GB2400518A - Prism design for optical scanning applications - Google Patents

Prism design for optical scanning applications Download PDF

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Publication number
GB2400518A
GB2400518A GB0416718A GB0416718A GB2400518A GB 2400518 A GB2400518 A GB 2400518A GB 0416718 A GB0416718 A GB 0416718A GB 0416718 A GB0416718 A GB 0416718A GB 2400518 A GB2400518 A GB 2400518A
Authority
GB
United Kingdom
Prior art keywords
prism
optical scanning
scanning applications
prism design
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0416718A
Other versions
GB2400518B (en
GB0416718D0 (en
Inventor
Mark Osborne
Jason Bryant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solexa Ltd Great Britain
Original Assignee
Solexa Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solexa Ltd Great Britain filed Critical Solexa Ltd Great Britain
Publication of GB0416718D0 publication Critical patent/GB0416718D0/en
Publication of GB2400518A publication Critical patent/GB2400518A/en
Application granted granted Critical
Publication of GB2400518B publication Critical patent/GB2400518B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/10—Scanning systems
    • G02B26/108—Scanning systems having one or more prisms as scanning elements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/56—Optics using evanescent waves, i.e. inhomogeneous waves
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/04—Prisms

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Elements Other Than Lenses (AREA)

Abstract

There is disclosed a prism for use in scanning applications such as total internal reflection microscopy in which the prism is translated relative to an incident light beam. A geometry is disclosed which cancels walk of the beam footprint at the base of the prism.

Description

GB 2400518 A continuation (74) Agent and/or Address for Service: Boult
Wade Tennant Verulam Gardens, 70 Gray's Inn Road, LONDON, WC1X BET, United Kingdom
GB0416718A 2002-01-16 2003-01-15 Prism design for optical scanning applications Expired - Lifetime GB2400518B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0200938.9A GB0200938D0 (en) 2002-01-16 2002-01-16 Prism design for scanning applications
PCT/GB2003/000154 WO2003062897A1 (en) 2002-01-16 2003-01-15 Prism design for optical scanning applications

Publications (3)

Publication Number Publication Date
GB0416718D0 GB0416718D0 (en) 2004-09-01
GB2400518A true GB2400518A (en) 2004-10-13
GB2400518B GB2400518B (en) 2005-06-08

Family

ID=9929178

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0200938.9A Ceased GB0200938D0 (en) 2002-01-16 2002-01-16 Prism design for scanning applications
GB0416718A Expired - Lifetime GB2400518B (en) 2002-01-16 2003-01-15 Prism design for optical scanning applications

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB0200938.9A Ceased GB0200938D0 (en) 2002-01-16 2002-01-16 Prism design for scanning applications

Country Status (3)

Country Link
US (2) US7518764B2 (en)
GB (2) GB0200938D0 (en)
WO (1) WO2003062897A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
US7645596B2 (en) 1998-05-01 2010-01-12 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US7897345B2 (en) 2003-11-12 2011-03-01 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US7981604B2 (en) 2004-02-19 2011-07-19 California Institute Of Technology Methods and kits for analyzing polynucleotide sequences
US9096898B2 (en) 1998-05-01 2015-08-04 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules

