GB2414558A - Monitoring changes in composition or concentration of a fluid - Google Patents
Monitoring changes in composition or concentration of a fluid Download PDFInfo
- Publication number
- GB2414558A GB2414558A GB0323886A GB0323886A GB2414558A GB 2414558 A GB2414558 A GB 2414558A GB 0323886 A GB0323886 A GB 0323886A GB 0323886 A GB0323886 A GB 0323886A GB 2414558 A GB2414558 A GB 2414558A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fluid
- frequency
- concentration
- changes
- aforesaid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 45
- 239000000203 mixture Substances 0.000 title claims abstract description 22
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 239000000470 constituent Substances 0.000 claims abstract description 36
- 238000001228 spectrum Methods 0.000 claims abstract description 14
- 210000004369 blood Anatomy 0.000 claims abstract description 12
- 239000008280 blood Substances 0.000 claims abstract description 12
- 210000001124 body fluid Anatomy 0.000 claims abstract description 6
- 239000010839 body fluid Substances 0.000 claims abstract description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 5
- 239000008103 glucose Substances 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 15
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 claims description 7
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 238000004804 winding Methods 0.000 claims description 5
- 238000000338 in vitro Methods 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 4
- 238000005259 measurement Methods 0.000 claims description 4
- 210000000170 cell membrane Anatomy 0.000 claims description 3
- 235000012000 cholesterol Nutrition 0.000 claims description 3
- 230000005672 electromagnetic field Effects 0.000 claims description 3
- 210000003743 erythrocyte Anatomy 0.000 claims description 3
- 150000002632 lipids Chemical class 0.000 claims description 3
- 239000013598 vector Substances 0.000 claims description 3
- 102000017011 Glycated Hemoglobin A Human genes 0.000 claims description 2
- 108010014663 Glycated Hemoglobin A Proteins 0.000 claims description 2
- 210000003423 ankle Anatomy 0.000 claims description 2
- 230000002596 correlated effect Effects 0.000 claims description 2
- 230000005284 excitation Effects 0.000 claims description 2
- 210000000707 wrist Anatomy 0.000 claims description 2
- 241000272875 Ardeidae Species 0.000 claims 1
- 244000025254 Cannabis sativa Species 0.000 claims 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 claims 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 claims 1
- 241000283907 Tragelaphus oryx Species 0.000 claims 1
- 235000009120 camo Nutrition 0.000 claims 1
- 235000005607 chanvre indien Nutrition 0.000 claims 1
- 239000002361 compost Substances 0.000 claims 1
- 210000004247 hand Anatomy 0.000 claims 1
- 239000011487 hemp Substances 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 239000006249 magnetic particle Substances 0.000 description 2
- 239000012491 analyte Substances 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Ecology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
An apparatus for tracking changes in composition or concentration of a fluid or of one or more component parts of the fluid comprises a plurality of tuned radio frequency transformers (A, B) with a field pattern proximal the fluid sample such that changes in the sample result in changes in the frequency bandwidth or power-bandwidth spectrum of the transformers. This may be measured directly or indirectly and used to calculate the fluid concentration or composition or the amount of a constituent part in the sample. The apparatus is useful for monitoring body fluids such as blood for constituents such as glucose or haemoglobin. The different transformers may operate at different frequencies to monitor different components of the fluid.
Description
24 1 4558 Apparatus and Method for tracking changes in composition or
concentration of a fluid or one or more component parts thereof.
