GB2368846A - A lung cancer associated retrovirus gene delivery vector and methods of use th ereof - Google Patents

A lung cancer associated retrovirus gene delivery vector and methods of use th ereof

Info

Publication number
GB2368846A
GB2368846A GB0203028A GB0203028A GB2368846A GB 2368846 A GB2368846 A GB 2368846A GB 0203028 A GB0203028 A GB 0203028A GB 0203028 A GB0203028 A GB 0203028A GB 2368846 A GB2368846 A GB 2368846A
Authority
GB
United Kingdom
Prior art keywords
methods
ereof
lung cancer
gene delivery
cancer associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0203028A
Other versions
GB0203028D0 (en
GB2368846B (en
Inventor
Hung Y Fan
Massimo Palmarini
James M Sharp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of GB0203028D0 publication Critical patent/GB0203028D0/en
Publication of GB2368846A publication Critical patent/GB2368846A/en
Application granted granted Critical
Publication of GB2368846B publication Critical patent/GB2368846B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/12011—Betaretrovirus, e.g. mouse mammary tumour virus
    • C12N2740/12021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/12011—Betaretrovirus, e.g. mouse mammary tumour virus
    • C12N2740/12041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/12043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A viral genomic sequence of Jaagsiekte sheep retrovirus (JSRV) is provided and characterized herein. Also provided are methods of using the JSRV in gene therapy and in the treatment and diagnosis of JSRV related disorders.
GB0203028A 1999-07-08 2000-07-08 Isolated Jaagsiekte retroviruses (JSRV), gene delivery vectors, and methods of use Expired - Fee Related GB2368846B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14286899P 1999-07-08 1999-07-08
PCT/US2000/018856 WO2001004266A1 (en) 1999-07-08 2000-07-08 A lung cancer associated retrovirus, gene delivery vector and methods of use thereof

Publications (3)

Publication Number Publication Date
GB0203028D0 GB0203028D0 (en) 2002-03-27
GB2368846A true GB2368846A (en) 2002-05-15
GB2368846B GB2368846B (en) 2004-08-25

Family

ID=22501614

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0203028A Expired - Fee Related GB2368846B (en) 1999-07-08 2000-07-08 Isolated Jaagsiekte retroviruses (JSRV), gene delivery vectors, and methods of use

Country Status (3)

Country Link
AU (1) AU6085500A (en)
GB (1) GB2368846B (en)
WO (1) WO2001004266A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2004104032A2 (en) 2003-05-14 2004-12-02 The University Of Iowa Research Foundation Methods and compositions related to high-titer pseudotyped retroviruses
EP2306823A4 (en) 2008-06-30 2012-09-26 Tocagen Inc Formulations of 5-fluorocytosine and uses thereof
ES2706899T3 (en) 2008-09-26 2019-04-01 Tocagen Inc Vectors of gene therapy and cytosine deaminase
US8829173B2 (en) 2008-09-26 2014-09-09 Tocagen Inc. Recombinant vectors
US9669049B2 (en) 2010-10-31 2017-06-06 Tocagen Inc. Compositions comprising gamma retrovirus vectors and methods of treating proliferative disorders
US11065311B2 (en) 2012-10-25 2021-07-20 Denovo Biopharma Llc Retroviral vector with mini-promoter cassette
US9642921B2 (en) 2012-12-20 2017-05-09 Tocagen Inc. Cancer combination therapy and recombinant vectors
ES2779149T3 (en) 2014-03-26 2020-08-13 Tocagen Inc Retroviral vector that has immunostimulatory activity
KR20180048743A (en) 2015-09-04 2018-05-10 토카겐 인크. 2A < / RTI > peptide.
CN115433719B (en) * 2022-10-10 2024-10-18 吉林大学 Sheep-derived immortalized cell line for preparing various viruses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849718A (en) * 1994-12-19 1998-12-15 Medical Research Council Targeting complexes and use thereof
US5858990A (en) * 1997-03-04 1999-01-12 St. Elizabeth's Medical Center Fas ligand compositions for treatment of proliferative disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676455A1 (en) * 1991-05-17 1992-11-20 Inst Nat Sante Rech Med Retrovirus JSRV - Nucleic acid and proteins characteristic of this retrovirus - their applications in diagnosis and therapy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849718A (en) * 1994-12-19 1998-12-15 Medical Research Council Targeting complexes and use thereof
US5858990A (en) * 1997-03-04 1999-01-12 St. Elizabeth's Medical Center Fas ligand compositions for treatment of proliferative disorders

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. CLIN. INVEST., 1990, 86, 1945-1953, TJ STANDIFORD ET AL *
J. VIR., 1991, 65, 5061-5067, DF YORK ET AL *
J. VIR., 1992, 66, 4930-4939, DF YORK ET AL *

Also Published As

Publication number Publication date
GB0203028D0 (en) 2002-03-27
GB2368846B (en) 2004-08-25
AU6085500A (en) 2001-01-30
WO2001004266A9 (en) 2002-09-12
WO2001004266A1 (en) 2001-01-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20100708