GB2369828B - Nuclear transfer with selected donor cells - Google Patents

Nuclear transfer with selected donor cells

Info

Publication number
GB2369828B
GB2369828B GB0205915A GB0205915A GB2369828B GB 2369828 B GB2369828 B GB 2369828B GB 0205915 A GB0205915 A GB 0205915A GB 0205915 A GB0205915 A GB 0205915A GB 2369828 B GB2369828 B GB 2369828B
Authority
GB
United Kingdom
Prior art keywords
donor cells
nuclear transfer
selected donor
nuclear
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0205915A
Other languages
English (en)
Other versions
GB0205915D0 (en
GB2369828A (en
Inventor
David Wells
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGRES Ltd
AgResearch Ltd
Original Assignee
AGRES Ltd
AgResearch Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AGRES Ltd, AgResearch Ltd filed Critical AGRES Ltd
Publication of GB0205915D0 publication Critical patent/GB0205915D0/en
Publication of GB2369828A publication Critical patent/GB2369828A/en
Application granted granted Critical
Publication of GB2369828B publication Critical patent/GB2369828B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
GB0205915A 1999-09-14 2000-09-14 Nuclear transfer with selected donor cells Expired - Fee Related GB2369828B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ337792A NZ337792A (en) 1999-09-14 1999-09-14 Nuclear transfer and use in cloning
PCT/NZ2000/000179 WO2001019182A1 (fr) 1999-09-14 2000-09-14 Transfert nucleaire utilisant des cellules donneuses selectionnees

Publications (3)

Publication Number Publication Date
GB0205915D0 GB0205915D0 (en) 2002-04-24
GB2369828A GB2369828A (en) 2002-06-12
GB2369828B true GB2369828B (en) 2004-12-01

Family

ID=19927507

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0205915A Expired - Fee Related GB2369828B (en) 1999-09-14 2000-09-14 Nuclear transfer with selected donor cells

Country Status (8)

Country Link
JP (1) JP2004500038A (fr)
CN (1) CN1424870A (fr)
AR (1) AR032284A1 (fr)
AU (1) AU784371B2 (fr)
DE (1) DE10084987T1 (fr)
GB (1) GB2369828B (fr)
NZ (1) NZ337792A (fr)
WO (1) WO2001019182A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1248640T3 (da) 2000-01-20 2007-02-12 Diabcell Pty Ltd Xenotransplantation af svineöer og deres fremstilling
CA2509465A1 (fr) * 2002-12-10 2004-06-24 Gtc Biotherapeutics, Inc. Procede et systeme d'utilisation d'embryons de transfert nucleaire cellulaire de cellule somatique en tant que donneurs de cellules pour un transfert nucleaire supplementaire
JP2006081542A (ja) * 2004-08-18 2006-03-30 Institute Of Physical & Chemical Research クローン哺乳動物の作成方法
JP2010075099A (ja) * 2008-09-26 2010-04-08 Japan Science & Technology Agency 哺乳動物核移植胚のスクリーニング方法、非ヒト哺乳動物核移植胚、クローン非ヒト哺乳動物、及びスクリーニングキット
WO2016036754A1 (fr) * 2014-09-02 2016-03-10 The Regents Of The University Of California Procédés et compositions pour assurer la modification de l'adn cible arn dépendante
CN105483216B (zh) * 2015-11-30 2019-01-15 四川农业大学 一种家兔cetp基因检测肉质育种的方法
CN108624621B (zh) * 2018-01-17 2019-04-12 中国科学院上海生命科学研究院 非人灵长类的体细胞克隆动物的制备方法
MX2022011245A (es) 2020-03-11 2023-01-11 Bit Bio Ltd Método de generación de células hepáticas.
CN111793671A (zh) * 2020-07-22 2020-10-20 中国农业大学 一种优化的适用于绵羊染色体二元流式分选的染色体悬液制备方法
CN112715479A (zh) * 2021-01-06 2021-04-30 吉沙阿牛 一种山羊生态循环养殖方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046982A1 (fr) * 1998-03-16 1999-09-23 Relag Pty Ltd Transfert de noyau de cellules porcines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046982A1 (fr) * 1998-03-16 1999-09-23 Relag Pty Ltd Transfert de noyau de cellules porcines

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
Biol. Reprod., Vol.46, 1992, Collas, P. et al., "Influence of cell cycle stage of the donor...", pp.492-500. *
Biol. Reprod., Vol.49, 1993, Campbell, K. H. S. et al., "Nuclear-cytoplasmic interactions...", pp.933-942. *
Biol. Reprod., Vol.60, 1999, Boquest, A. C. et al., "Flow cytometric cell cycle analysis...", pp.1013-1019. *
Mol. Reprod. Dev., Vol.39, 1994, Otaegui, P. J. et al., "Transfer of nuclei from 8-cell stage...", pp.147-152. *
Mol. Reprod. Dev., Vol.40, 1995, Pinto-Correia, C. et al., "Factors involved in nuclear reprogramming...", pp.292-304. *
P.N.A.S., Vol.96, 1999, Wakayama, T. et al., "Mice cloned from embryonic stem cells", pp.14984-14989. *
Science, Vol.280, 1998, Cibelli, J. B. et al., "Cloned transgenic calves...", pp.1256-1258. *

Also Published As

Publication number Publication date
AU7462400A (en) 2001-04-17
CN1424870A (zh) 2003-06-18
GB0205915D0 (en) 2002-04-24
DE10084987T1 (de) 2003-04-17
JP2004500038A (ja) 2004-01-08
AU784371B2 (en) 2006-03-23
AR032284A1 (es) 2003-11-05
NZ337792A (en) 2002-03-28
WO2001019182A1 (fr) 2001-03-22
GB2369828A (en) 2002-06-12

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20070914