GB2394545B - Method of mass spectrometry - Google Patents

Method of mass spectrometry

Info

Publication number
GB2394545B
GB2394545B GB0321900A GB0321900A GB2394545B GB 2394545 B GB2394545 B GB 2394545B GB 0321900 A GB0321900 A GB 0321900A GB 0321900 A GB0321900 A GB 0321900A GB 2394545 B GB2394545 B GB 2394545B
Authority
GB
United Kingdom
Prior art keywords
mass spectrometry
spectrometry
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB0321900A
Other versions
GB0321900D0 (en
GB2394545A (en
Inventor
Scott Geromanos
Ashok Dongre
Gregory Opiteck
Jeffrey Silva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority claimed from GB0228653A external-priority patent/GB2385918B/en
Publication of GB0321900D0 publication Critical patent/GB0321900D0/en
Publication of GB2394545A publication Critical patent/GB2394545A/en
Application granted granted Critical
Publication of GB2394545B publication Critical patent/GB2394545B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB0321900A 2001-12-08 2002-12-09 Method of mass spectrometry Expired - Lifetime GB2394545B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34046001P 2001-12-08 2001-12-08
US36484702P 2002-03-14 2002-03-14
GB0228653A GB2385918B (en) 2001-12-08 2002-12-09 Method of mass spectrometry

Publications (3)

Publication Number Publication Date
GB0321900D0 GB0321900D0 (en) 2003-10-22
GB2394545A GB2394545A (en) 2004-04-28
GB2394545B true GB2394545B (en) 2005-03-16

Family

ID=32045681

Family Applications (3)

Application Number Title Priority Date Filing Date
GB0330041A Expired - Lifetime GB2396914B (en) 2001-12-08 2002-12-09 Method of mass spectrometry
GB0321900A Expired - Lifetime GB2394545B (en) 2001-12-08 2002-12-09 Method of mass spectrometry
GB0321898A Expired - Lifetime GB2395271B (en) 2001-12-08 2002-12-09 Method of mass spectrometry

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0330041A Expired - Lifetime GB2396914B (en) 2001-12-08 2002-12-09 Method of mass spectrometry

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0321898A Expired - Lifetime GB2395271B (en) 2001-12-08 2002-12-09 Method of mass spectrometry

Country Status (1)

Country Link
GB (3) GB2396914B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8704164B2 (en) 2002-07-24 2014-04-22 Micromass Uk Limited Mass analysis using alternating fragmentation modes

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
GB2413695B (en) * 2004-04-30 2009-01-21 Micromass Ltd Mass spectrometer
GB0409676D0 (en) 2004-04-30 2004-06-02 Micromass Ltd Mass spectrometer
GB0415046D0 (en) 2004-07-05 2004-08-04 Micromass Ltd Mass spectrometer
WO2006133109A1 (en) * 2005-06-03 2006-12-14 Waters Investments Limited Methods and apparatus for fractionation-based chemical analyses
GB2432712B (en) 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
GB0609253D0 (en) 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735777A (en) * 1985-03-11 1988-04-05 Hitachi, Ltd. Instrument for parallel analysis of metabolites in human urine and expired air
WO2000003240A1 (en) * 1998-07-10 2000-01-20 Cetek Corporation Method to detect and analyze tight-binding ligands in complex biological samples
US6017693A (en) * 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
WO2000060361A2 (en) * 1999-04-02 2000-10-12 Sequenom, Inc. Automated analysers
WO2001057518A2 (en) * 2000-02-02 2001-08-09 Yol Bolsum Canada Inc. Method of non-targeted complex sample analysis
JP2001330599A (en) * 2000-05-24 2001-11-30 Shimazu S D Kk Metabolic error screening diagnostic device by gc/ms
WO2002052259A1 (en) * 2000-12-26 2002-07-04 The Institute For Systems Biology Rapid and quantitative proteome analysis and related methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030031350A1 (en) * 2001-03-09 2003-02-13 Pe Corporation (Ny) Methods for large scale protein matching
DE10158860B4 (en) * 2001-11-30 2007-04-05 Bruker Daltonik Gmbh Mass spectrometric protein mixture analysis

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735777A (en) * 1985-03-11 1988-04-05 Hitachi, Ltd. Instrument for parallel analysis of metabolites in human urine and expired air
US6017693A (en) * 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
WO2000003240A1 (en) * 1998-07-10 2000-01-20 Cetek Corporation Method to detect and analyze tight-binding ligands in complex biological samples
WO2000060361A2 (en) * 1999-04-02 2000-10-12 Sequenom, Inc. Automated analysers
WO2001057518A2 (en) * 2000-02-02 2001-08-09 Yol Bolsum Canada Inc. Method of non-targeted complex sample analysis
JP2001330599A (en) * 2000-05-24 2001-11-30 Shimazu S D Kk Metabolic error screening diagnostic device by gc/ms
WO2002052259A1 (en) * 2000-12-26 2002-07-04 The Institute For Systems Biology Rapid and quantitative proteome analysis and related methods

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Biochemistry 1999, Vol. 38, pages 1757 - 1763. *
Electrophoresis 1999, Vol. 20, pages 3535 - 3550. *
Electrophoresis 1999, Vol. 20, pages 3551 - 3567. *
J. Proteome Research 2002, Vol. 1, No. 2, pages 161 - 168. *
Trends in Biotechnology 1997, Vol. 15, No. 10, pages 418 - 424. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8704164B2 (en) 2002-07-24 2014-04-22 Micromass Uk Limited Mass analysis using alternating fragmentation modes
US8809768B2 (en) 2002-07-24 2014-08-19 Micromass Uk Limited Mass spectrometer with bypass of a fragmentation device
US9196466B2 (en) 2002-07-24 2015-11-24 Micromass Uk Limited Mass spectrometer with bypass of a fragmentation device
US9384951B2 (en) 2002-07-24 2016-07-05 Micromass Uk Limited Mass analysis using alternating fragmentation modes

Also Published As

Publication number Publication date
GB0321898D0 (en) 2003-10-22
GB0321900D0 (en) 2003-10-22
GB2396914A (en) 2004-07-07
GB2394545A (en) 2004-04-28
GB2395271B (en) 2005-03-16
GB0330041D0 (en) 2004-01-28
GB2395271A (en) 2004-05-19
GB2396914B (en) 2005-06-22

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20221208