GB2406195A - Perturbation effect recognition in a biological system - Google Patents

Perturbation effect recognition in a biological system Download PDF

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Publication number
GB2406195A
GB2406195A GB0501539A GB0501539A GB2406195A GB 2406195 A GB2406195 A GB 2406195A GB 0501539 A GB0501539 A GB 0501539A GB 0501539 A GB0501539 A GB 0501539A GB 2406195 A GB2406195 A GB 2406195A
Authority
GB
United Kingdom
Prior art keywords
biological system
sample
perturbation
perturbation effect
effect recognition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0501539A
Other versions
GB0501539D0 (en
Inventor
Edward Clarke Conley
Gareth Bray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Original Assignee
Amersham Biosciences UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences UK Ltd filed Critical Amersham Biosciences UK Ltd
Publication of GB0501539D0 publication Critical patent/GB0501539D0/en
Publication of GB2406195A publication Critical patent/GB2406195A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Systems for profiling the effect of perturbations in a biological system comprising means for recording signals from a sample of the biological system, means for applying a perturbation to said sample and means for comparing signals able to compare signals from said sample before said perturbation is applied to said sample with signals from said sample after said perturbation has been added to said sample. Methods for using said systems are also described.

Description

GB 2406195 A continuation (74) Agent and/or Address for Service: Amersham
PLC Amersham Place, LITTLE CHALFONT, Buckinghamshire, HP7 BOA, United Kingdom
GB0501539A 2002-07-30 2003-07-28 Perturbation effect recognition in a biological system Withdrawn GB2406195A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0217551A GB0217551D0 (en) 2002-07-30 2002-07-30 Perturbation effect recognition
PCT/GB2003/003180 WO2004011939A1 (en) 2002-07-30 2003-07-28 Perturbation effect recognition in a biological system

Publications (2)

Publication Number Publication Date
GB0501539D0 GB0501539D0 (en) 2005-03-02
GB2406195A true GB2406195A (en) 2005-03-23

Family

ID=9941311

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0217551A Ceased GB0217551D0 (en) 2002-07-30 2002-07-30 Perturbation effect recognition
GB0501539A Withdrawn GB2406195A (en) 2002-07-30 2003-07-28 Perturbation effect recognition in a biological system

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0217551A Ceased GB0217551D0 (en) 2002-07-30 2002-07-30 Perturbation effect recognition

Country Status (3)

Country Link
AU (1) AU2003254484A1 (en)
GB (2) GB0217551D0 (en)
WO (1) WO2004011939A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0816511A1 (en) * 1996-06-27 1998-01-07 HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. Method of screening substances
WO1998014780A1 (en) * 1996-10-02 1998-04-09 Michael Dennis Methods of testing antagonists for their abilities to affect the activity of g protein-coupled receptors
WO2001008039A2 (en) * 1999-07-27 2001-02-01 Zeneca Limited Analysis and pattern recognition in large, multidimensional data sets using low-resolution data grouping
WO2001016598A2 (en) * 1999-09-01 2001-03-08 Medalys Corporation High throughput chemical profiling
WO2001042786A2 (en) * 1999-12-09 2001-06-14 Cellomics, Inc. System for cell based screening : cell spreading

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0816511A1 (en) * 1996-06-27 1998-01-07 HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. Method of screening substances
WO1998014780A1 (en) * 1996-10-02 1998-04-09 Michael Dennis Methods of testing antagonists for their abilities to affect the activity of g protein-coupled receptors
WO2001008039A2 (en) * 1999-07-27 2001-02-01 Zeneca Limited Analysis and pattern recognition in large, multidimensional data sets using low-resolution data grouping
WO2001016598A2 (en) * 1999-09-01 2001-03-08 Medalys Corporation High throughput chemical profiling
WO2001042786A2 (en) * 1999-12-09 2001-06-14 Cellomics, Inc. System for cell based screening : cell spreading

Also Published As

Publication number Publication date
WO2004011939A1 (en) 2004-02-05
GB0217551D0 (en) 2002-09-11
AU2003254484A1 (en) 2004-02-16
GB0501539D0 (en) 2005-03-02

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)