This invention relates to an apparatus and method for tracking changes in the composition or concentration of a fluid or the same in one or more component parts thereof wherein preferably the fluid is a body fluid such as blood and preferably at one component part there of is glucose Several such inventions have appeared recently in relation to proposed noninvasive blood glucose (sugar) measurement all of which appear to employ variants of capacitive electrode systems These have the disadvantage that they are affected by sweat or can only be worn in prominent places on the body such as the ear lobe US 5,001,424 discloses a three coil magnetic field system to detect magnetic particles in a fluid oil based on mutual inductance of non- resonant coils Advantageously according to the present invention is provided an apparatus for tracking changes in the composition or concentration of a fluid or of one or more of the constituent components thereof comprising a plurality of tuned radio frequency transformer systems, which advantageously also exhibit via both electromagnetic field vectors sensitivity to non- magnetic particles and solutes and which can either envelope a body past such as a wrist or ankle, or be placed with its active field pattern proximal with and penetrating into the body part and/or fluid under investigation and comprising means for bringing the said fluid proximal with but electrically insulated from the said transformer systems such that the above said fluid changes manifest concurrent changes in the radio frequency bandwidth and/ or frequency - power spectrum or any part thereof available to each transformer system within the said plurality which may be directly or indirectly measured from any part of the each said transformer system additionally said apparatus has optional means for storing or recording the same and further has means of calculating there from, with or without using stored or recorded data, and displaying the result as equal to or in a format proportional to or otherwise correlated in terms of fluid concentration or composition or the same for (a) chosen aforesaid constituent(s) thereof. In this present apparatus the fluid is preferably though not exclusively a bio fluid such as for example blood in vivo or in vitro Further in this present apparatus one of the aforesaid constituents is preferably though not exclusively d-glucose.
In this present apparatus according to the present in invention, the aforesaid means for measuring radio frequency bandwidth or frequency /power spectrum is achieved measuring any combination of the following: resonant frequency of each transformer system as a whole; resonant half width or bandwidth of each transformer system as a whole, quality factor of each said system; two or more entry (primary) conditions and /or temporal changes therein such as amplitude, phase, frequency, excitation power level or emergent conditions (secondary) measurement may be any of the same as for primary. In the present apparatus each said transformer system may operate with a significantly different centre radio frequency or band of radio frequencies Further according to the present invention each said centre frequency or frequency band may track the composition or concentration of a different aforesaid constituent Further and alternatively according to the present invention each said centre radio frequency or frequency band may track the concentration or composition of multiple constituents but at different weightings per constituent at each said frequency or within each said frequency band Further according to this present invention the power level applied to the primary winding of each said transformer system may differ and be varied linearly or non -linearly with time Further according to this present invention the waveform applied to the primary of each said transformer system may be sinusoidal or non -sinusoidal in form Further according to this present invention the frequency of the aforesaid waveform may be constant or may vary in a linear or non -linear manner. Further according to this present invention the apparatus may contain a memory with stored data pertinent to the fluid system being tracked or similar such fluid system and/or with stored data pertinent to the behaviour of the plural transformer system under various control and/or calibration conditions Further according to the present invention any of the variants described above may be employed advantageously in determining the composition or concentration of the aforesaid fluid or its constituent(s) by means of enhanced calculation or computation Further in another embodiment this present invention provides a method for tracking changes in the composition or concentration of a fluid or of one or more of the constituent components thereof comprising the steps of firstly bringing the said fluid proximal with the active field pattern of a plurality of radio frequency transformer systems such that concurrently above said changes manifest changes in the radio frequency bandwidth of each transformer system, secondly providing the steps of measuring the said bandwidth or power-frequency spectrum in terms of two or more selected parameters of the said transformer system(s) and changes therein and optionally recording the same and a further step of calculating on the same with or without use of stored or recorded data and displaying the outcome of said calculation in units equal to or in a format proportional to or otherwise in terms of the aforesaid fluid concentration or composition or the same for (a) chosen aforesaid constituent (s) thereof. This present method the fluid is preferably though not exclusively a bio fluid such as for example blood in vivo or in vitro and one of the aforesaid constituents is preferably though not exclusively d-glucose.
Further in an alternative embodiment present method can be used to study the effects of glucose as d-glucose or as glycosylated Hemoglobin ( Hlac) measured directly or due to their effects on erythrocyte cell membrane rigidity penneably and Iysis. In a further embodiment one of the aforesaid constituents may be blood fat,lipid or cholesterol.