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* Cited by examiner, † Cited by third party
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US7276720B2 (en) 2004-07-19 2007-10-02 Helicos Biosciences Corporation Apparatus and methods for analyzing samples
DE102005023768B4 (en) * 2005-05-19 2017-06-29 Leica Microsystems Cms Gmbh Method for determining the orientation of molecules in biological samples
US8241573B2 (en) 2006-03-31 2012-08-14 Illumina, Inc. Systems and devices for sequence by synthesis analysis
EP2279268A4 (en) 2008-04-04 2011-12-07 Life Technologies Corp Scanning system and method for imaging and sequencing
US8039817B2 (en) 2008-05-05 2011-10-18 Illumina, Inc. Compensator for multiple surface imaging
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
US9012872B1 (en) 2010-01-15 2015-04-21 Iowa State University Research Foundation, Inc. Auto-calibrated scanning-angle prism-type total internal reflection microscopy for nanometer-precision axial position determination and optional variable-illumination-depth pseudo total internal reflection microscopy
US9428789B2 (en) 2011-03-21 2016-08-30 Biodesy, Inc. Classification of kinase inhibitors using nonlinear optical techniques
JP2012256663A (en) * 2011-06-08 2012-12-27 Nec Corp Optical amplifier and optical amplification method
DE102011051042B4 (en) * 2011-06-14 2016-04-28 Leica Microsystems Cms Gmbh Scanning microscope and method for light microscopic imaging of an object
US8785885B1 (en) * 2013-01-30 2014-07-22 Omnivision Technologies, Inc. Fluorescence imaging module
US9874736B2 (en) * 2013-04-29 2018-01-23 The Regents Of The University Of California Apparatus and method for an inclined single plane imaging microscope box (iSPIM box)
US9352315B2 (en) 2013-09-27 2016-05-31 Taiwan Semiconductor Manufacturing Company, Ltd. Method to produce chemical pattern in micro-fluidic structure
JP6649904B2 (en) 2014-06-30 2020-02-19 バイオデシー， インコーポレイテッド Systems and methods for high-throughput analysis of conformations in biological entities
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3278087A4 (en) 2015-04-02 2018-12-19 Biodesy, Inc. Methods for determining protein structure using a surface-selective nonlinear optical technique
CN104990907B (en) 2015-07-01 2018-05-08 上海睿钰生物科技有限公司 Automated multi-channel class streamed image system of fluorescence analysis
EP3455628A4 (en) 2016-05-09 2019-12-04 Biodesy, Inc. Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques
EP3538941A4 (en) 2016-11-10 2020-06-17 The Trustees of Columbia University in the City of New York Rapid high-resolution imaging methods for large samples
EP3635372A4 (en) * 2017-06-09 2021-05-26 Verivin Ltd. Characterization of liquids in sealed containers
TWI815252B (en) * 2021-12-22 2023-09-11 財團法人工業技術研究院 Light emission module, light detection and ranging system and light scanning method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980831A (en) * 1996-06-17 1999-11-09 Braiman; Mark S. Support planar germanium waveguides for infrared evanescent-wave sensing
US6144498A (en) * 1998-06-11 2000-11-07 Optical Coating Laboratory, Inc. Color separation prism assembly and method for making same
US6327238B1 (en) * 1997-08-29 2001-12-04 Matsushita Electric Industrial Co., Ltd. Optical disk device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610391A (en) * 1994-08-25 1997-03-11 Owens-Brockway Glass Container Inc. Optical inspection of container finish dimensional parameters
JPH109016A (en) 1996-06-24 1998-01-13 Nissan Motor Co Ltd Starting fuel injection control device for internal combustion engine
JPH1090169A (en) 1996-09-19 1998-04-10 Bunshi Bio Photonics Kenkyusho:Kk Microscope apparatus
US6175107B1 (en) * 1998-05-27 2001-01-16 Owens-Brockway Glass Container Inc. Inspection of containers employing a single area array sensor and alternately strobed light sources
US6255642B1 (en) * 1999-06-23 2001-07-03 Massachusetts Institute Of Technology Standing wave total internal reflection imaging

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980831A (en) * 1996-06-17 1999-11-09 Braiman; Mark S. Support planar germanium waveguides for infrared evanescent-wave sensing
US6327238B1 (en) * 1997-08-29 2001-12-04 Matsushita Electric Industrial Co., Ltd. Optical disk device
US6144498A (en) * 1998-06-11 2000-11-07 Optical Coating Laboratory, Inc. Color separation prism assembly and method for making same

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9725764B2 (en) 1998-05-01 2017-08-08 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7645596B2 (en) 1998-05-01 2010-01-12 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US10214774B2 (en) 1998-05-01 2019-02-26 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US10208341B2 (en) 1998-05-01 2019-02-19 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US9957561B2 (en) 1998-05-01 2018-05-01 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US9096898B2 (en) 1998-05-01 2015-08-04 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US9212393B2 (en) 1998-05-01 2015-12-15 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US9458500B2 (en) 1998-05-01 2016-10-04 Life Technologies Corporation Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
US7897345B2 (en) 2003-11-12 2011-03-01 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US9657344B2 (en) 2003-11-12 2017-05-23 Fluidigm Corporation Short cycle methods for sequencing polynucleotides
US9012144B2 (en) 2003-11-12 2015-04-21 Fluidigm Corporation Short cycle methods for sequencing polynucleotides
US7981604B2 (en) 2004-02-19 2011-07-19 California Institute Of Technology Methods and kits for analyzing polynucleotide sequences
US9868978B2 (en) 2005-08-26 2018-01-16 Fluidigm Corporation Single molecule sequencing of captured nucleic acids
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids

Also Published As

Publication number Publication date
US20050057798A1 (en) 2005-03-17
US8139288B2 (en) 2012-03-20
GB2400518B (en) 2005-06-08
US7518764B2 (en) 2009-04-14
WO2003062897A1 (en) 2003-07-31
US20090237670A1 (en) 2009-09-24
GB0200938D0 (en) 2002-03-06
GB0416718D0 (en) 2004-09-01

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20230114