GB2372171A - Confocal imaging apparatus for imaging an object situated within a turbid medium - Google Patents

Confocal imaging apparatus for imaging an object situated within a turbid medium Download PDF

Info

Publication number
GB2372171A
GB2372171A GB0209151A GB0209151A GB2372171A GB 2372171 A GB2372171 A GB 2372171A GB 0209151 A GB0209151 A GB 0209151A GB 0209151 A GB0209151 A GB 0209151A GB 2372171 A GB2372171 A GB 2372171A
Authority
GB
United Kingdom
Prior art keywords
imaging
turbid medium
focal plane
light
confocal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0209151A
Other versions
GB0209151D0 (en
GB2372171B (en
Inventor
Beric Jonathan Read
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B J R SYSTEMS Ltd
Original Assignee
B J R SYSTEMS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B J R SYSTEMS Ltd filed Critical B J R SYSTEMS Ltd
Publication of GB0209151D0 publication Critical patent/GB0209151D0/en
Publication of GB2372171A publication Critical patent/GB2372171A/en
Application granted granted Critical
Publication of GB2372171B publication Critical patent/GB2372171B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0068—Optical details of the image generation arrangements using polarisation
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0048—Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0056—Optical details of the image generation based on optical coherence, e.g. phase-contrast arrangements, interference arrangements

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Endoscopes (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

An imaging apparatus is described which is suitable for imaging scenes contained within a turbid medium using a confocal effect. More particularly, a scanning means (3) is arranged to collect light form within the turbid medium and direct it to an imaging means (4, 5, and 6). The imaging means contains an aperture (5) which acts to reject all light from within the turbid medium except that from a specific focal plane. The imaging means then directs the light from the focal plane onto an optical receptor (72) for formation of an image of the scene contained at the focal plane. The apparatus may use any radiation, and in particular, visible light, IR and microwave wavebands are envisaged.

Description

AUK Patent Application,g,GB.,2 372 171,,,A (43) Date of Printing by UK
Office 14.08.2002 (21) Application No 0209151.0 (51) INTCL7 G02B 21/00
(22) Date of Filing 14.09.2000 (52) UK CL (Edition T) (30) Priority Data H4F FJB F18K F18R F27P (31) 9922468 (32) 22.09.1999 (33) GB
(56) Documents Cited by ISA (86) International Application Data EP 0793222A EP 0782027 A PCT/GB2000/003542 En 14.09.2000 WO 1999/046623A US 5153428A US 5035476 A US 4893008 A
(87) International Publication Data US 4478482 A WO2001/022146 En 29.03. 2001 BRAKENHOFF G J ET AL:"NOVEL CONFOCAL _ IMAGING AND VISUALIZATION TECHNIQUES"
PROCEEDINGS OF THE ROYAL MICROSCOPICAL
(71) Applicant(s) SOCIETY CONFERENCEIMICRO90),LONDON,2-6 B J R Systems Limited JUNE 1990,pages 247-250 XP000390782 page (Incorporated in the United Kingdom) 248 paragraph refigure 1 34 Windmill Avenue, St Albans, Hertfordshire, AL4 9TF, United Kingdom (58) Field of Search by ISA
INT CL7 G02B
(72) Inventor(s) WPI Data,PAJ,EPO-lnternal INSPEC Beric Jonathan Read (74) Agent and/or Address for Service A A Thornton & Co 235 High Holborn, LONDON, WC1V 7LE, United Kingdom (54) Abstract litie Confocal imaging apparatus for imaging an object situated within a turbid medium (57) An imaging apparatus is described which is suitable for imaging scenes contained within a turbid medium using a confocal effect. More particularly, a scanning means (3) is arranged to collect light form within the turbid medium and direct it to an imaging means (4, 5, and 67. The imaging means contains an aperture (5) which acts to reject all light from within the turbid medium except that from a specific focal plane. The imaging means then directs the light from the focal plane onto an optical receptor (72} for formation of an image of the scene contained at the focal plane. The apparatus may use any radiation, and in particular, visible light, IR and microwave wavebands are envisaged.
L 't6 ', i +
GB0209151A 1999-09-22 2000-09-14 Confocal imaging apparatus for imaging an object situated within a turbid medium Expired - Fee Related GB2372171B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922468.5A GB9922468D0 (en) 1999-09-22 1999-09-22 Confocal imaging apparatus for turbid viewing
PCT/GB2000/003542 WO2001022146A1 (en) 1999-09-22 2000-09-14 Confocal imaging apparatus for imaging an object situated within a turbid medium

Publications (3)

Publication Number Publication Date
GB0209151D0 GB0209151D0 (en) 2002-05-29
GB2372171A true GB2372171A (en) 2002-08-14
GB2372171B GB2372171B (en) 2004-07-28

Family

ID=10861421

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9922468.5A Ceased GB9922468D0 (en) 1999-09-22 1999-09-22 Confocal imaging apparatus for turbid viewing
GB0209151A Expired - Fee Related GB2372171B (en) 1999-09-22 2000-09-14 Confocal imaging apparatus for imaging an object situated within a turbid medium

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9922468.5A Ceased GB9922468D0 (en) 1999-09-22 1999-09-22 Confocal imaging apparatus for turbid viewing

Country Status (3)