The present invention will now be described by way of reference to the drawings in which figure I shows a schematic of a single tuned transformer system proximal to a fluid and the concept of mutual coupling according to the present in invention, Figure 2 shows the concept of employing more than one such transformer system, Figure 3 shows the concept of interrogating such a transformer system at its primary and or secondary winding and the symbols of some possible measurands that give a measure of frequency bandwidth of power -t'requency spectrum according to the present invention, Figure 4 shows one practical example apparatus embodiment of the present invention Referring to the drawings then Figure I shows a single radio frequency transformer system having its two parts A and B proximal to a fluid As A an B are brought closer together their Q skirts or bandwidth profiles overlap, C The degree of overlap will be effected by the components of the fluid Referring to figure 2, this shows how according to the present invention two such transformer systems, preferably though not exclusively at dit'ferent centre radio frequencies or operating on different frequency bands can both have fields proximal with the fluid or share the same fluid core.
In figure 3 the concept of measuring the frequency,f, power, P. Amplitude, A, or phase, phi, at the primary of the said transformer system is shown, likewise t'or the secondary The concept of measuring the overall system quality factor Q or half power bandwidth, delta f I/2 is also shown.
Figure 4 shows one practical example embodiment of the present invention R f generator I drives transformer plurality 2 which are in turn is coupled to radio frequency processing unit 3 via A/D converter 4 to central Processor 5 Data may be stored in or recovered from memory 6 and used in processing 5 to give display of fluid or its constituent(s) thereof composition(s) ,concentration(s) of which is (are) being tracked. Display may give continuous indication or may give indications at pre- determined measurement intervals according to or not according to memory element Plural transformer systems at 2 may enhance the process should multiple analyte tracking be required Processor 6 pert'orms calculations and enhanced calculations and controls r f. generator and r f. processing circuits for transformer bandwidth assessments. Individual transformers of plurality at 2 may be concurrently or sequentially energised Note in an alternative embodiment according to the present in invention, the whole transformer plurality or any individual transformer within it can comprise auto-transt'ormers or transformers(s) with otherwise one or more split windings. Those skilled in the art that the should note that the use of alternative electronic circuits to achieve the same ends as the embodiment at fig 4 above is envisioned by the present inventor and such use does not depart from the present invention or its claims herein below
Claims (1)
- Apparatus for tracking changes in the composition or concentration of a fluid or of one or more of the constituent components thereof is provided comprising means for bringing the said fluid proximal with the active field pattern of a plurality of tuned radio frequency transformers such that the above said changes manifest concurrent changes in the transformer system's frequency bandwidth or power -bandwidth spectrum which is measured directly or indirectly and used in calculation or computation with or without using stored or recorded data, and with means of displaying the result as equal to or in a format proportional to or otherwise correlated in terms of fluid concentration or composition or the same for (a) chosen aforesaid constituent(s) thereof 2. Apparatus as in claim I above but wherein fluid is preferably though not exclusively a bio fluid such as t'or example blood in vivo or in vitro.3. Apparatus as in claim 2 above wherein one of the aforesaid constituents is preferably though not exclusively d-glucose 4 Apparatus as in any of claims 1-3 above wherein aforesaid means for measuring frequency bandwidth or power-frequency spectrum and changes therein is achieved by measuring any combination of the following resonant frequency of each transformer system as a whole, resonant half - width or bandwidth of each transformer system as a whole; quality t'actor of each said system; two or more entry (primary) conditions and /or changes therein such as amplitude, phase, t'requency, excitation power level or emergent conditions (secondary) measurement may be any of the same as for primary Apparatus as in any of claims 1-4 above wherein each said transformer system may operate with a significantly different centre radio frequency or band of radio frequencies 6 Apparatus as in claim 5 above