
Inventor
Sophie Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEDICAL RES AND EDUCATION TRUS
Original Assignee
MEDICAL RES AND EDUCATION TRUS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDICAL RES AND EDUCATION TRUS filed Critical MEDICAL RES AND EDUCATION TRUS
Publication of GB0520247D0 publication Critical patent/GB0520247D0/en
Publication of GB2415905A publication Critical patent/GB2415905A/en
Application granted granted Critical
Publication of GB2415905B publication Critical patent/GB2415905B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A compositon having phytoestrogenic and anti-cancer activity is described. The composition comprises wogonin, isoliquiritigenin, coumestrol, their pharmaceutically acceptable salts or esters, their selectively substituted analogs, or combinations thereof. The compositions may also include an anti-cancer agent and/or an immune stimulant. A method for treating or preventing cancer or an estrogen-related disorder includes administering a therapeutically effective amount of the compositions is described. The compositions are particularly useful in the treatment of hormone-related cancers.
GB0520247A 2003-03-06 2003-08-01 Botanical extract compositions and methods of use Expired - Fee Related GB2415905B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38440503A 2003-03-06 2003-03-06
PCT/US2003/024088 WO2004080474A1 (en) 2003-03-06 2003-08-01 Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising prenyl flavonoids

Publications (3)

Publication Number Publication Date
GB0520247D0 GB0520247D0 (en) 2005-11-16
GB2415905A true GB2415905A (en) 2006-01-11
GB2415905B GB2415905B (en) 2007-10-03

Family

ID=32987291

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0520247A Expired - Fee Related GB2415905B (en) 2003-03-06 2003-08-01 Botanical extract compositions and methods of use

Country Status (4)

Country Link
AU (1) AU2003269928A1 (en)
DE (1) DE10394175T5 (en)
GB (1) GB2415905B (en)
WO (1) WO2004080474A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007053915A2 (en) * 2005-11-09 2007-05-18 Universiteit Gent Naringenin derivatives with selectivity on ers
GB0609386D0 (en) * 2006-05-11 2006-06-21 Active Botan Ltd Treating drug resistant cancers
WO2010052734A1 (en) * 2008-11-06 2010-05-14 Council Of Scientific & Industrial Research Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders
TWI382846B (en) * 2009-10-07 2013-01-21 Univ China Medical Pharmaceutical compositions and extracts for inhibiting formation and/or activation of osteoclasts and uses of the same
CN102516301B (en) * 2011-11-28 2016-08-03 江苏天地人和药业有限公司 Wogonin derivant for treatment
EP2941421A4 (en) * 2013-01-07 2016-09-21 Bg Negev Technologies & Applic Ltd Coumestan, coumestrol, coumestan derivatives and processes of making the same and uses of same
AU2015228775B2 (en) * 2014-03-13 2020-04-02 Procare Health Iberia, S.L. Topical compositions comprising extract of Coriolus versicolor for autoimmunity enhancement
CN104491676A (en) * 2014-11-26 2015-04-08 孙长侠 Goiter-treating stasis-removing soup
CN109991347B (en) * 2017-12-30 2021-10-08 苏州唐锟辰新能源科技有限公司 HPLC fingerprint spectrum establishment method of eclipta medicinal material

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09301915A (en) * 1996-05-08 1997-11-25 Sankyo Co Ltd Flavone and naphthalene derivative
EP1159963A1 (en) * 2000-06-02 2001-12-05 Protein Technologies International, Inc. Composition for and method of preventing or treating breast cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT656786E (en) * 1992-05-19 2004-11-30 Novogen Res Pty Ltd USE OF PHYSIESTROGENIC EXTRACTS OF SOYBEAN ISOFLAVONE OR CLOVER
ATE361746T1 (en) * 2002-03-06 2007-06-15 Medical Res And Education Trus BOTANICAL EXTRACT WITH ANTI-CANCER ACTIVITY CONTAINING ISOLIQUIRITIGENIN
IL148825A0 (en) * 2002-03-21 2002-09-12 Yeda Res & Dev Derivatives of isoflavones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09301915A (en) * 1996-05-08 1997-11-25 Sankyo Co Ltd Flavone and naphthalene derivative
EP1159963A1 (en) * 2000-06-02 2001-12-05 Protein Technologies International, Inc. Composition for and method of preventing or treating breast cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Anticancer Research, Vol. 20, No. 4, 2000, (Fukai, Toshio et al), pages 2525-2536 *
Patent Abstracts of Japan, Vol. 1998, No. 3, (1998-02-27) & JP 09301915 A (SANKYO CO LTD), (1997-11-25) *
Phytochemistry, Vol. 61, No. 7, 2002, (Jang Dae Sik et al), pages 867-872 *

Also Published As

Publication number Publication date
GB2415905B (en) 2007-10-03
WO2004080474A1 (en) 2004-09-23
DE10394175T5 (en) 2006-08-03
AU2003269928A1 (en) 2004-09-30
GB0520247D0 (en) 2005-11-16

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20130801