Country Link
AU (1) AU7431800A (en)
GB (2) GB9922468D0 (en)
WO (1) WO2001022146A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2836727B1 (en) * 2002-03-04 2006-02-24 Vincent Lauer CONFOCAL OPTICAL SCANNING DEVICE
GB0706301D0 (en) 2007-03-30 2007-05-09 E2V Tech Uk Ltd Reflective means
DE102020210759A1 (en) 2020-08-25 2022-03-03 Robert Bosch Gesellschaft mit beschränkter Haftung Projector for illuminating a holographic projection surface for a vehicle, projection device for a vehicle and method for operating a projector

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4478482A (en) * 1981-05-11 1984-10-23 Koester Charles J Axial scanning optical system and method of examining an object plane
US4893008A (en) * 1987-06-09 1990-01-09 Olympus Optical Co., Ltd. Scanning optical microscope
US5035476A (en) * 1990-06-15 1991-07-30 Hamamatsu Photonics K.K. Confocal laser scanning transmission microscope
US5153428A (en) * 1990-06-15 1992-10-06 Hamamatsu Photonics K.K. Confocal laser scanning microscope having relay lens and a slit for removing stray light
EP0782027A2 (en) * 1988-07-13 1997-07-02 Optiscan Pty Ltd Scanning confocal microscope
EP0793222A2 (en) * 1996-02-28 1997-09-03 Hamamatsu Photonics K.K. Optical apparatus
WO1999046623A1 (en) * 1998-03-09 1999-09-16 Lucid, Inc. Imaging system using multi-mode laser illumination enhance image quality

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5467122A (en) * 1991-10-21 1995-11-14 Arete Associates Underwater imaging in real time, using substantially direct depth-to-display-height lidar streak mapping

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4478482A (en) * 1981-05-11 1984-10-23 Koester Charles J Axial scanning optical system and method of examining an object plane
US4893008A (en) * 1987-06-09 1990-01-09 Olympus Optical Co., Ltd. Scanning optical microscope
EP0782027A2 (en) * 1988-07-13 1997-07-02 Optiscan Pty Ltd Scanning confocal microscope
US5035476A (en) * 1990-06-15 1991-07-30 Hamamatsu Photonics K.K. Confocal laser scanning transmission microscope
US5153428A (en) * 1990-06-15 1992-10-06 Hamamatsu Photonics K.K. Confocal laser scanning microscope having relay lens and a slit for removing stray light
EP0793222A2 (en) * 1996-02-28 1997-09-03 Hamamatsu Photonics K.K. Optical apparatus
WO1999046623A1 (en) * 1998-03-09 1999-09-16 Lucid, Inc. Imaging system using multi-mode laser illumination enhance image quality

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRAKENHOFF G J ET AL:"NOVEL CONFOCAL IMAGING AND VISUALIZATION TECHNIQUES"PROCEEDINGS OF THE ROYAL MICROSCOPICAL SOCIETY CONFERENCE(MICRO90),LONDON,2-6 JUNE 1990,pages 247-250 XP000390782 page 248,paragraph 3;figure 1 *

Also Published As

Publication number Publication date
GB9922468D0 (en) 1999-11-24
GB0209151D0 (en) 2002-05-29
AU7431800A (en) 2001-04-24
WO2001022146A1 (en) 2001-03-29
GB2372171B (en) 2004-07-28

Similar Documents

Publication Publication Date Title
EP2267506A3 (en) Confocal microscopy with multi-spectral encoding
AU1885997A (en) Confocal microscope
CA2192986A1 (en) Autofocus system for scanning microscopy
JP2000517434A (en) Compact video microscope
EP1783528A3 (en) Fluorescence imaging system compatible with macro and micro scanning objectives
Michels Confocal laser scanning microscopy: using cuticular autofluorescence for high resolution morphological imaging in small crustaceans
EP0829707A3 (en) Compact fast imaging spectrometer
AU7389700A (en) Method and apparatus for reduction of trapezoidal distortion and improvement of image sharpness in an optical image capturing system
Carlsson et al. A confocal laser microscope scanner for digital recording of optical serial sections
Teubner et al. Optical Imaging and Photography: Introduction to Science and Technology of Optics, Sensors and Systems
EP0903930A3 (en) Image reading apparatus
GB2372171A (en) Confocal imaging apparatus for imaging an object situated within a turbid medium
Paddock et al. Rigidity of the nucleus during nuclear rotation in 3T3 cells
EP0777142A3 (en) Adapter for extracting a portion of an image from an optical system or device
Entwistle A comparison between the use of a high‐resolution CCD camera and 35 mm film for obtaining coloured micrographs
CA2466788A1 (en) Optical apparatus
Constantinou et al. A high-resolution MACROscope with differential phase contrast, transmitted light, confocal fluorescence, and hyperspectral capabilities for large-area tissue imaging
TWI714378B (en) A large-angle optical raster scanning system for high speed deep tissue imaging
JP2018169483A (en) Objective optical system for microscope and microscope using the same
Benedetti et al. Achieving confocal‐point performance in confocal‐line microscopy
US6545789B1 (en) Device to improve Z-axis resolution in confocal microscopy
Nase et al. A multiphoton laser scanning microscope setup for transcranial in vivo brain imaging on mice
Akioka Hα solar telescope at Hiraiso and its initial observations
Van der Oord et al. High‐resolution confocal microscopy using synchrotron radiation
Oates et al. Reading invisible ink: digital imaging of P. Duk. Inv. 716

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20170914