wherein according to the present invention each said centre frequency or frequency band may track the composition or concentration of a different aforesaid constituent.7. Apparatus as in claim 5 above wherein each said centre radio frequency or frequency band may track the concentration or composition of multiple constituents but at different weightings per constituent at each said frequency or within each said frequency band 8 Apparatus according to any of claims 1-7 above wherein the power level applied to the primary winding of each said transformer system may differ and may be varied linearly or non -linearly with thee 9 Apparatus according to any of clahns 1-8 above wherein the waveform applied to the primary of each said transformer system may be sinusoidal or non -sinusoidal in form Apparatus according to any of claims 1-9 above wherein the frequency of the aforesaid waveform may be constant or may vary in a linear or non -linear manner.11 Apparatus according to any of claims I-10 above wherein a memory with stored data pertinent to the fluid system being tracked or similar such fluid system is contained 12. Apparatus in which any variant described within claims 5-1 1 above may be employed advantageously in determining the composition or concentration of the aforesaid fluid or its constituent(s) by means of enhanced calculation, said transformer systems being simultaneously or sequentially energised 13 Apparatus as in any of claims I -12 the transformer systems of which configured as to envelope a body part such as a wrist or an ankle 1 4Method for tracking changes in the composition or concentration of a fluid or of one or more of the constituent components thereof comprising the steps of firstly bringing the said fluid proximal with the active field pattern of a plurality of radio frequency transformer systems such that concurrently above said changes manifest changes in the frequency bandwidth or power -bandwidth spectrum of each said transformer system, measuring the same directly or indirectly and optionally recording the same and a further step of calculating on the same with or without use of stored or recorded data and displaying the outcome of said calculation in units equal to or in a format proportional to or otherwise in terms of the aforesaid fluid concentration or composition or the same for (a) chosen aforesaid constituent (s) thereof.Method as in claim 14 above wherein fluid is preferably though not exclusively a bio fluid such as for example blood in vivo or in vitro.16 Method as in claim 15 wherein one of the aforesaid constituents is preferably though not exclusively d-glucose.17 Method as in 15 or 16 above wherein effects of glucose as d-glucose or as glycosylated Hemoglobin ( H I ac)measured directly or due to their effects on erythrocyte cell membrane rigidity,penneably and Iysis.18 Method as in claim 15 above but wherein one of constituents is blood fat, lipid or cholesterol Amendments to the claims have been filed as follows 1. Apparatus for tracking changes in the composition or concentration of one or more multiple constituent components ova body fluid or blood emilprising means for bringing the said body fluid proximal with the electromagnetic field vectors ot'a plurality (two or more pairs) of' tuned radio frequency transformers, means for causing each said pair to operate with substantially different centre frequencies on substantially dil'terent tequeney hands, such that above said changes in said components manifest cmeurrent changes In each said transl'ormers' power bandwidth spectrum such that each said eentre frequency or fretineney band may track the emilpositon car concentration of a dl'l'erent al'oresacl constituent or alternatively that each said eentre frequency or frequency band may track the emeentration or compostm, of multiple constituents hut at different weightings per eonsttueut at each said frequency band, apparatus additionally comprising means for measuring said spectrum of each said transt'onner pair and means for using said spectra in calculation or . . eomputatim with or without use of stored data so as to bring about a numeric result equal to coneentTaton odor us a format proportional thereto a chosen 1 aforesaid emsttuent(s). 12. Apparatus as in eland 1 above wherein one of the said constituents is d- glueose.3. Apparatus as In claim I or 2 above wherein the power level in the primary winding of each al'oresaid tran.st'ormer system may dl'l'cr. iO4. Apparatus as any claim 1-3 above wherein the power level may be varied linearly with time.5. Apparatus as any claim 1-3 above wherein the power level may be varied non- Ililearly with time.6. Apparatus as In any ol claims 1-5 herelil above wherein the primary waveform Is sinusoidal.7. Apparatus as in ally of claims 1-5 herons above wherein the primary waveform IS 11011- SlilUSOILial.8. Appalatus as in any of claims 1-7 herein above wherein the primary waveform frequency Is constant.9. Appalatus as in any of claims 1-7 herein above wherelil the primary waveform . a a Frequency varies linearly. . . 