GB2402879A - Method of treating pain with botulinum toxin - Google Patents

Method of treating pain with botulinum toxin Download PDF

Info

Publication number
GB2402879A
GB2402879A GB0417048A GB0417048A GB2402879A GB 2402879 A GB2402879 A GB 2402879A GB 0417048 A GB0417048 A GB 0417048A GB 0417048 A GB0417048 A GB 0417048A GB 2402879 A GB2402879 A GB 2402879A
Authority
GB
United Kingdom
Prior art keywords
muscles
botulinum toxin
treating pain
pain
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0417048A
Other versions
GB2402879B (en
GB0417048D0 (en
Inventor
Gregory B Lamb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
1474791 Ontario Ltd
Original Assignee
1474791 Ontario Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002369810A external-priority patent/CA2369810C/en
Application filed by 1474791 Ontario Ltd filed Critical 1474791 Ontario Ltd
Publication of GB0417048D0 publication Critical patent/GB0417048D0/en
Publication of GB2402879A publication Critical patent/GB2402879A/en
Application granted granted Critical
Publication of GB2402879B publication Critical patent/GB2402879B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method of heating pain in provided. The method comprises administering to the intrinsic spinal muscles of a mammal an amount of a toxin sufficient to paralyze the muscles. This prevents the muscles from shortening and can allow healing to occur. The paralyzing agent may use in combination with a growth factor to treat spinal compression. A kit for the treatment of pain by injection of the intrinsic spinal muscles is also provided. The kit comprises a paralyzing agent, an injection syringe with needle, and an acupuncture needle with injector system.

Description

GB 2402879 A continuation (74) Agent and/or Address for Service:
Cruikshank and Fairweather 19 Royal Exchange Square, Glasgow G1 3AE, Scotland, United Kingdom
GB0417048A 2002-01-30 2003-01-29 Use of botulinum toxin for the treatment of spinal compression disorders Expired - Fee Related GB2402879B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002369810A CA2369810C (en) 2002-01-30 2002-01-30 Method of treating pain
PCT/CA2003/000127 WO2003063898A2 (en) 2002-01-30 2003-01-29 Method of treating pain with botulinum toxin

Publications (3)

Publication Number Publication Date
GB0417048D0 GB0417048D0 (en) 2004-09-01
GB2402879A true GB2402879A (en) 2004-12-22
GB2402879B GB2402879B (en) 2006-01-18

Family

ID=32932213

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0417048A Expired - Fee Related GB2402879B (en) 2002-01-30 2003-01-29 Use of botulinum toxin for the treatment of spinal compression disorders

Country Status (2)

Country Link
AU (1) AU2003202374B2 (en)
GB (1) GB2402879B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053005A (en) * 1989-04-21 1991-10-01 Gary E. Borodic Chemomodulation of curvature of the juvenile spine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053005A (en) * 1989-04-21 1991-10-01 Gary E. Borodic Chemomodulation of curvature of the juvenile spine

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Handchirurgie, Mikrochirugie, Plastische Chirugie, Vol 31, No. 2, 1999, (BURG D et al), pages 75-78 *
Mayo Clinic Proceedings, Vol. 75, No. 7, 2000, (GASSNER H.G. et al), pages 701-704 *
Movement Disorders, Vol. 13, No. 3, 1998, (COMELLA C et al), pages 552-555 *
Movement Disorders, Vol. 8, No. 3, 1993, (DAVIS D et al), pages 371-373 *
Neurology, Vol. 56, No. 10, 2001, (FOSTER L et al), pages 1290-1293 *

Also Published As

Publication number Publication date
GB2402879B (en) 2006-01-18
GB0417048D0 (en) 2004-09-01
AU2003202374B2 (en) 2008-05-15

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20190129