10. Apparatus as in any of clangs 1-7 herein above wherein the primary waveform a ha a. Frequency varies non 1 inearl y. t.11. Apparatus as In any ol claims 1-10 wherein a memory with stored data pertinent to the fluid hemp tracked is employed.] 2. Apparatus as in any of claims I - I I colifigul-eci to envelope a body part. 1 11 3.Method for tracking changes In the composition or concentration of one or more multiple constituent components ol'a body fluid or blood comprising a first step of bringing the said body fluid proximal with the electromagnetic field vectors of a plurality (two or more pairs) ol' tuned radio frequency transformers, a second step of causing each said pair to operate with substantially different centre frequencies on substantially different fi-equency bands, such that above said changes In said components rnaml'est concurrent changes in each said transformers' power bandwidth spectrum such that each said centre frequency or- frequency band may track the compo.siton or concentration.1'a dil'ferent aforesaid constituent or- alternatively that each said centre frequency or frequency band may track the concentration or- compost.on ol' multiple constituents but at dl'l'erent weightings per constituent at each said frequency band, method additionally comprising third step of rneasurng said spectrum Cal' each said transformer pair and a i. . I. lo. fourth step ol'calculatmg ol computing l'rom said spectra with or without use of stored data a numeric result equal L:' concentration of or hi a format proportional thereto a chosen af'oresad constituent(s). 614. Method as in claim 13 above wherein one of said constituents is dglucose.Method as in claim 13 or 14 above wherein el'fects of d-glucose or glycosylated Haemoglobm (H I ac) are measured due to their effects on erythrocyte cell membrane rigidity,permeability and Iyss.16. Method as in nay ol' 13-15 wherem one ol' constituents Is blood lot, lipid or cholesterol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0323886A GB2414558B (en) | 2003-10-10 | 2003-10-10 | Apparatus and method for tracking changes in composition or concentration of a fluid or one or more component parts thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0323886A GB2414558B (en) | 2003-10-10 | 2003-10-10 | Apparatus and method for tracking changes in composition or concentration of a fluid or one or more component parts thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0323886D0 GB0323886D0 (en) | 2003-11-12 |
| GB2414558A true GB2414558A (en) | 2005-11-30 |
| GB2414558B GB2414558B (en) | 2006-04-19 |
Family
ID=29433760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0323886A Expired - Fee Related GB2414558B (en) | 2003-10-10 | 2003-10-10 | Apparatus and method for tracking changes in composition or concentration of a fluid or one or more component parts thereof |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2414558B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017114566A1 (en) * | 2017-06-29 | 2019-01-03 | Aixtron Se | Method for determining the vapor concentration using the magnetic properties of the vapor |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113239645A (en) * | 2021-05-25 | 2021-08-10 | 中海石油气电集团有限责任公司 | System and method for dynamically tracking and calculating natural gas components in natural gas pipe network in real time |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1574681A (en) * | 1977-01-22 | 1980-09-10 | Labora Mannheim Gmbh | Device for determining the blood sedimentation rate |
| GB2064127A (en) * | 1979-09-26 | 1981-06-10 | Trw Inc | Subsea hydrocarbon sensor system |
| US4651092A (en) * | 1982-09-22 | 1987-03-17 | International Business Machines Corporation | Method of determining dispersion, particle density or viscosity of resin/solvent mixture containing magnetic particles |
| US5001424A (en) * | 1989-02-03 | 1991-03-19 | Product Resources, Inc. | Apparatus for measuring magnetic particles suspended in a fluid based on fluctuations in an induced voltage |
| AT395075B (en) * | 1986-12-17 | 1992-09-10 | Chira Irvin Sorin Dipl Ing | METHOD AND DEVICE FOR QUANTITATIVE DETERMINATION OF ELEMENTS AND SUBSTANCES IN AQUEOUS SOLUTIONS |
| GB2260407A (en) * | 1991-10-10 | 1993-04-14 | Christopher Barnes | Contactless measurement of physical parameters of samples |
| EP0630471A1 (en) * | 1992-03-10 | 1994-12-28 | BARNS, Christopher | Apparatus for determining the physical and/or chemical properties of a sample, particularly of blood |
| US5583432A (en) * | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
| WO2004028358A1 (en) * | 2002-09-24 | 2004-04-08 | Pendragon Medical Ltd. | Device for the measurement of glucose concentrations |
-
2003
- 2003-10-10 GB GB0323886A patent/GB2414558B/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1574681A (en) * | 1977-01-22 | 1980-09-10 | Labora Mannheim Gmbh | Device for determining the blood sedimentation rate |
| GB2064127A (en) * | 1979-09-26 | 1981-06-10 | Trw Inc | Subsea hydrocarbon sensor system |
| US4651092A (en) * | 1982-09-22 | 1987-03-17 | International Business Machines Corporation | Method of determining dispersion, particle density or viscosity of resin/solvent mixture containing magnetic particles |
| AT395075B (en) * | 1986-12-17 | 1992-09-10 | Chira Irvin Sorin Dipl Ing | METHOD AND DEVICE FOR QUANTITATIVE DETERMINATION OF ELEMENTS AND SUBSTANCES IN AQUEOUS SOLUTIONS |
| US5001424A (en) * | 1989-02-03 | 1991-03-19 | Product Resources, Inc. | Apparatus for measuring magnetic particles suspended in a fluid based on fluctuations in an induced voltage |
| GB2260407A (en) * | 1991-10-10 | 1993-04-14 | Christopher Barnes | Contactless measurement of physical parameters of samples |
| EP0630471A1 (en) * | 1992-03-10 | 1994-12-28 | BARNS, Christopher | Apparatus for determining the physical and/or chemical properties of a sample, particularly of blood |
| US5583432A (en) * | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
| WO2004028358A1 (en) * | 2002-09-24 | 2004-04-08 | Pendragon Medical Ltd. | Device for the measurement of glucose concentrations |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017114566A1 (en) * | 2017-06-29 | 2019-01-03 | Aixtron Se | Method for determining the vapor concentration using the magnetic properties of the vapor |
| WO2019002280A1 (en) | 2017-06-29 | 2019-01-03 | Aixtron Se | Method for determining the vapour concentration using the magnetic properties of the vapour |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0323886D0 (en) | 2003-11-12 |
| GB2414558B (en) | 2006-04-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10159413B2 (en) | Apparatus and method for non-invasive measurement of blood parameters | |
| Choi et al. | Lower levels of glutathione in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T | |
| EP1141685B1 (en) | Impedance measurements of bodily matter | |
| US20210199736A1 (en) | Method and system for in-vivo, and non-invasive measurement of metabolite levels | |
| EP3205266B1 (en) | Diagnostic system for detection of fluid changes | |
| US20100303321A1 (en) | System and Method for Conducting Multiplexed Electrical Impedance Tomography | |
| EP3556286B1 (en) | Impedance spectroscopy and optical technique-based multi-sensor noninvasive blood sugar detection apparatus | |
| CA2222742A1 (en) | Method of internal magnetic resonance imaging and spectroscopic analysis and associated apparatus | |
| WO2005117696A3 (en) | Method and apparatus for generating a therapeutic magnetic field | |
| Cudalbu et al. | Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized 1H and 15N NMR spectroscopy | |
| Sadaghiani et al. | Lesions to the fronto-parietal network impact alpha-band phase synchrony and cognitive control | |
| Moser et al. | Windows on the human body–in vivo high-field magnetic resonance research and applications in medicine and psychology | |
| Houtman et al. | pH heterogeneity in tibial anterior muscle during isometric activity studied by31P-NMR spectroscopy | |
| GB2414558A (en) | Monitoring changes in composition or concentration of a fluid | |
| US20040104736A1 (en) | Apparatus and method for analysing fluids | |
| US7382125B2 (en) | Tuned frequency portal for power transfer in MRI environment | |
| Lin et al. | 2D CSI proton MR spectroscopy of human spinal vertebra: feasibility studies | |
| Henning et al. | 1H MRS in the human spinal cord at 7 T using a dielectric waveguide transmitter, RF shimming and a high density receive array | |
| Kang et al. | Intracranial microvascular imaging at 7 T MRI with transceiver RF coils | |
| WO2011040439A1 (en) | Method for measuring and imaging temperature distribution in tissue | |
| Sotelo et al. | Metabolomics using nuclear magnetic resonance (NMR) | |
| Deborne et al. | Proton MRS on sub‐microliter volume in rat brain using implantable NMR microcoils | |
| KR100680699B1 (en) | A measurement method of biochemical change in skin tissue using magnetic resonance spectroscopy | |
| Altehoefer et al. | Characterization of hematopoietic bone marrow in male professional cyclists by magnetic resonance imaging of the lumbar spine | |
| Shao et al. | Computer-assisted evaluation of aortic stiffness using data acquired via magnetic resonance |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20081010 |